ABSTRACT
En este artículo se ha realizado una revisión sistemática de los aspectos prácticos más destacables del manejo del traumatismo craneoencefálico en base a la literatura médica que hemos considerado relevante. El trabajo se ha desarrollado en diferentes apartados que comprenden la epidemiología, pronóstico y clasificación, anatomía patológica y fisiopatología, evaluación clínica y tratamiento. Se han tratado con especial énfasis las conexiones entre los rasgos fisiopatológicos con mayor grado de evidencia, de acuerdo con las guías de práctica clínica, y los esquemas de manejo terapéutico (AU)
A systematic revision of the main practical aspects related with the head injury management has been made in this article on the basis of relevant literature. The paper has been developed in different sections consisting of epidemiological factors, prognosis and classification, neuropathology and pathophysiology, clinical evaluation and treatment. According to clinical guidelines, the connections between the pathophysiological features with higher evidence degree and the schemes of therapeutic approahes have been emphasized (AU)
Subject(s)
Female , Humans , Male , Head Injuries, Penetrating/cerebrospinal fluid , Head Injuries, Penetrating/physiopathology , Diffuse Axonal Injury/cerebrospinal fluid , Diffuse Axonal Injury/metabolism , Cerebral Infarction/blood , Cerebral Infarction/genetics , Neurons/cytology , Necrosis/surgery , Head Injuries, Penetrating/complications , Head Injuries, Penetrating/metabolism , Diffuse Axonal Injury/pathology , Diffuse Axonal Injury/psychology , Cerebral Infarction/complications , Cerebral Infarction/physiopathology , /standards , Neurons/pathology , Necrosis/complicationsABSTRACT
A systematic revision of the main practical aspects related with the head injury management has been made in this article on the basis of relevant literature. The paper has been developed in different sections consisting of epidemiological factors, prognosis and classification, neuropathology and pathophysiology, clinical evaluation and treatment. According to clinical guidelines, the connections between the pathophysiological features with higher evidence degree and the schemes of therapeutic approaches have been emphasized.
Subject(s)
Craniocerebral Trauma , Brain Damage, Chronic/etiology , Brain Damage, Chronic/prevention & control , Brain Edema/etiology , Brain Injuries/diagnosis , Brain Injuries/etiology , Brain Injuries/metabolism , Brain Injuries/physiopathology , Brain Injuries/rehabilitation , Brain Injuries/surgery , Cell Death , Cerebrovascular Circulation , Craniocerebral Trauma/classification , Craniocerebral Trauma/complications , Craniocerebral Trauma/diagnosis , Craniocerebral Trauma/epidemiology , Craniocerebral Trauma/physiopathology , Critical Care/methods , Diagnostic Imaging/methods , Disease Management , Emergency Medical Services/methods , Energy Metabolism , Glasgow Coma Scale , Humans , Intracranial Hypertension/etiology , Intracranial Hypertension/therapy , Monitoring, Physiologic/methods , Neurologic Examination , Neurons/metabolism , Neurons/pathology , Neurosurgical Procedures , PrognosisABSTRACT
We report a case of radiation-induced sarcoma in a 50 year-old male patient who was treated with total resection and radiation for right temporal lobe PNET. He received a dose of 60-Gy. A sequential magnetic resonance image 32 months after the completion of radiation therapy and 34 months after surgery showed a mass in the right temporal cerebral convexity. The postoperative diagnosis was sarcoma. Two years later the patient was operated because of a new lesion with similar characteristics. The follow up from the PNET diagnosis is 5 years and 10 months and the survival from sarcoma diagnosis is now 3 years and there is no evidence of recurrence. The development of sarcoma subsequent to cranial irradiation is an infrequent event but it should be considered in the differential diagnosis of a lesion that progresses several years after radiation therapy or when a new lesion appear.
