ABSTRACT
BACKGROUND: Most surgeons calibrate the sleeve with 32-French (Fr) to 40-Fr bougies hypothesizing that smaller bougies are associated with greater weight loss and long-term lower weight regain. The purpose of this study was to assess the weight loss results and resolution of comorbidities 5 years after laparoscopic sleeve gastrectomy (LSG). METHODS: A prospective study of all the morbidly obese patients undergoing laparoscopic sleeve gastrectomy calibrated with a 50-Fr bougie between October 2007 and February 2010 was performed. Excess weight loss (EWL) and remission of comorbidities were investigated at 1, 2, and 5 years after surgery. RESULTS: Fifty patients were included for the analysis. One year after surgery, mean excess weight loss (EWL) of 81.8 % was achieved, type 2 diabetes mellitus (T2DM) resolution rate was 76.9 %, hypertension resolution was observed in 73.3 %, sleep apnea hypopnea syndrome (SAHS) resolution in 100 % hypertriglyceridemia was normalized in all the cases, and hypercholesterolemia in 21.4 %. Two years after surgery, mean EWL was 84.4 % and comorbidity resolution rate similar to that obtained after the first postoperative year. Five years after surgery, mean EWL was 78.7 %, T2DM resolution 69.2 %, hypertension 66.7 %, SAHS 100 %, hypertriglyceridemia 100 %, and hypercholesterolemia 14.3 %. CONCLUSIONS: LSG calibrated with a 50-Fr bougie obtained excellent results in weight loss and resolution comorbidities and their maintenance in the long-term follow-up in our series. In our opinion, the results depend more on a preoperative correct selection of candidates and a close postoperative follow-up, rather than using a narrow calibration bougie.
Subject(s)
Gastrectomy/methods , Laparoscopy/methods , Obesity, Morbid/surgery , Adult , Aged , Calibration , Comorbidity , Diabetes Mellitus, Type 2/etiology , Diabetes Mellitus, Type 2/surgery , Female , Follow-Up Studies , Gastrectomy/instrumentation , Humans , Hypertension/etiology , Hypertension/surgery , Hypertriglyceridemia/etiology , Hypertriglyceridemia/surgery , Male , Middle Aged , Obesity, Morbid/complications , Prospective Studies , Remission Induction , Treatment Outcome , Weight LossABSTRACT
Presentamos el caso de una paciente de 74 años con antecedentes de síndrome depresivo que ingresa en el servicio de psiquiatría por un cuadro maníaco en principio relacionado con un hipotiroidismo severo al dejar de tomar levotiroxina. Unos meses después la paciente ingresó en el servicio de medicina interna por disnea, artritis, úlceras bucales así como hipocomplementemia y elevación de ANA. Revisando la historia clínica de la paciente observamos que antes del brote maníaco la paciente tenía datos clínicos que indicaban actividad lúpica. Es importante identificar los síntomas neuropsiquiátricos en una paciente con lupus, ya que pueden ser la manifestación de inicio de la enfermedad en contraposición a un trastorno afectivo primario. Existen muy pocos casos descritos de psicosis secundaria a un hipotiroidismo aunque la relación entre los trastornos tiroideos y el lupus eritematoso sistémico no es tan rara (AU)
We present a case of a 74 year-old woman with a history of depression who was admitted to the psychiatric department due to having a maniacal clinical picture associated with a severe hypothyroidism on stopping taking levothyroxine. A few months later the patient was admitted to the internal medicine department because of dyspnea, arthritis, mouth ulcers and a low complement and increased ANA. Reviewing the history of the patient before the outbreak we observed that the patient had a clinical history showing lupus activity. It is important to identify neuropsychiatric symptoms in a patient with lupus, as they could be the initial onset of the illness as opposed to a primary affective disorder. There are very few cases of psychosis secondary to hypothyroidism, although the relationship between thyroid disorders and systemic lupus erythematosus is not so rare (AU)
