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Cytokine storm and severe hepatitis in pregnancy due to herpes simplex virus 2.
Mularoni, Alessandra; Cona, Andrea; Ribeiro Dias, Lùcia; Bulati, Matteo; Busà, Rosalia; Castelbuono, Salvatore; Lo Porto, Davide; Pietrosi, Giada; Liotta, Rosa; Conaldi, Pier Giulio; Grossi, Paolo Antonio; Luppi, Mario.
Infection ; 52(1): 259-263, 2024 Feb.
Article in English | MEDLINE | ID: mdl-37759073

ABSTRACT

CASE PRESENTATION: A pregnant woman developed hepatitis due to a herpes simplex virus 2 primary infection with a severe systemic inflammatory response. Treatment with acyclovir and human immunoglobulin was given and both mother and baby survived. PURPOSE: We provide the first description of the inflammatory response associated with herpetic hepatitis in pregnancy.


Subject(s)
Hepatitis A , Hepatitis , Herpes Simplex , Pregnancy Complications, Infectious , Pregnancy , Female , Humans , Herpesvirus 2, Human , Herpes Simplex/diagnosis , Herpes Simplex/drug therapy , Pregnancy Complications, Infectious/diagnosis , Pregnancy Complications, Infectious/drug therapy , Cytokine Release Syndrome/complications , Acyclovir/therapeutic use , Hepatitis/complications
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