ABSTRACT
It was discovered that patients suffering from essential hypertension (EH) of the hypokinetic circulatory type (the cardiac index less than 2.7 1/min/m2) manifest an elevated level of energy metabolism which is mediated by the increased arteriovenous difference according to oxygen, accompanied by an increase in oxygen utilization ratio. In patients, the total peripheral resistance was higher as compared to that in normal subjects (P less than 0.01). In patients with EH of the hyperkinetic circulatory type (the cardiac index over 3.4 1/min/m2), there was a considerable increment of the outward work of the heart left ventricle, reduction in the arteriovenous difference according to oxygen, and diminution of the oxygen utilization ratio as compared with normal subjects. At the same time the energy metabolism and total peripheral vascular resistance did not differ from those in the control group (P greater than 0.05).
Subject(s)
Blood Circulation , Hypertension/physiopathology , Oxygen Consumption , Adult , Cardiac Output , Female , Humans , Male , Middle Aged , Vascular ResistanceSubject(s)
Myocarditis/diagnosis , Neurocirculatory Asthenia/diagnosis , Adolescent , Adult , Diagnosis, Differential , Exercise Test , Female , Humans , Male , Plethysmography, ImpedanceSubject(s)
Carbon Dioxide/physiology , Coronary Disease/rehabilitation , Hemodynamics , Oxygen/physiology , Adult , Carbon Dioxide/therapeutic use , Coronary Disease/physiopathology , Humans , Middle Aged , Myocardial Infarction/physiopathology , Myocardial Infarction/rehabilitation , Oxygen/therapeutic use , Respiratory Therapy/methodsABSTRACT
Of the 210 patients who underwent direct coronary surgery for stable and unstable angina pectoris and acute myocardial ischemia, 187 were followed up after the operation for 11 months on the average. Operative mortality was 11%. Among the 187 patients, 46.5% were completely relieved of angina, 36.4% showed moderate improvement, and 16.9% had no improvement in their condition. Patients with prior myocardial infarction had a substantially diminished success rate for relief of angina. Postoperative angiography in 125 patients demonstrated high correlation between clinical response and graft patency. It is concluded that direct coronary surgery provides partial or complete relief of angina pectoris in 82.9% of patients, and this response to operative treatment may be directly related to the success of the surgery ensuring patency of the graft, evidence of which is demonstrated by angiography.
