Heavy rainfall triggers increased nocturnal flight in desert populations of the Pacific black duck (Anas superciliosa).

Understanding of avian nocturnal flight comes mainly from northern hemisphere species in seasonal temperate ecosystems where nocturnal flight is often precisely timed and entrained by annual photoperiod. Here we investigate patterns of nocturnal flight in waterbirds of Australian desert ecosystems that fly considerable distances to find temporary water bodies formed from rainfall which is highly unpredictable seasonally and spatially, and when there is sufficient water, they then breed. How they perform these feats of navigation and physiology remain poorly known. Using GPS tracking of 38 satellite tagged Pacific black ducks (Anas superciliosa) in two contrasting ecosystems, before and after heavy rainfall we revealed a key role for facultative nocturnal flight in the movement ecology of this species. After large rainfall events, birds rapidly increased nocturnal flight activity in the arid aseasonal ecosystem, but not in the mesic seasonal one. Nocturnal flights occurred throughout the night in both ecosystems. Long range flights (>50 km in 2 hours) occurred almost exclusively at night; at night the distance flown was higher than during the day, birds visited more locations, and the locations were more widely dispersed. Our work reveals that heavy rainfall triggers increased nocturnal flight activity in desert populations of waterbirds.

Extreme nomadism in desert waterbirds: flights of the banded stilt.

In contrast to well-studied Northern Hemisphere birds with spatially and temporally predictable seasonal migrations, waterbirds in desert biomes face major challenges in exploiting stochastic, rich, yet short-lived resource pulses in vast arid landscapes, leading to the evolution of nomadic behaviour. An extreme example is the banded stilt (Cladorhynchus leucocephalus), an opportunistic colonial breeder at remote inland salt lakes after infrequent rain events. Using satellite telemetry on 21 birds (tracked for a mean of 196.2 days), we reveal extensive, rapid and synchronized movement among individuals to and from salt lakes. Two birds left coastal refugia for the inland following rain, flying 1000-2000 km, while 12 others rapidly moved a mean of 684 km (range 357-1298 km) away from drying inland sites to the coast. Two individuals moved longitudinally across the continent, departing and arriving at the same points, yet travelling very different routes; one bird moving more than 2200 km in less than 2.5 days, the other more than 1500 km in 6 days. Our findings reveal movements nearly twice as long and rapid as recorded in other desert waterbirds. We reveal capability to rapidly detect and exploit ephemeral wetland resource pulses across the stochastic Australian desert.

Historia natural del carcinoma hepatocelular en una cohorte de pacientes de un hospital comarcal / No disponible

Introducción: el carcinoma hepatocelular (CHC) es una neoplasiacon una elevada incidencia y una alta mortalidad.Objetivo: nuestro objetivo es la descripción de la historia naturalde una cohorte de pacientes con CHC e identificar variablesasociadas a supervivencia.Material y métodos: estudio retrospectivo y descriptivo depacientes diagnosticados de CHC entre 1995-2002. Las variablescualitativas se expresaron mediante frecuencias y porcentajes y lascuantitativas con mediana y desviación típica. La supervivencia seestimó mediante el método de Kaplan Meyer y la prueba de LogRank.Resultados: se analizaron un total de 154 pacientes con CHC.La ratio hombre-mujer fue de 2,9/1. La edad media de 68 ± 9 años.El 82% de los pacientes fueron exitus en un tiempo medio de seguimientode 28 meses. La mediana de supervivencia fue de 21,5 meses(IC 95%: 16,98-26,04). Se realizó tratamiento con intención curativaen un 40,3% y el resto tratamiento paliativo. Las variablesasociadas a la supervivencia fueron: presencia o no de ascitis, el númerode lesiones en el momento del diagnóstico y si el tratamientorealizado fue con intención curativa o no. No hubieron diferenciasestadísticamente significativas respecto a: sexo, edad, etiología de lacirrosis y estadio de Child en el momento del diagnóstico.Conclusiones: los factores asociados a una menor supervivenciaen los pacientes con carcinoma hepatocelular fueron lapresencia de ascitis y el número de lesiones en el momento deldiagnóstico. La realización de tratamiento con intención curativase asocia a una mayor supervivencia

