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1.
Rev. cir. (Impr.) ; 74(4): 421-425, ago. 2022. ilus
Article in Spanish | LILACS | ID: biblio-1407930

ABSTRACT

Resumen Objetivo: Reportar el caso de una paciente con intususcepción apendicular (IA), condición infrecuente, secundario a foco de endometriosis, patología que en los últimos años ha presentado un aumento en su incidencia. Material y Método: Historia clínica, imágenes preoperatorias e intraoperatorias obtenidas de la ficha clínica. Resultados: Mujer de 35 años con dolor abdominal crónico de 4 meses de evolución. Se realiza estudio colonoscópico evidenciando lesión de 15 x 8 mm en ostium apendicular intususceptada al lumen cecal, y enteroclisis por tomografía axial computarizada (TC) que confirma IA. Se realiza una resección ileocecal laparoscópica demostrando la invaginación del apéndice con biopsia que muestra un foco de endometrioma. Discusión: La IA es una condición infrecuente con una incidencia cercana al 0,01% en la población general. Las patologías benignas son la principal causa (77%), siendo la endometriosis la causa más frecuente. Conclusión: La IA por endometriosis es anecdótica, con sintomatología poco específica. Los estudios disponibles pueden orientar adecuadamente la presencia de IA, sin embargo, en algunas ocasiones puede confundirse con patologías neoplásicas, donde cobra importancia la cirugía para dilucidar la etiología.


Objective: To report the case of a patient with appendicular intussusception (AI), an infrequent condition secondary to a focus of endometriosis, a pathology that has increased incidence in recent years. Material and Method: Clinical case, history and images obtained from the clinical file and intraoperative records with the consent of the patient. Results: A 35-year-old woman with abdominal pain. Colonoscopy study showing a 15 × 8 mm lesion in the appendicular ostium intussuscepted to the cecal lumen, and a computerized tomography (CT) enteroclysis confirming AI. A laparoscopic ileocecal resection is performed, demonstrating invagination of the appendix secondary to an endometrioma focus. Discussion: AI is a rare condition, with an incidence close to 0.01% in the general population. Benign pathologies are the main cause (77%), endometriosis being the most frequent cause. Conclusion: AI due to endometriosis is anecdotal, with unspecific symptoms. The available studies can adequately guide the presence of AI, however, on some occasions it can be confused with neoplastic pathologies, where surgery is important to elucidate the etiology.


Subject(s)
Humans , Female , Adult , Appendix/pathology , Cecal Diseases/etiology , Endometriosis/complications , Intussusception/etiology , Tomography, X-Ray Computed , Cecal Diseases/diagnosis , Colonoscopy , Endometriosis/diagnosis , Intussusception/diagnosis
4.
Gastroenterol. latinoam ; 27(4): 207-214, 2016. ilus, tab
Article in Spanish | LILACS | ID: biblio-907638

ABSTRACT

Introduction: Gastric cancer (GC) is the leading cause of cancer mortality in Chile. The development ofgastric adenocarcinoma its preceded by a histopathologic cascade composed of gastric atrophy, intestinal metaplasia and gastric dysplasia. Sydney protocol has been proposed as the standard method for diagnosingthese conditions. The aim of this research study was to establish whether Sydney protocol increase thedetection of premalignant gastric lesions, as gastric atrophy and intestinal metaplasia, compared to non protocolizedendoscopies/biopsies. Methods: Upper gastroduodenal endoscopies (GDE) from Hospital Clí-nico Universidad Católica de Chile between April-May 2015 and April-May 2016 was analyzed. Patientswith histological study with 18 years-old or older were included. Patients with history of GC or malignantlesions at GDE where excluded. Detection of gastric atrophy, intestinal metaplasia and suggestive findingsof autoimmune gastritis where compared between Sydney protocol and non-protocolized endoscopies/biopsies...


