ABSTRACT
CASO CLÍNICO: Varón de 21 años con historia de exoftalmos izquierdo y diplopía de 2 semanas de evolución. La resonancia magnética mostró una lesión muy vascularizada etmoido-orbitaria con invasión de base del cráneo anterior y extensión orbitaria. La biopsia etmoidal confirmó un tejido fibrovascular compatible con angiofibroma. DISCUSIÓN: El angiofibroma nasofaríngeo juvenil (ANJ) es un tumor benigno con características locales de malignidad debido a su capacidad de invadir áreas adyacentes. En nuestro caso, el comienzo se presenta con manifestaciones de extensión orbitaria. Consideramos necesario un conocimiento amplio y un abordaje multidisciplinario con el fin de mejorar el pronóstico
CLINICAL CASE: The case is presented of a 21 year-old male with a history of left proptosis and diplopia of two weeks of onset. The MRI showed an ethmoid-orbital vascular lesion with anterior skull base invasion and orbital extension. Biopsy of the ethmoid confirmed fibrovascular tissue, which supported the diagnosis of angiofibroma. DISCUSSION: It is a benign neoplasm with local characteristics of malignancy due to its ability to invade adjacent areas. In this case, the debut presented with manifestations of orbital extension. A broad and multidisciplinary approach is needed in order to improve prognosis
Subject(s)
Humans , Male , Young Adult , Angiofibroma/chemically induced , Angiofibroma/pathology , Nasopharyngeal Neoplasms/chemically induced , Nasopharyngeal Neoplasms/pathology , Eye Neoplasms/drug therapy , Eye Neoplasms/radiotherapy , Exophthalmos/congenital , Exophthalmos/metabolism , Head and Neck Neoplasms/diagnosis , Angiofibroma/diagnosis , Angiofibroma/prevention & control , Nasopharyngeal Neoplasms/diagnosis , Nasopharyngeal Neoplasms/metabolism , Eye Neoplasms/complications , Eye Neoplasms/surgery , Exophthalmos/complications , Exophthalmos/surgery , Head and Neck Neoplasms/drug therapyABSTRACT
CLINICAL CASE: The case is presented of a 21 year-old male with a history of left proptosis and diplopia of two weeks of onset. The MRI showed an ethmoid-orbital vascular lesion with anterior skull base invasion and orbital extension. Biopsy of the ethmoid confirmed fibrovascular tissue, which supported the diagnosis of angiofibroma. DISCUSSION: It is a benign neoplasm with local characteristics of malignancy due to its ability to invade adjacent areas. In this case, the debut presented with manifestations of orbital extension. A broad and multidisciplinary approach is needed in order to improve prognosis.
Subject(s)
Angiofibroma/pathology , Nasopharyngeal Neoplasms/pathology , Orbit/pathology , Angiofibroma/diagnostic imaging , Angiofibroma/radiotherapy , Angiofibroma/surgery , Biopsy , Cerebral Angiography , Combined Modality Therapy , Diplopia/etiology , Ethmoid Bone/diagnostic imaging , Ethmoid Bone/pathology , Exophthalmos/etiology , Humans , Magnetic Resonance Imaging , Male , Maxillary Artery/diagnostic imaging , Nasopharyngeal Neoplasms/diagnostic imaging , Nasopharyngeal Neoplasms/radiotherapy , Nasopharyngeal Neoplasms/surgery , Neoplasm Invasiveness , Ophthalmic Artery/diagnostic imaging , Orbit/diagnostic imaging , Skull Base/diagnostic imaging , Skull Base/pathology , Young AdultABSTRACT
Presentation of an uncommon form of distant primary dissemination of renal adenocarcinoma (RA) 5 years after radical surgery, the subcutaneous metastasis. The patient underwent surgical resection of metastasis, and later developed early pulmonary, mediastinal and new skin metastasis. A review is made of the incidence, therapeutical approach and prognostic value of skin metastasis due to RA.
Subject(s)
Adenocarcinoma/secondary , Kidney Neoplasms/pathology , Skin Neoplasms/secondary , Adenocarcinoma/pathology , Adenocarcinoma/surgery , Humans , Kidney Neoplasms/surgery , Lung Neoplasms/secondary , Lymphatic Metastasis , Male , Mediastinal Neoplasms/secondary , Middle Aged , Nephrectomy , Skin Neoplasms/diagnosis , Skin Neoplasms/surgery , Thorax , Time FactorsABSTRACT
Verrucous carcinoma includes approximately 5% of all neoplasias of the penis and is a tumoral variety of benign behaviour and differentiated histology. Our 10-case experience of penial verrucous carcinoma is reported here. In nearly all cases, partial penectomy was the definitive approach. No dissemination, locorregional or distant, was found in any of the report cases. Since prognosis of these tumours is good, we see no justification in performing lymphadenectomy, although it is advisable to adopt and expectant attitude when faced to inguinal adenopathies.
Subject(s)
Carcinoma, Verrucous/pathology , Penile Neoplasms/pathology , Aged , Aged, 80 and over , Carcinoma, Verrucous/surgery , Humans , Male , Middle Aged , Penile Neoplasms/surgeryABSTRACT
We describe a patient with giant cell carcinoma with ectopic production of chorionic gonadotrophin hormone (CGH). This entity is compared with choriocarcinoma, given that the immunologic, histologic and chemical similarities between the two neoplasms can make their anatomic and pathologic differential diagnosis difficult. Clinical examination, response to treatment and CGH blood levels are the criteria for differentiation.
Subject(s)
Carcinoma, Large Cell/diagnosis , Carcinoma, Large Cell/metabolism , Choriocarcinoma/diagnosis , Chorionic Gonadotropin/metabolism , Lung Neoplasms/diagnosis , Lung Neoplasms/metabolism , Carcinoma, Large Cell/pathology , Carcinoma, Large Cell/surgery , Chemotherapy, Adjuvant , Diagnosis, Differential , Fatal Outcome , Humans , Lung Neoplasms/pathology , Lung Neoplasms/surgery , Male , Middle Aged , PneumonectomyABSTRACT
Cancer of scrotum is of interest, despite its relative infrequency, because of its historical importance (was the first known occupational cancer) and also of its aggressive behavior. We report a rare case of verrucous carcinoma in a 67 years old man, without recrudescence six months after surgical treatment.
