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1.
World Allergy Organ J ; 11(1): 9, 2018.
Article in English | MEDLINE | ID: mdl-29796150

ABSTRACT

BACKGROUND: Atopic disorders are a global concern. Studies in migrant populations can illuminate the interplay of genetic and environmental factors. Exposures related to bad housing (indoor dampness, mould growth, crowding etc.) are likely to play a role in how socioeconomic inequalities can turn into health disparities for disadvantaged populations. The sizable immigrant population living in very poor-quality housing in Malmö, Sweden, became the focus of a cross-sectional study. OBJECTIVE: To describe atopic disorders and sensitizations in a population living in substandard housing in Malmö, Sweden, with an emphasis on their relation to harmful exposures from the built environment. METHODS: Families were recruited via identification of any children with symptomatic airway afflictions from health care records, and also asymptomatic children from school lists. Interviewer-led health questionnaire data and data from self-reports about living conditions were obtained together with data from home inspections carried out by health communicators. Families underwent skin prick tests (SPT) against common aeroallergens. RESULTS: As could be expected from background demographic information, it turned out that we effectively studied an immigrant population inhabiting very precarious housing outside the center of Malmö. A total of 359 children from 130 families (total 650 participants) were included. Overall the prevalence of potentially harmful environmental exposures was high (signs of moisture or mould in more than 50% of apartments, indoor smoking in 37% of households). Atopic disorders were common among both adults and children. SPTs showed a spectrum of sensitizations consistent with unselected populations in Sweden. Paternal sensitization in the SPT was associated with higher risk of sensitization for offspring than maternal sensitization. Few statistically significant associations of atopic sensitization with studied environmental exposures were detected (for example objective signs of dampness /mould in bathrooms). There were marked discrepancies between asthma diagnoses obtained from the health records and parental reports of such diagnoses and treatment for their children. CONCLUSIONS: The atopic burden in this selected immigrant population was high, and results point to unmet medical needs. Health care systems caring for such populations need to be aware of their specific health needs; comprehensive asthma and allergy care should include consideration of harmful environmental exposures, adhering to the precautionary principle.

2.
Dtsch Med Wochenschr ; 134(38): 1869-71, 2009 Sep.
Article in German | MEDLINE | ID: mdl-19746328

ABSTRACT

HISTORY AND CLINICAL FINDINGS: A 69-year-old man was admitted with cough, fever and dyspnea. For years, an adrenal insufficiency has been substituted with low-dose hydrocortisone. The hypotensive and tachycardic patient exhibited remarkable stony hard ears. INVESTIGATIONS: Elevated inflammatory markers and the clinical picture point to a pulmonary focus of infection. Radiographs of the ears show trabecular structures as a sign of true ossification. DIAGNOSIS, TREATMENT AND COURSE: Addisonian crisis due to pulmonary infection was treated successfully with steroids, antibiotics and intravenous fluids. The auricular ossification was interpreted as a secondary phenomenon of undersubstituted adrenal insufficiency. CONCLUSION: Adrenal insufficiency should be considered when auricular ossification is encountered. The pathogenesis of this phenomenon is complex and not well understood.


Subject(s)
Addison Disease/complications , Anti-Inflammatory Agents/administration & dosage , Calcinosis/etiology , Ear Diseases/etiology , Hydrocortisone/administration & dosage , Ossification, Heterotopic/etiology , Addison Disease/drug therapy , Aged , Anti-Inflammatory Agents/adverse effects , Calcinosis/diagnosis , Cartilage/diagnostic imaging , Cartilage/pathology , Ear Diseases/diagnosis , Humans , Hydrocortisone/adverse effects , Legionnaires' Disease/complications , Legionnaires' Disease/diagnosis , Male , Ossification, Heterotopic/diagnosis , Radiography
3.
Gen Hosp Psychiatry ; 30(4): 360-6, 2008.
Article in English | MEDLINE | ID: mdl-18585541