Introducción: El cáncer gástrico (CG) es la principal causa de muertes por cáncer en Chile. El desarrollo del adenocarcinoma gástrico es precedido por una cascada histopatológica (gastritis; atrofia gástrica/AG; metaplasia intestinal/MI). Se ha propuesto la biopsia del cuerpo, ángulo y antro a través del protocolo de Sydney para la búsqueda de estas condiciones. Objetivo: Determinar la diferencia en la detección delesiones premalignas gástricas a través del protocolo de Sydney comparado con el estudio endoscópico habitual. Métodos: Se analizaron las endoscopias digestivas altas (EDA) realizadas en el Centro de Endoscopia Digestiva del Hospital Clínico de la Universidad Católica en los períodos entre abril y mayo del 2015 y 2016. Se incluyeron las EDA de pacientes mayores de 18 años con estudio histológico. Fueron excluidos los pacientes con antecedente personal de CG o lesiones de aspecto maligno macroscópicas. Se comparó la detección de AG, MI y gastritis autoinmune (GA) en el estudio histológico entre los pacientes con protocolo Sydney y el estudio endoscópico no protocolizado...


Subject(s)
Male , Female , Humans , Adult , Young Adult , Middle Aged , Aged , Aged, 80 and over , Biopsy/methods , Precancerous Conditions/pathology , Stomach Neoplasms/pathology , Atrophy/pathology , Chile , Clinical Protocols , Endoscopy, Digestive System , Helicobacter Infections/pathology , Metaplasia/pathology , Retrospective Studies
5.
ISA Trans ; 58: 389-97, 2015 Sep.
Article in English | MEDLINE | ID: mdl-25997372

ABSTRACT

Partial discharges measurement is one of the most useful tools for condition monitoring of high-voltage (HV) equipment. These phenomena can be measured on-line in radiofrequency (RF) with sensors such as the Vivaldi antenna, used in this paper, which improves the signal-to-noise ratio by rejecting FM and low-frequency TV bands. Additionally, the power ratios (PR), a signal-processing technique based on the power distribution of the incoming signals in frequency bands, are used to characterize different sources of PD and electromagnetic noise (EMN). The calculation of the time length of the pulses is introduced to separate signals where the PR alone do not give a conclusive solution. Thus, if several EM sources could be previously calibrated, it is possible to detect pulses corresponding to PD activity.

7.
Artrosc. (B. Aires) ; 20(4): 122-125, dic. 2013.
Article in Spanish | LILACS | ID: lil-743154

ABSTRACT

El posicionamiento anatómico de los túneles en cirugía de ligamento cruzado anterior, ha sido sugerido como una estrategia para reducir la inestabilidad rotacional y por tanto la artrosis futura. Las técnicas más comunes utilizadas para posicionar el túnel femoral son: la técnica transtibial y la técnica de portal anteromedial. Ha sido reportado que un posicionamiento anatómico del túnel femoral es imposible mediante la técnica transtibial, incluso con modificaciones. Por otra parte, la técnica de portal anteromedial si bien logra un posicionamiento más anatómico del túnel femoral, puede resultar en un túnel más corto, además de la posibilidad de causar daño al cartílago articular del cóndilo femoral medial durante el proceso de realización de este; y por último, existe el riesgo de dañar las estructuras neurovasculares al pasar las guías y brocas de medial a lateral. En un esfuerzo por ir mejorando las técnicas quirúrgicas disponibles, se ha desarrollado la técnica de túnel femoral retrogrado o retroconstrucción, la cual lograría posicionar un túnel femoral anatómico evitando las complicaciones de la técnica de portal anteromedial. En este artículo, presentaremos la técnica de Retroconstrucción de LCA con autoinjerto semitendinoso-gracillis, utilizando el instrumental FlipCutterTM (Arthrex Inc, Naples) con método de fijación femoral suspensorio Tight RopeTM (Arthrex Inc, Naples) y fijación tibial con tornillo interferencial BiocompositeTM (Arthrex Inc, Naples).


The anatomical positioning of tunnels in Anterior Cruciate Ligament (ACL) surgery has been suggested as a strategy to reduce rotational instability and osteoarthritis. Usual techniques used to make the femoral tunnel are the transtibial technique and the anteromedial portal technique. It has been reported that it is impossible to make an anatomical femoral tunnel using the transtibial technique, even with variations. Furthemore, the anteromedial portal technique can locate a more anatomical tunnel but has complications like short tunnel, damage to the medial femoral condyle and risks for the lateral neurovascular bundle. In an effort to improve our capacity of positioning an anatomical femoral tunnel with less complications, the retroconstruction technique has been developed. In this article we present the ACL retroconstruction technique using autologous semitendinous-gracillis graft with FlipCutterTM (Arthrex Inc, Naples).


