ABSTRACT
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Subject(s)
Female , Humans , Adult , Streptococcus sanguis , Gram-Positive Bacterial Infections , Enterococcus faecalis , Hydropneumothorax , Immunocompetence , Pneumonia, Bacterial , Streptococcal InfectionsABSTRACT
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Subject(s)
Adult , Male , Humans , Embryo Research , Stem Cell Transplantation , Schizophrenia , Antipsychotic Agents , Neuroleptic Malignant Syndrome , Catatonia , Diagnosis, Differential , HaloperidolABSTRACT
The acute respiratory distress syndrome (ARDS) is a rare but serious complication of miliary tuberculosis with a mortality rate near 100% when associated with pancytopenia. This association has been rarely reported (eleven cases in a Medline search, 1966-1999). A case is here reported of an HIV-negative patient with miliary tuberculosis which presented as ARDS associated with pancytopenia. This case prompted us to review the literature and risk factors, diagnosis and treatment issues are discussed. In patients with predisposing factors miliary tuberculosis must be considered as a possible cause of ARDS.
Subject(s)
HIV Seronegativity , Pancytopenia/complications , Respiratory Distress Syndrome/complications , Tuberculosis, Miliary/complications , Adolescent , Humans , MaleABSTRACT
BACKGROUND: Although the pathogenic role of Coxiella burnetii infection during pregnancy is controversial, some cases of stillbirth and abortion occurring after an acute or chronic infection have been mentioned in the literature. Recently, Q fever has been advocated as a significant cause of morbidity and mortality in pregnancy CASE: We describe an 18-year-old primipara woman admitted to our hospital for high fever and pancytopenia during an acute C. burnetii infection. She was successfully treated with clarithromycin, overcoming fever and pancytopenia. Finally, she gave birth to a healthy infant, and 1 year later both remained well. CONCLUSION: Q fever is a potentially serious disease in pregnancy owing to the possibility of placenta infection and fetal transmission affecting its outcome. Q fever infection should be suspected in unexplained febrile episodes or abortion during pregnancy, when epidemiologic and clinical data are present. We believe that C. burnetii serology should be tested in cases of fever of known origin or unexplained abortions, as the TORCH infections are.
Subject(s)
Coxiella burnetii/isolation & purification , Pregnancy Complications, Infectious/microbiology , Q Fever/complications , Abortion, Spontaneous/microbiology , Adolescent , Anti-Bacterial Agents/therapeutic use , Clarithromycin/therapeutic use , Female , Humans , Infant, Newborn , Obstetric Labor, Premature/microbiology , Pancytopenia/drug therapy , Pancytopenia/microbiology , Pregnancy , Pregnancy Outcome , Q Fever/drug therapyABSTRACT
El síndrome de distrés respiratorio agudo (SDRA) es una complicación rara pero muy grave de la tuberculosis miliar que cuando se asocia a pancitopenia se acerca a una mortalidad del 100 por ciento. Esta asociación ha sido escasamente descrita (11 casos en revisión Medline, 1966-1999).Presentamos el caso de 1 paciente VIH negativo con una tuberculosis miliar que comienza como un SDRA, al que se asocia pancitopenia. A propósito del mismo se revisa la literatura, describiéndose los factores de riesgo, diagnóstico y tratamiento. Es fundamental considerar la tuberculosis como etiología posible en pacientes con factores de riesgo que presentan SDRA (AU)
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