Background: hepatocellular carcinoma (HCC) is a cancerwith high incidence and mortality.Objective: our aim was to describe the natural history of a patientcohort with HCC, and to identify the factors associated withsurvival.Patients and methods: a retrospective and descriptive studyof patients diagnosed with HCC between 1995 and 2002. Qualitativevariables were expressed as frequencies and percentages.Quantitative variables were expressed as medians and standarddeviations. Survival was calculated using the Kaplan-Meier methodand log rank.Results: a total of 154 patients were analyzed. The men-towomenratio was 2.9/1. Mean age was 68 ± 9 years. 82% of patientsdied during a median follow-up of 28 months. Median survivalwas 21.5 months (95% CI: 16.98-26.04). Curativetreatment was done in 40.3% of diagnosed patients, and 59.7%of patients received palliative treatment. Factors associated withsurvival were: ascites, number of lesions at diagnosis, and curativetreatment. No statistical differences were found for the next factors:age, sex, etiology of cirrhosis, and Child-Pugh stage at diagnosis.Conclusions: factors associated with low survival in patientswith HCC were ascites and number of lesions. Curative treatmentis associated with a higher survival when compared to palliative treatment

[Natural history of hepatocellular carcinoma in a cohort of pacients from a county hospital]. / Historia natural del carcinoma hepatocelular en una cohorte de pacientes de un hospital comarcal.

BACKGROUND: hepatocellular carcinoma (HCC) is a cancer with high incidence and mortality. OBJECTIVE: our aim was to describe the natural history of a patient cohort with HCC, and to identify the factors associated with survival. PATIENTS AND METHODS: a retrospective and descriptive study of patients diagnosed with HCC between 1995 and 2002. Qualitative variables were expressed as frequencies and percentages. Quantitative variables were expressed as medians and standard deviations. Survival was calculated using the Kaplan-Meier method and log rank. RESULTS: a total of 154 patients were analyzed. The men-to-women ratio was 2.9/1. Mean age was 68 +/- 9 years. 82% of patients died during a median follow-up of 28 months. Median survival was 21.5 months (95% CI: 16.98-26.04). Curative treatment was done in 40.3% of diagnosed patients, and 59.7% of patients received palliative treatment. Factors associated with survival were: ascites, number of lesions at diagnosis, and curative treatment. No statistical differences were found for the next factors: age, sex, etiology of cirrhosis, and Child-Pugh stage at diagnosis. CONCLUSIONS: factors associated with low survival in patients with HCC were ascites and number of lesions. Curative treatment is associated with a higher survival when compared to palliative treatment.

Study of the evolution of masked bifascicular block.

Masked bifascicular block (MBB) (absent or minimal S in I and VL, high R in Vi and AQRS approximately -60 degrees) is a rare condition. We have found 16 such cases in the last 12 years, thirteen male and three female, mean age 70 +/- 9 years. The conventional electrocardiogram was tabulated and the clinical features and evolution of the patients were followed over 39.1 +/- 32 months. Ten patients required pacemakers, nine because of complete atrioventricular (AV) block or increase in the previous AV block. Seven patients died (follow-up 27.3 +/- 32 months), five from heart failure. This study shows: (1) MBB is a subgroup of patients with a high risk of advanced atrioventricular block; (2) a pacemaker implant does not significantly reduce the high mortality in this group because of the severity of the underlying disease; (3) these results should be evaluated in a larger series of patients in order to confirm our provisional results.

Electrocardiographic and vectorcardiographic study of interatrial conduction disturbances with left atrial retrograde activation.

From 81,000 ECGs we collected 83 cases that fulfilled the criteria of Interatrial Conduction Disturbances with Left Atrial Retrograde Activation (IACD-LARA) (P +/- in II, III and VF with P width greater than or equal to 120 msec.). We present the detailed study of 35 cases with surface ECG and VCG and 29 cases with orthogonal ECG leads. The results are then compared against two control groups: with cardiopathy (30 cases) and without cardiopathy (25 cases). The prevalence of IACD-LARA was nearly 1% globally, and 2% among patients with valvular heart disease. The diagnostic criteria for IACD-LARA are: 1) ECG: P +/- in II, III and VF with P greater than or equal to 120 msec. with open angle (usually greater than 90 degrees) between the first and the second part of the P.2) Orthogonal ECG: P +/- in Y lead with a negative mode greater than 40 msec. 3) VCG: More than 50 msec. above the X or Z axis, duration of the P loop greater than or equal to 110 msec., open angle between the two parts of the P loop in both frontal (131.3 degrees +/- 32.3) and right sagital planes (171.2 degrees +/- 15.1), and presence of notches and slurrings in the last part of the P loop.

Radiation protection of glycine and glycylglycine.

The protective action of a series of organic sulfur compounds and amino acids has been investigated by using glycine and glycylglycine as substrates. A linear relationship is shown to exist between the reciprocal of the G-m value for the substrate in the presence of the protecting agent, and the concentration of this protecting agent. The "protecting activity" of the agents, expressed as the ratio of the rate constants for the reaction of radicals with the protecting agent and the substrate, is determined.