ABSTRACT
BACKGROUND: Femoral head osteonecrosis (FHON) is a well-recognised complication in patients with human immunodeficiency virus (HIV) infection. Total hip arthroplasty (THA) is a reliable solution to FHON and has provided functional improvement and pain relief in these patients. Higher complication rates, in particular infections, have been reported in the series of THAs done in the HIV-positive patients. The purpose of this study was to evaluate the complication rate of THA for FHON in HIV-positive patients managed with the highly active antiretroviral therapy (HAART) protocols. METHODS: A retrospective review was performed of HIV-positive patients with FHON who underwent THAs over a 10-year period at a single institution. RESULTS: A total of 56 THAs (44 patients) met the inclusion criteria. The mean age at the time of THAs was 47 (range 34-60) years. Of the 44 patients, 39 (88.6%) were males. The mean follow-up was 6.6 (range 2.0-11.3) years. The overall complication rate was 12.5%, with 2 (3.6%) cases of deep periprosthetic infections. CONCLUSIONS: HIV-positive patients with FHON undergoing THAs do have a considerable complication rate (12.5%). The deep periprosthetic infection rate (3.6%) in these patients, however, has decreased with contemporary disease modification protocols.
Subject(s)
Arthroplasty, Replacement, Hip , Femur Head Necrosis , HIV Infections , Hip Prosthesis , Osteonecrosis , Male , Humans , Adult , Middle Aged , Female , Arthroplasty, Replacement, Hip/adverse effects , Arthroplasty, Replacement, Hip/methods , Femur Head/surgery , Prosthesis Failure , Osteonecrosis/surgery , HIV Infections/complications , HIV Infections/surgery , Retrospective Studies , HIV , Treatment Outcome , Femur Head Necrosis/etiology , Femur Head Necrosis/surgery , Hip Prosthesis/adverse effectsABSTRACT
OBJECTIVES: Inferior total knee arthroplasty (TKA) outcomes are reported in minority populations. Standardized TKA pathways improve outcomes but have not been studied extensively in minority populations. This study evaluated the impact of TKA pathway standardization at an urban teaching hospital that predominantly treats minority patients. STUDY DESIGN: Retrospective cohort study. METHODS: This study compared primary TKA outcomes before and after implementation of a standardized multidisciplinary pathway that emphasized preoperative education and discharge planning, preemptive multimodal pain control, and early rehabilitation. Patients were grouped as "nonpathway" (n = 144) or "pathway" (n = 182) based on whether they underwent TKA before or after pathway implementation. Outcomes included length of stay (LOS), patient-controlled analgesia (PCA) use, blood transfusion, postoperative hemoglobin, complications, and discharge disposition. Analysis involved negative binomial and multiple logistic regression models, t tests, and Fisher's exact tests. RESULTS: Mean (SD) age was 61.6 (8.7) years, and 36.5% were men. Ethnicity of the patients included Hispanic (44.5%), African American (27.9%), Asian (14.1%), and White (12.9%). Pathway and nonpathway patients were similar demographically and racially. Pathway patients had shorter LOS (P = .04), less PCA use (P < .001), more frequent discharge home (P = .03), fewer transfusions (P = .002), and higher postoperative hemoglobin (P < .001). Overall incidence of complications was similar (P = .61). Nonpathway patients developed more cardiopulmonary complications (P = .02), whereas pathway patients had more wound dehiscence (P = .01). CONCLUSIONS: Compared with nonpathway patients, standardized TKA pathway patients had shorter LOS, decreased PCA use, increased discharge to home, fewer blood transfusions, and higher postoperative hemoglobin, with no difference in total incidence of complication.
