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1.
IEEE Trans Inf Technol Biomed ; 5(3): 248-52, 2001 Sep.
Article in English | MEDLINE | ID: mdl-11550847

ABSTRACT

Transducers represent a key component of medical instrumentation systems. In this paper, sensors that perform the task of measuring the physical quantity of acceleration are discussed. These sensors are of special significance since, by integrating their output signal, accelerometers can additionally provide a measure of velocity and position. Applications for such measurements and, thus, of accelerometers, range from early diagnosis procedures for tremor-related diseases (e.g., Parkinson's) to monitoring daily patterns of patient activity using telemetry systems. The system-level requirements in such applications are considered and two novel neural-network transducer designs developed by the authors are presented, which aim to satisfy such requirements. Both designs are based on a micromachined sensing element with capacitive signal pickoff. The first is an open-loop design utilizing a direct-inverse-control strategy, while the second is a closed-loop design, where electrostatic actuation is used as a form of feedback. Both transducers are nonlinearly compensated, capable of self-test, and provide digital outputs.


Subject(s)
Acceleration , Neural Networks, Computer , Telemedicine , Equipment Design , Humans , Telemetry , Transducers
2.
Proc Inst Mech Eng H ; 212(5): 373-81, 1998.
Article in English | MEDLINE | ID: mdl-9803156

ABSTRACT

This paper is intended as an overview of the research carried out at Coventry University in the design of a portable artificial kidney system. It was seen that the key to the problem was the reduction in dialysate volume, and so it was decided to develop a prototype that would utilize the regeneration and recirculation of a small volume of dialysate. A prototype system has been produced and used to simulate a dialysis session. Activated carbon was used as a sorbent for the regeneration of the dialysate, circulating in a closed loop. For the purpose of this work, the adsorption of urea was investigated as this is, volumetrically, the major solute to be removed. Peltier effect cooling was used to vary the dialysate temperature down to 2 degrees C, as activated carbon will adsorb greater amounts of urea at lower temperatures. A series of tests was then carried out to investigate the effect of dialysate temperature, flowrate and volume on the amount of urea that could be dialysed. From the experimental results, a model of the system was derived, which made it possible to determine the implications of different operating conditions on the overall mass and size of a portable dialysis system. The output of this model was then used to establish a design specification and produce an optimum design solution for the system.


Subject(s)
Charcoal/therapeutic use , Dialysis Solutions/therapeutic use , Kidneys, Artificial/standards , Adsorption , Algorithms , Decision Trees , Equipment Design , Evaluation Studies as Topic , Humans , Temperature , Time Factors , Urea/pharmacokinetics
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