Subject(s)
Humans , Knee Joint/surgery , Anterior Cruciate Ligament/surgery , Minimally Invasive Surgical Procedures , Anterior Cruciate Ligament Reconstruction/methods , Tendons/transplantation , Transplantation, Autologous/methods
8.
Gastroenterol. latinoam ; 24(supl.1): S98-S101, 2013. ilus
Article in Spanish | LILACS | ID: lil-763734

ABSTRACT

Acute pancreatitis is a disease that presents heterogeneously with varying severity depending on pancreatic parenchyma and peripancreatic fat. The aim of this publication is to present the nomenclature in use in the different collections that develop in the evolution of acute pancreatitis, and management options of these collections, focusing on the management of infected pancreatic necrosis; emphasizing the benefits, results and limitations of each technique and describing some techniques under development.


La pancreatitis aguda es una enfermedad que se presenta en forma heterogénea con distinta gravedad según el compromiso del parénquima pancreático y de la grasa peripancreática. El objetivo de esta publicación es dar a conocer la nomenclatura en uso en las distintas colecciones que se manifiestan en la evolución de la pancreatitis aguda y las opciones de manejo de estas colecciones, enfocándose en el manejo de la necrosis pancreática infectada; enfatizando las ventajas, resultados y limitaciones de cada técnica, además de describir algunas técnicas en desarrollo.


Subject(s)
Humans , Drainage/methods , Necrosis/therapy , Pancreatitis, Acute Necrotizing/therapy , Necrosis/surgery , Pancreatitis, Acute Necrotizing/surgery , Digestive System Surgical Procedures/methods
9.
Transbound Emerg Dis ; 59(2): 183-8, 2012 Apr.
Article in English | MEDLINE | ID: mdl-21801341

ABSTRACT

A cross-sectional study was conducted to evaluate the transmission of swine influenza through occupational exposure and to assess some risk factors for zoonotic transmission in workers from commercial farms in Mexico. Seroprevalence to swine influenza subtypes was determined by hemagglutinin inhibition assay and was higher in exposed (E), in comparison with unexposed (UE) participants (P<0.05). Percentages of seropositivity between UE and E were 28.57% and 19.35% to A/NewCaledonia/20/99 (H1N1), 68.25% and 33.87% to A/Panama/2001/99-like (H3N2), 1.58% and 12.9% to A/Sw/England/163266/87 (H3N2), respectively. No antibodies were detected against A/Sw/Wisconsin/238/97 (H1N1) in the UE subjects, and only 3.22% were positive in the E group (P<0.05). A significant association between elevated antibody titres to swine influenza virus (SIV) H3N2 and the exposition to swine [OR 3.05, 95% (CI) 1.65-5.64] and to geographic location [OR 8.15, 95% (CI) 1.41-47.05] was found. Vaccination appeared as a protective factor [OR 0.05, 95% (CI) 0.01-0.52]. Farms with high number of breeding herd were associated with increased anti-SIV antibodies in the E group [OR 3.98, 95% (CI) 1.00-15.86]. These findings are relevant and support the evidence of zoonoses in swine farms and point out the need to implement preventive measures to diminish the occurrence of the disease and the potential emergence of pathogenic reassortant strains.


Subject(s)
Influenza, Human/virology , Orthomyxoviridae Infections/veterinary , Swine Diseases/virology , Zoonoses , Animals , Antibodies, Viral , Cross-Sectional Studies , Humans , Influenza, Human/epidemiology , Influenza, Human/transmission , Mexico/epidemiology , Orthomyxoviridae Infections/transmission , Orthomyxoviridae Infections/virology , Risk Factors , Seroepidemiologic Studies , Swine , Swine Diseases/epidemiology
10.
Fam. aten. prim ; 9(3): 81-84, Dic. 2011. ilus
Article in Spanish | IBECS | ID: ibc-106484

