ABSTRACT
A pregnant woman with acute hepatitis B virus (HBV) infection had her second pregnancy terminated at 25 weeks' gestation because of fetal ascites and ventriculitis. Meconium peritonitis was also found at autopsy. No HBV DNA but cytomegalovirus (CMV) DNA was detected in the fetal liver and ascitic fluid. Recurrent maternal CMV infection was demonstrated by pre-existing CMV IgG antibodies, high IgG avidity and low IgM levels. After abortion, the patient developed chronic active hepatitis. Nevertheless, having become pregnant again with a new partner, she had an uneventful third pregnancy and gave birth to a healthy boy.
Subject(s)
Cytomegalovirus Infections/congenital , Fetal Diseases/virology , Hepatitis B/complications , Infectious Disease Transmission, Vertical , Pregnancy Complications, Infectious , Abnormalities, Multiple/diagnostic imaging , Abnormalities, Multiple/embryology , Abortion, Therapeutic , Acute Disease , Adult , Antibodies, Viral/blood , Ascites/diagnostic imaging , Ascites/embryology , Ascites/virology , Brain Diseases/diagnostic imaging , Brain Diseases/embryology , Cytomegalovirus/genetics , Cytomegalovirus/immunology , Cytomegalovirus/isolation & purification , Cytomegalovirus Infections/complications , Cytomegalovirus Infections/transmission , DNA, Viral/isolation & purification , Female , Fetal Diseases/diagnostic imaging , Fetal Diseases/embryology , Humans , Liver/virology , Pregnancy , Pregnancy Trimester, Second , Recurrence , Ultrasonography, PrenatalABSTRACT
OBJECTIVES: To evaluate the effect of age, years since menopause and body weight on bone mass density (BMD) in 283 patients. METHODS: Bone mass density was assessed by bone computerized mineralometry at two sites of the forearm. RESULTS: The mean distal BMD and ultra BMD in the postmenopausal group were negatively correlated with age (P < 0.001, r = -0.48 and P < 0.001, r = -0.50, respectively) and years since menopause (P < 0.001, r = -0.32 and P < 0.001, r = -0.33, respectively). When body-mass index was regressed against distal and ultra distal BMD, positive correlations were found (P = 0.008 and P = 0.007). CONCLUSIONS: From our data, forearm computerized mineralometry seems to be a reliable method for the evaluation of the effects of age and body-mass index on bone mass.
