Subject(s)
Disease Outbreaks/statistics & numerical data , Measles Vaccine/therapeutic use , Measles/epidemiology , Measles/prevention & control , Population Surveillance , Risk Assessment/methods , Vaccination/statistics & numerical data , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Humans , Incidence , Infant , Infant, Newborn , Male , Middle Aged , Republic of Belarus/epidemiology , Risk FactorsABSTRACT
Resistance of hospital Staphylococci to beta-lactam antibiotics was studied. The strains were isolated in two obstetric hospitals during an outbreak of purulent inflammatory infections in them. A modification of the "clover leaf" procedure providing elucidation of the resistance mechanism was used in the study. Development of the resistance to the beta-lactam antibiotics was shown to be mainly due the activity of beta-lactamases which makes it possible to discuss their role in the mechanism of resistance development.
Subject(s)
Anti-Bacterial Agents/pharmacology , Cross Infection/microbiology , Staphylococcus aureus/drug effects , Drug Resistance, Microbial/physiology , Humans , Microbial Sensitivity Tests , Staphylococcus aureus/isolation & purification , beta-LactamsABSTRACT
Sensitivity of 267 strains of pathogenic staphylococci isolated in 1974 was studied with respect to some antibiotics and nitrofuran derivatives by the method of serial dilutions on solid media. Sensitivity to penicillin, oxacillin, olemorphocycline, ristomycin and nitrofuran derivatives (furagin and salafur) was observed in 30.7 +/- 2.8, 61.8 +/-3, 29.2 +/-2.8 and 98.9 +/- 0.8 per cent of the cultures respectively.