ABSTRACT

Una de las principales barreras que impiden la mejora de la práctica clínica y los resultados en salud es el fallo en la transmisión del conocimiento científico a la práctica clínica. En estudios previos se ha mostrado la estrategia outreach visits, eficaz para modificar la conducta de los profesionales sanitarios.Desde la Oficina de Evaluación de Medicamentos decidimos impulsar esta estrategia para difundir el sistema de recomendaciones GRADE (Grading of Recommendations Assessment, Development and Evaluation) e información farmacoterapéutica. Cada farmacéutico intervino con médicos de su equipo de atención primaria, siguiendo un procedimiento previamente entrenado. Además, se entregó a los médicos un cuestionario anónimo para conocer su opinión sobre la utilidad del sistema de recomendaciones GRADE y si la intervención le aporta conocimiento sobre el fármaco. Según los resultados, el 86% de los médicos opina que la visita le añadió conocimiento sobre el fármaco y el 93% piensa que las recomendaciones GRADE añaden utilidad clínica para el manejo del fármaco (AU)


One of the main barriers to improving clinical practice and health outcomes is the failure in the transmission of scientific knowledge to the clinical practice. Previous studies have shown that the outreach visits strategy is effective as an educational strategy to change the behavior of health care professionals. Therefore, the Oficina de Evaluación de Medicamentos (Medicinal Produce Evaluation Office) has decided to promote an outreach visits strategy to disseminate GRADE recommendations and pharmacotherapeutical information. Each pharmacist intervened with the physicians following a previously trained procedure. These physicians were also given an anonymous questionnaire in order to know their opinion about the usefulness of the GRADE recommendations and if the intervention provides knowledge about the drug. According to the results, 86% of physicians believe that the visit added knowledge regarding the drug and 93% consider that the GRADE recommendations add clinical useful for the drug management (AU)


Subject(s)
Humans , Education, Medical, Continuing/trends , Education, Pharmacy, Continuing/trends , Drug Evaluation , Pharmacy Service, Hospital/organization & administration , Clinical Pharmacy Information Systems/organization & administration , 24419
11.
Rev. chil. cir ; 63(1): 59-63, feb. 2011. ilus, tab
Article in Spanish | LILACS | ID: lil-582947

ABSTRACT

Background: Colorectal colectomy is a less invasive technique that can be used for the treatment of diverticular disease, recently in younger patients. Aim: To report the experience with laparoscopic colectomy for diverticular disease. Material and Methods: All patients with indication for elective surgical resolution for diverticular disease were subjected to laparoscopic surgery from 1997 to 2009. The surgical protocols of these patients were analyzed. Results: Sixty patients with average age 53,8 (31 males) were operated in the period. Forty six were subjected to a sigmoidectomy and 14 to left hemicolectomy. Operative average time was 173 minutes and hospital stay 4,16 days. Three patients had to be converted to open surgery and three had complications that were managed without need of reoperation. During a median follow up of 38 months, the disease relapsed in two patients, which did not require a new intervention. Conclusions: Elective laparoscopic colectomy for diverticular disease is feasible and safe.


La cirugía laparoscópica colorrectal, aunque de desarrollo lento, ha presentado en los últimos años ventajas con respecto a la cirugía abierta. Hay escasas publicaciones nacionales sobre esta técnica en enfermedad diverticular. Objetivo: Presentar nuestra experiencia en enfermedad diverticular en una serie consecutiva de pacientes con indicación quirúrgica electiva resueltos por vía laparoscópica. Material y Método: Se analizan los protocolos prospectivos de cirugía laparoscópica de colon con diagnóstico de enfermedad diverticular para resolución electiva, desde junio de 1997, hasta diciembre de 2009. Todo paciente con indicación quirúrgica electiva por esta patología fue resuelto por vía laparoscópica. Se estudian edad, sexo, tipo de resección, evolución postoperatoria inmediata y tardía. Resultados: Se operaron 60 pacientes, con edad promedio de 53,8 años. De éstos 46 fueron sigmoidectomías y 14 hemicolectomías izquierdas. El tiempo operatorio promedio fue de 173 minutos y la hospitalización de 4,16 días. Se convirtieron 3 pacientes (5 por ciento) y hubo 3 complicaciones (5 por ciento), que fueron manejadas médicamente. Hubo 1 estenosis de anastomosis tratada endoscópicamente como complicación tardía. Seguimiento promedio de 37,9 meses. Hubo 2 recidivas (3,3 por ciento), tratadas médicamente y no hubo mortalidad en esta serie. Conclusión: La cirugía laparoscópica para la enfermedad diverticular electiva es factible de realizar en la gran mayoría de los pacientes, con baja morbilidad y rápida recuperación.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Colectomy/methods , Diverticulum, Colon/surgery , Sigmoid Diseases/surgery , Laparoscopy , Elective Surgical Procedures , Follow-Up Studies , Length of Stay , Prospective Studies
12.
Transbound Emerg Dis ; 58(1): 63-8, 2011 Feb.
Article in English | MEDLINE | ID: mdl-21091641

