Task Similarity Estimation Through Adversarial Multitask Neural Network.

Multitask learning (MTL) aims at solving the related tasks simultaneously by exploiting shared knowledge to improve performance on individual tasks. Though numerous empirical results supported the notion that such shared knowledge among tasks plays an essential role in MTL, the theoretical understanding of the relationships between tasks and their impact on learning shared knowledge is still an open problem. In this work, we are developing a theoretical perspective of the benefits involved in using information similarity for MTL. To this end, we first propose an upper bound on the generalization error by implementing the Wasserstein distance as the similarity metric. This indicates the practical principles of applying the similarity information to control the generalization errors. Based on those theoretical results, we revisited the adversarial multitask neural network and proposed a new training algorithm to learn the task relation coefficients and neural network parameters automatically. The computer vision benchmarks reveal the abilities of the proposed algorithms to improve the empirical performance. Finally, we test the proposed approach on real medical data sets, showing its advantage for extracting task relations.

A machine learning approach for online automated optimization of super-resolution optical microscopy.

Traditional approaches for finding well-performing parameterizations of complex imaging systems, such as super-resolution microscopes rely on an extensive exploration phase over the illumination and acquisition settings, prior to the imaging task. This strategy suffers from several issues: it requires a large amount of parameter configurations to be evaluated, it leads to discrepancies between well-performing parameters in the exploration phase and imaging task, and it results in a waste of time and resources given that optimization and final imaging tasks are conducted separately. Here we show that a fully automated, machine learning-based system can conduct imaging parameter optimization toward a trade-off between several objectives, simultaneously to the imaging task. Its potential is highlighted on various imaging tasks, such as live-cell and multicolor imaging and multimodal optimization. This online optimization routine can be integrated to various imaging systems to increase accessibility, optimize performance and improve overall imaging quality.