1.
Proc Soc Exp Biol Med
; 150(3): 681-5, 1975 Dec.
Article
in English
| MEDLINE
| ID: mdl-174141
ABSTRACT
An interaction between sarcoma-180/TG cells and vesicular stomatitis virus in adult mice resulted in the rapid onset of extensive mortality. This interaction, termed lethal synergy, occurred only at early stages of ascites induction in animals with no prior virus contact. A significant sparing effect conferred by the serotonin antagonist dibenamine was reversed by the administration of serotonin. The cause of death was not determined, but a mechanism involving hypersensitivity is indicated.
Subject(s)
Sarcoma 180/mortality , Vesicular stomatitis Indiana virus/growth & development , Animals , Dibenzylchlorethamine/pharmacology , Female , Hypersensitivity , Mice , Neoplasm Transplantation , Sarcoma 180/immunology , Serotonin/pharmacology , Serotonin Antagonists , Vesicular stomatitis Indiana virus/immunology
2.
Antimicrob Agents Chemother
; 6(4): 524-5, 1974 Oct.
Article
in English
| MEDLINE
| ID: mdl-4157357
ABSTRACT
Extracts from two species of marine red algae, Cryptosyphonia woodii and Farlowia mollis, specifically inhibited herpes simplex virus replication in vitro.