Intra-orbital Castleman's disease.

Castleman's disease is a rare lymphoproliferative process found in either a focal or multicentric localization. Most cases occur as mediastinal and abdominal mass, although nodal and extranodal locations have been reported. Eleven cases of Castleman's disease involving the central nervous system have been reported, but only one is a proven instance of primary intra-orbital localization. The present report concerns a clinico-pathologic Castleman's disease case, to our knowledge the second orbital case described in the literature.