1.
Clin Ter
; 133(5): 289-97, 1990 Jun 15.
Article
in Italian
| MEDLINE
| ID: mdl-2143712
ABSTRACT
In a 12-months double-blind study 42 obese patients (5 males, 37 females) were treated either with d-fenfluramine (30 mg daily) or with placebo plus low-calorie diet (1500-1200 kcal daily). Evaluation of treatment efficacy was based on evolution of the initial cohort, weight loss, number of subjects completing treatment, tolerability and events leading to dropout. Patients receiving d-fenfluramine had statistically significant greater weight loss than the placebo group; 30 mg daily proved to be an effective and well tolerated dose of d-fenfluramine with the best long-term activity/acceptability ratio.
Subject(s)
Obesity/drug therapy , Adult , Double-Blind Method , Female , Fenfluramine/administration & dosage , Fenfluramine/therapeutic use , Humans , Male , Obesity/diet therapy , Placebos , Randomized Controlled Trials as Topic
2.
Nuovi Ann Ig Microbiol
; 32(1-2): 73-81, 1981.
Article
in Italian
| MEDLINE
| ID: mdl-7343906