ABSTRACT

A two-year survey was carried out on the occurrence of avian influenza in migrating birds in two estuaries of the Mexican state of Sonora, which is located within the Pacific flyway. Cloacal and oropharyngeal swabs were collected from 1262 birds, including 20 aquatic bird species from the Moroncarit and Tobari estuaries in Sonora, Mexico. Samples were tested for type A influenza (M), H5 Eurasian and North American subtypes (H5EA and H5NA respectively) and the H7 North American subtype (H7NA). Gene detection was determined by one-step real-time reverse transcription polymerase chain reaction (RRT-PCR). The results revealed that neither the highly pathogenic avian influenza virus H5 of Eurasian lineage nor H7NA were detected. The overall prevalence of avian influenza type A (M-positive) in the sampled birds was 3.6% with the vast majority in dabbling ducks (Anas species). Samples from two birds, one from a Redhead (Aythya americana) and another from a Northern Shoveler (Anas clypeata), were positive for the low-pathogenic H5 avian influenza virus of North American lineage. These findings represented documented evidence of the occurrence of avian influenza in wintering birds in the Mexican wetlands. This type of study contributes to the understanding of how viruses spread to new regions of North America and highlights the importance of surveillance for the early detection and control of potentially pathogenic strains, which could affect animal and human health.


Subject(s)
Cloaca/virology , Ducks/virology , Influenza A virus/genetics , Influenza in Birds/epidemiology , Oropharynx/virology , Animal Migration , Animals , Charadriiformes/virology , Influenza A virus/classification , Influenza A virus/isolation & purification , Influenza in Birds/virology , Mexico/epidemiology , Prevalence , Reverse Transcriptase Polymerase Chain Reaction
15.
Rev Med Chil ; 134(4): 447-55, 2006 Apr.
Article in Spanish | MEDLINE | ID: mdl-16758080

ABSTRACT

BACKGROUND: Demands on primary health care services in Chile are increasing. The staff perception of specific sources of tension at work is not known. This knowledge is necessary to avoid preventable health problems caused by distress. AIM: To identify specific work stressors in primary health care facilities and to examine individual characteristics that could mediate their effects on health. MATERIAL AND METHODS: We evaluated organizational stressors (Perceived Work Characteristics for Health Services Survey), personal characteristics (Work Locus of Control Scale, Ways of Coping Check List) and distress (Goldberg General Health Questionnaire, Cooper Stress Symptoms Checklist) in a representative sample of 129 workers of 5 public Primary Health Care Centers of a borough in Santiago. RESULTS: Women and non-professional personnel reported more psychological and physical stress symptoms. Regression analysis showed that work stressors significantly explained the variance of psychological (26%) and physical (28%) distress symptoms. Perception of more role conflicts, less support of peers and superiors and less workload were predictors significantly associated with higher stress outcomes. Avoidance coping strategies were associated with more distress and mediated the effect of organizational stressors on health. CONCLUSIONS: We identified the groups at risk of stress in Primary Health Care Centers and specific sources of tension in the organization, as well as individual risk factors. Both should be addressed in interventions to reduce distress and prevent consequences on health.


Subject(s)
Adaptation, Psychological , Health Personnel/psychology , Occupational Diseases/diagnosis , Primary Health Care , Stress, Psychological/diagnosis , Female , Humans , Male , Occupational Diseases/psychology , Psychiatric Status Rating Scales , Sex Factors , Surveys and Questionnaires , Work Schedule Tolerance/psychology , Workload/psychology
16.
Rev. méd. Chile ; 134(4): 447-455, abr. 2006. ilus, tab
Article in Spanish | LILACS | ID: lil-428544

