ABSTRACT
We studied 5 children with intestinal malakoplakia who were seen during a period of 10 years. Four were male and one female. The main clinical manifestations were: chronic bloody and mucous diarrhea, abdominal pain and polypoid masses detected by rectal maneuver. Either the radiological study as well as endoscopy showed the presence of stenosis and polypoid masses (pseudopolyps). Two patients underwent laparotomy and a tumoral infiltration at the level of rectal-sigmoid and cecal appendix was found. Histological diagnosis proves to be definitive in these case. Drug treatment has been with bethanechol, trimethoprim-sulfamethoxazole in three patients. We conclude that intestinal malakoplakia is more common that ulcerative colitis in our children population attending at this institute. Therefore, the presence of intestinal malakoplakia must be ruled out in every child having chronic bloody and mucous diarrhea, presenting as well pseudopolyps.
Subject(s)
Intestinal Diseases , Malacoplakia , Adolescent , Child , Child, Preschool , Female , Humans , Intestinal Diseases/complications , Intestinal Diseases/diagnosis , Intestinal Diseases/drug therapy , Intestinal Diseases/microbiology , Malacoplakia/complications , Malacoplakia/diagnosis , Malacoplakia/drug therapy , Malacoplakia/microbiology , MaleABSTRACT
Esophageal strictures may complice Dystrophic Recessive + Epidermolysis Bullosa (DREB). We report six consecutive cases of DREB with this type of lesion as the main gastrointestinal manifestation. In three children the stenosis was unique and located in the upper third one in the middle third, and the last two children showed a double stenosis (Upper and middle third) of the esophagus.
Subject(s)
Epidermolysis Bullosa Dystrophica/complications , Esophageal Stenosis/etiology , Adolescent , Child , Epidermolysis Bullosa Dystrophica/classification , Female , Genes, Recessive , Humans , MaleABSTRACT
The clinical charts of eight children with gastrointestinal symptomatology secondary to recessive dystrophic epidermolysis bullosa are reviewed. The most frequently found gastrointestinal lesions were esophageal stricture (6 patients), a repeated history of ampullar lesions (8 patients), constipation (5) and anchiloglossia (2). The most frequent and feared lesion is the esophageal stricture. Esophageal stricture; epidermolysis; gastrointestinal manifestations.
Subject(s)
Epidermolysis Bullosa/complications , Gastrointestinal Diseases/etiology , Child , Child, Preschool , Epidermolysis Bullosa/genetics , Esophageal Stenosis/etiology , Female , Genes, Recessive , Humans , Male , Mucous MembraneABSTRACT
In this article, the neurophysiology and neurobiochemistry of the digestive system are reviewed briefly. The pharmacology of the main gastrointestinal prokinetic drugs and their indications, side effects and dosages in pediatric patients are described.
Subject(s)
Bethanechol Compounds/pharmacology , Gastrointestinal Motility/drug effects , Tropanes/pharmacology , Bethanechol , Gastrointestinal Motility/physiology , Humans , Neurotransmitter Agents/physiologySubject(s)
Gastroesophageal Reflux/diagnosis , Hydrogen-Ion Concentration , Adolescent , Child , Child, Preschool , Esophagus , Humans , Infant , Infant, NewbornABSTRACT
A case of antral membrane in a 23 month old child is presented. He developed an extremely rapid clinical course characterized by vomiting, 4 kg weight loss and acute malnutrition. The UGI showed a probable antropyloric obstruction which was confirmed by endoscopy and lately by surgery. It is suggested that in the approach of a patient with vomit it is very important to make an oriented clinical history and always complete the study of the patients with radiological and endoscopic procedures.
Subject(s)
Pyloric Antrum/abnormalities , Gastroscopy , Humans , Infant , Male , Pyloric Antrum/diagnostic imaging , Pyloric Antrum/physiopathology , RadiographyABSTRACT
The indications for liver transplantation in children as well as its contraindications are reviewed and analyzed. We describe the basis for a correct receptor and donor selection. The cost and complications of the procedure are discussed.
