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5.
An Med Interna ; 23(2): 73-6, 2006 Feb.
Article in Spanish | MEDLINE | ID: mdl-16566655

ABSTRACT

Pulmonary Langerhans'-cell histiocytosis belongs to a spectrum of diseases characterized by monoclonal proliferation and infiltration of organs by Langerhans' cells. It is an uncommon interstitial lung disease of unknown etiology occurring almost exclusively in cigarette smokers. It s course in adults is variable and unpredictable, ranging from benign self-limiting types with spontaneous regression to slowly progressive malignant disease that leads to respiratory failure and death. We report one patient diagnoses of pulmonary Langerhans' cell histiocytosis who experimented an objective radiographic improvement and disappearance of symptoms after smoking cessation.


Subject(s)
Histiocytosis, Langerhans-Cell/diagnosis , Adult , Humans , Lung/diagnostic imaging , Lung/pathology , Male , Radiography , Remission, Spontaneous , Smoking Cessation
6.
An. med. interna (Madr., 1983) ; 23(2): 73-76, feb. 2006. ilus, tab
Article in Es | IBECS | ID: ibc-044410

ABSTRACT

La histiocitosis pulmonar de células de Langerhans forma parte de un espectro de enfermedades caracterizadas por la proliferación monoclonal y la infiltración de distintos órganos por células de Langerhans. Es una enfermedad pulmonar intersticial de etiología desconocida que ocurre casi exclusivamente en pacientes fumadores. El curso de esta enfermedad en adultos es impredecible, oscilando desde formas benignas autolimitadas, hasta formas malignas con evolución progresiva hacia el fallo respiratorio y la muerte. Presentamos el caso de un paciente diagnosticado de histiocitosis pulmonar de células de Langerhans que presentó una mejoría clínica y radiográfica tras abandonar el hábito tabáquico


Pulmonary Langerhans´- cell histiocytosis belongs to a spectrum of diseases characterized by monoclonal proliferation and infiltration of organs by Langerhans´cells. It is an uncommon interstitial lung disease of unknown etiology occurring almost exclusively in cigarette smokers. It´s course in adults is variable and unpredictable, ranging from benign self-limiting types with spontaneous regression to slowly progressive malignant disease that leads to respiratory failure and death. We report one patient diagnoses of pulmonary Langerhans´cell histiocytosis who experimented an objetive radiographic improvement and disappearance of symptoms after smoking cessation


Subject(s)
Male , Adult , Humans , Histiocytosis, Langerhans-Cell/pathology , Histiocytosis, Langerhans-Cell/etiology , Tobacco Use Disorder/complications , Tomography, X-Ray Computed
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