ABSTRACT

Background: Demands on primary health care services in Chile are increasing. The staff perception of specific sources of tension at work is not known. This knowledge is necessary to avoid preventable health problems caused by distress. Aim: To identify specific work stressors in primary health care facilities and to examine individual characteristics that could mediate their effects on health. Material and Methods: We evaluated organizational stressors (Perceived Work Characteristics for Health Services Survey), personal characteristics (Work Locus of Control Scale, Ways of Coping Check List) and distress (Goldberg General Health Questionnaire, Cooper Stress Symptoms Checklist) in a representative sample of 129 workers of 5 public Primary Health Care Centers of a borough in Santiago. Results: Women and non-professional personnel reported more psychological and physical stress symptoms. Regression analysis showed that work stressors significantly explained the variance of psychological (26%) and physical (28%) distress symptoms. Perception of more role conflicts, less support of peers and superiors and less workload were predictors significantly associated with higher stress outcomes. Avoidance coping strategies were associated with more distress and mediated the effect of organizational stressors on health. Conclusions: We identified the groups at risk of stress in Primary Health Care Centers and specific sources of tension in the organization, as well as individual risk factors. Both should be addressed in interventions to reduce distress and prevent consequences on health.


Subject(s)
Female , Humans , Male , Adaptation, Psychological , Health Personnel/psychology , Occupational Diseases/diagnosis , Primary Health Care , Stress, Psychological/diagnosis , Occupational Diseases/psychology , Psychiatric Status Rating Scales , Surveys and Questionnaires , Sex Factors , Work Schedule Tolerance/psychology , Workload/psychology
17.
Rev. chil. cir ; 58(2): 133-137, abr. 2006. tab, graf
Article in Spanish | LILACS | ID: lil-429202

ABSTRACT

No hemos encontrado en Chile publicaciones sobre la prevalencia de las herniorrafias inguinales y el objeto de esta presentación es dar a conocer estas tasas así como un estudio sobre la frecuencia de las hernias inguinales y su distribución por edad y sexo en el Servicio de Salud Metropolitano Oriente (SSMO) de Santiago. El estudio a nivel nacional se efectuó en los egresados del año 2002 utilizando las bases de datos del Instituto Nacional de Estadísticas, y del Ministerio de Salud. El estudio desarrollado en el SSMO, se llevó a cabo empleando los archivos del Departamento de Bioestadística del SSMO y las bases de datos elaboradas en el Servicio de Cirugía del Hospital Salvador y en la Unidad de Cirugía del CRS Cordillera Oriente de Santiago. La prevalencia de las herniorrafias inguinales en Chile fue 138,2/100.000 habitantes; esta cifra fue de 139,3 para los pacientes adscritos al Sistema Público de Salud, de 121 para los adscritos a las ISAPRES y de 119,5 para los asegurados en la (CAPREDENA). Dentro de la Región Metropolitana, la tasa del Servicio de Salud Metropolitano Oriente (SSMO) fue, con 217, superior a los restantes Servicios de Salud Metropolitanos que mostraron una tasa promedio de 110,8/100.000 habitantes. Estas tasas dan cuenta de una mala accesibilidad al tratamiento. El estudio efectuado en el SSMO mostró que las herniorrafias inguinales fueron el 59,3 por ciento del total. Esta proporción fue de 87,2 por ciento en la población infantil y de un 56,4 por ciento en los adultos. La relación varón/mujer general fue de 2,7/1 para las herniorrafias inguinales, siendo 4/1 para los adultos y 1,7/1 para los menores de 15 años. Estas cifras son muy inferiores a la dada a conocer en la literatura. Las herniorrafias inguinales se observaron con una frecuencia 13 veces mayor en el primer año de vida que en los años siguientes.


Subject(s)
Male , Adolescent , Adult , Humans , Female , Infant , Child, Preschool , Child , Middle Aged , Hernia, Inguinal/surgery , Hernia, Inguinal/epidemiology , Age Distribution , Chile/epidemiology , Prevalence , Sex Distribution
18.
Rev. chil. neuro-psiquiatr ; 44(1): 9-14, mar. 2006. ilus, tab
Article in Spanish | LILACS | ID: lil-476925

ABSTRACT

Las Disquinesias tardías son reacciones adversas frecuentes e invalidantes de aquellos fármacos relacionados con la transmisión dopaminérgica. Una proporción importante de pacientes que la padecen no responden a las terapias actualmente vigentes. En este estudio se randomizó a 28 pacientes portadores de Disquinesias tardías severas y refractarias a tratamiento habitual, provenientes del Instituto Psiquiátrico de Santiago, en dos grupos que recibieron Piridoxina (500 mg al día) o placebo por 4 semanas, siguiendo un periodo de lavado de 7 días tras los cuales ambos grupos se cruzaron, manteniendo tratamiento por 4 semanas adicionales. Se utilizó la escala AIMS (Abnormal Involuntary Movement Scale) para evaluar a cada paciente en la semana 2 y 4 de cada etapa del estudio. La Piridoxina fue bien tolerada y no hubo efectos adversos en el periodo de estudio, no encontrándose diferencias significativas en la mejoría de Disquinesias Tardía entre los grupos que recibieron Piridoxina o Placebo.


