ABSTRACT
Besides the lungs, the liver is the second most common site of hematogenous metastases from carcinomata of the breast. Hepar lobatum carcinomatosum is the rarest form of metastatic liver disease. Reported in this article is a case of a 59-year-old woman with invasive duct carcinoma of the breast with metastasis to the axillar lymph nodes and liver, treated with ablatio mammae and combination of chemotherapy. The etiology of hepar lobatum is caused by multiple pathogenetic factors. Tumor-related multifocal obstruction of portal and hepatic venous vessels and effects of chemotherapy are discussed.
Subject(s)
Antineoplastic Combined Chemotherapy Protocols/adverse effects , Breast Neoplasms/pathology , Carcinoma, Ductal, Breast/pathology , Chemical and Drug Induced Liver Injury , Liver Neoplasms/secondary , Female , Humans , Liver Neoplasms/complications , Liver Neoplasms/drug therapy , Middle Aged , Tomography, X-Ray ComputedABSTRACT
From the viewpoint of a ward hospital the possibilities of the diagnostics of a thrombosis of the deep leg vein and/or the pelvic vein are discussed. The most important and at the same time most practicable method is the phlebography of the ascending leg vein. Indications, contraindications, technique and possible complications are mentioned. In most cases the fibrinolysis therapy is the therapy of choice. The results of the last years show that less the age, but more the location of the thrombus is decisive for a successful recanalisation.
