ABSTRACT
Krukenberg tumor is a malignancy in the ovary from a primary lesion in the gastrointestinal tract and a metastatic signet ring cell adenocarcinoma to the ovary. Stomach is the most common primary site, but other organs can serve as a primary site. The lymphatic system is the most likely route for metastasis. CA 125 levels can be used for screening for early detection of ovarian metastasis as well as for monitoring the course of disease. The prognosis of Krukenberg tumor is poor and no curative treatment is currently available.
Subject(s)
Carcinoma, Signet Ring Cell/secondary , Cough/etiology , Dyspnea/etiology , Krukenberg Tumor/secondary , Lung Neoplasms/secondary , Ovarian Neoplasms/diagnosis , Pneumonia/diagnosis , Stomach Neoplasms/pathology , Biomarkers, Tumor/analysis , Carcinoma, Signet Ring Cell/diagnosis , Carcinoma, Signet Ring Cell/pathology , Diagnosis, Differential , Fatigue/etiology , Female , Humans , Krukenberg Tumor/complications , Krukenberg Tumor/diagnosis , Krukenberg Tumor/diagnostic imaging , Lung Neoplasms/complications , Lung Neoplasms/diagnosis , Lung Neoplasms/diagnostic imaging , Lymphatic Metastasis , Middle Aged , Ovarian Neoplasms/diagnostic imaging , Pleural Effusion, Malignant/etiology , Positron-Emission Tomography , Stomach Neoplasms/diagnostic imaging , Tomography, X-Ray ComputedABSTRACT
A complex conglomerate of symptoms, signs, and abnormalities are present with POEMS syndrome, making the diagnosis, management and follow-up a challenge. Recognizing the disease early on may be difficult. Many patients are initially misdiagnosed as having others disorders, for example: multiple myeloma. There is no standard treatment for patients diagnosed with POEMS syndrome.