Tardive Dyskinesia is a common and disabling adverse effect of drugs acting on Dopaminergic pathways. An important proportion of patients does not respond to the conventional treatment. In this study 28 severe and refractory patients from a Psychiatric Hospital were randomized in a cross over design to placebo and high doses (500 mg per day) of Pyridoxine for 4 weeks each one. The patients were evaluated using the Abnormal Involuntary Movement Scale (AIMS) at 2 and 4 weeks of each cycle. Pyridoxine was well tolerated, and no adverse effect occurred during the study. No statistical differences between Pyridoxine and Placebo were found. Surprisingly, in both groups equally good responses were found.


Subject(s)
Humans , Male , Female , Dopamine Antagonists/adverse effects , Dyskinesia, Drug-Induced/drug therapy , Pyridoxine/pharmacology , Analysis of Variance , Double-Blind Method , Risk Factors
19.
J Ethnopharmacol ; 96(3): 389-401, 2005 Jan 15.
Article in English | MEDLINE | ID: mdl-15619557

ABSTRACT

Ethnomedical uses of 108 medicinal plant species, belonging to 52 families, 89 genera, used by the Teribe Amerindians of Bocas del Toro Province in Panama, along with their socio-cultural practices are reported here. The methods of administration of the herbal remedies, the plant parts used, their families and local names are also documented. The recorded medicinal plants were used mainly for fever, various type of pain and inflammation. The potential value of 26 plants and their traditional uses was elucidated through literature search.


Subject(s)
Indians, Central American , Medicine, Traditional , Phytotherapy/methods , Ethnobotany , Humans , Panama , Plants, Medicinal
20.
Enferm. Infecc. microbiol ; 17(6): 156-9, nov.-dic. 1997. tab
Article in Spanish | LILACS | ID: lil-210867

ABSTRACT

El presente trabajo describe retrospectivamente las características clínicas y la evolución de 24 pacientes con VIH/SIDA que requirieron manejo en la Unidad de Terapia Intensiva (UTI) del Hospital Angeles del Pedregal durante su hospitalización. En cinco pacientes (21 por ciento) el diagnóstico de infección por VIH se realizó al momento de su ingreso a la UTI. La causa más frecuente de ingreso a la UTI fue insuficiencia respiratoria que requirió ventilación mecánica en 81 por ciento de los casos. La mortalidad relacionada con el accidente que provocó ingreso a la UTI fue cercana a 80 por ciento. Sin embargo, en aquellos pacientes en los que la causa del ingreso a terapia intensiva fue una neumonía por P. carinii, la mortalidad fue de 55 por ciento. En conclusión, el uso de unidades de cuidados intensivos en el manejo de pacientes con VIH/SIDA puede ser de utilidad en algunos pacientes con SIDA que tienen insuficiencia respiratoria, particularmente cuando ésta es debida a neumonía por P. carinii. Sin embargo, en otras situaciones la utilidad del manejo en la UTI no es tan clara. Con frecuencia el diagnóstico de infección por VIH se realizó por vez primera en la UTI, pero en aquellos pacientes en los que ya se conoce su infección por VIH es indispensable que el médico tratante discuta con el paciente acerca de sus deseos de ingresar o no a una unidad de terapia intensiva durante el curso de su padecimiento, con el fin de evitar intervenciones no deseadas en aquellos pacientes que así lo indiquen


Subject(s)
Humans , Male , Female , Adult , Hospitalization , Intensive Care Units , Pneumonia, Pneumocystis/etiology , Pneumonia, Pneumocystis/therapy , Respiratory Insufficiency/etiology , Respiratory Insufficiency/therapy , Acquired Immunodeficiency Syndrome/complications , Acquired Immunodeficiency Syndrome/therapy
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