ABSTRACT

BACKGROUND: Psychiatric emergency situations (PES) are of high importance to the German prehospital physician-based emergency medical system. So far, however, no prospective studies regarding the incidence of PES have been performed, neither have effects of training programs on diagnostic and therapeutic accuracy been studied. METHOD: The protocols of two emergency medical services (EMS) were collected and analyzed prospectively. Emergency physicians (EPs) in Kaiserslautern (KL) attended a standardized educational program and underwent daily supervision. EPs in Homburg (HOM) had not been informed about the study. In KL, sociodemographic variables were collected. An investigator who was not involved in the individual EMS mission assessed the correct classification of PES. RESULTS: Among all calls for an EP, 11.8% were classified as PES. There was no difference between the two centers. Correct classification of PES in KL was significantly higher than that in HOM (94.3% vs. 80.6%). Documentation of suicidal behavior was deficient in both centers. EPs in KL gave verbal crisis intervention significantly more often, administered less medication overall, and dispensed more specific drugs in psychotic disorders and significantly less drugs in substance abuse disorders. Patients were more often treated at the scene and were less often transported to a hospital. Some sociodemographic variables were associated with psychiatric morbidity of treatment. CONCLUSION: Accounting for 12% of all missions, psychiatric emergencies are a frequent reason for calls for EPs, equaling trauma-related and neurological emergencies. The most frequent reasons for calls were alcohol intoxication, states of agitation and suicidal behavior. The diagnostic and therapeutic accuracy of EPs may be improved with a concise standardized teaching program.


Subject(s)
Emergency Medicine/education , Emergency Service, Hospital/statistics & numerical data , Emergency Services, Psychiatric/statistics & numerical data , Mental Disorders/diagnosis , Mental Disorders/epidemiology , Physicians/statistics & numerical data , Urban Population/statistics & numerical data , Adult , Alcoholic Intoxication/diagnosis , Alcoholic Intoxication/epidemiology , Alcoholic Intoxication/therapy , Documentation/methods , Drug Utilization , Emergency Medicine/methods , Employment/statistics & numerical data , Female , Germany/epidemiology , Humans , Male , Marital Status/statistics & numerical data , Mental Disorders/drug therapy , Prospective Studies , Psychomotor Agitation/diagnosis , Psychomotor Agitation/epidemiology , Psychomotor Agitation/therapy , Suicide/psychology , Suicide/statistics & numerical data , Suicide, Attempted/classification , Suicide, Attempted/psychology , Suicide, Attempted/statistics & numerical data
4.
Psychosomatics ; 47(3): 223-30, 2006.
Article in English | MEDLINE | ID: mdl-16684939

ABSTRACT

The purpose of the study was to investigate the prevalence of posttraumatic stress disorder (PTSD) after prolonged intensive care unit (ICU) treatment and to study the differences between trauma patients and patients who were admitted with other diagnoses. Survivors of surgical intensive care of at least 30 days' duration underwent follow-up examination at about 35 months after discharge from the ICU. Thirty-seven patients were investigated. Seven patients met full DSM-IV criteria for diagnosis of PTSD. All of them had sustained severe multiple injuries. Patients with trauma were at significantly higher risk for developing PTSD than were non-trauma patients. After prolonged ICU treatment, PTSD seems more likely to occur when the reason for admission to the ICU was severe physical injury. The prevalence of PTSD does not seem to be related to injury severity or duration of ICU treatment.


Subject(s)
Critical Care/psychology , Interview, Psychological , Length of Stay , Multiple Trauma/psychology , Referral and Consultation , Stress Disorders, Post-Traumatic/psychology , Adult , Comorbidity , Female , Follow-Up Studies , Hospital Mortality , Humans , Male , Mental Disorders/diagnosis , Mental Disorders/psychology , Middle Aged , Multiple Trauma/mortality , Multiple Trauma/surgery , Personality Assessment , Psychopathology , Risk Factors , Stress Disorders, Post-Traumatic/diagnosis
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