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1.
Sci Rep ; 11(1): 22742, 2021 11 23.
Article in English | MEDLINE | ID: mdl-34815495

ABSTRACT

Management of diabetes-related foot ulceration (DFU) includes pressure offloading resulting in a period of reduced activity. The metabolic effects of this are unknown. This study aims to investigate changes in bone mineral density (BMD) and body composition 12 weeks after hospitalisation for DFU. A longitudinal, prospective, observational study of 22 people hospitalised for DFU was conducted. Total body, lumbar spine, hip and forearm BMD, and total lean and fat mass were measured by dual-energy X-ray absorptiometry (DXA) during and 12 weeks after hospitalisation for DFU. Significant losses in total hip BMD of the ipsilateral limb (- 1.7%, p < 0.001), total hip BMD of the contralateral limb (- 1.4%, p = 0.005), femoral neck BMD of the ipsilateral limb (- 2.8%, p < 0.001) and femoral neck BMD of the contralateral limb (- 2.2%, p = 0.008) were observed after 12 weeks. Lumbar spine and forearm BMD were unchanged. HbA1c improved from 75 mmol/mol (9.2%) to 64 mmol/mol (8.0%) (p = 0.002). No significant changes to lean and fat mass were demonstrated. Total hip and femoral neck BMD decreased bilaterally 12 weeks after hospitalisation for DFU. Future research is required to confirm the persistence and clinical implications of these losses.


Subject(s)
Bone Density , Diabetes Mellitus/physiopathology , Diabetic Foot/pathology , Femur Neck/pathology , Hospitalization/statistics & numerical data , Lumbar Vertebrae/pathology , Osteoporosis/pathology , Australia/epidemiology , Body Composition , Diabetic Foot/complications , Diabetic Foot/epidemiology , Female , Humans , Male , Middle Aged , Osteoporosis/etiology , Prospective Studies
2.
Intern Med J ; 51(7): 1146-1150, 2021 Jul.
Article in English | MEDLINE | ID: mdl-34278684

ABSTRACT

The use of telephone and/or video consultation in routine management of acute diabetes-related foot disease (DFD) before the coronavirus disease 2019 (COVID-19) pandemic at a tertiary hospital is unprecedented. In March 2020, the Diabetes Feet Australia (DFA) released a national guideline to inform DFD management during the COVID-19 pandemic. The present study aimed to describe the adherence to the DFA guideline of managing acute DFD using telephone and/or video consultation at a Western Australian tertiary hospital during this period. We found >80% adherence rate to the DFA guideline and the management of active DFD using telephone and/or video consultations was feasible and acceptable in carefully selected patients.


Subject(s)
COVID-19 , Diabetes Mellitus , Foot Diseases , Telemedicine , Australia/epidemiology , Humans , Outpatients , Pandemics , SARS-CoV-2
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