ABSTRACT
Objective: From the onset of COVID-19 pandemic, the presence of previous cardiopathy was thought to be related with a worse prognosis of the disease. We aimed to analyse that theoretical adverse impact in a large cohort of patients. Method: We selected 1065 patients admitted for SARS-CoV-2 pneumonia between March and June 2020, divided in three groups according to (1) absence of cardiopathy, (2) presence of valvular heart disease or ischemic heart disease, or (3) presence of heart failure. We analysed the differences between groups regarding the need for admission in intensive care unit for mechanical ventilation or mortality during admission, or mortality during admission or in the next 6 months. Results: The factors that were associated with a worse prognosis both in acute phase and in the next 6 months were age, male gender, obesity and oncologic disease. The presence of previous cardiopathy did not have an adverse prognostic impact neither initially nor in the short term, in our study. Conclusions: We did not obtain significative association of the presence of cardiopathy with a worse medical evolution, neither in acute phase nor in the short term, of patients admitted for SARS-CoV-2 pneumonia.
Objetivo: Desde el inicio de la pandemia por enfermedad por coronavirus 2019 (COVID-19) se relacionó la presencia de cardiopatía previa con un peor pronóstico de la enfermedad. Nuestro objetivo fue analizar esa posible repercusión desfavorable en una cohorte amplia de pacientes. Método: Se incluyeron 1,065 pacientes ingresados con neumonía por coronavirus 2 del síndrome respiratorio agudo grave (SARS-CoV-2) entre marzo y junio de 2020, divididos en tres grupos, según no tuvieran cardiopatía previa (grupo 1), presentaran cardiopatía valvular o isquémica (grupo 2) o tuvieran insuficiencia cardiaca (grupo 3). Se analizaron las diferencias entre los grupos en cuanto a necesidad de ingreso en unidad de cuidados intensivos para ventilación mecánica o mortalidad durante el ingreso, o mortalidad durante el ingreso o a los seis meses. Resultados: Los factores que se asociaron con un peor pronóstico inicial y a los seis meses fueron la edad, el sexo masculino, la obesidad y la presencia de patología oncológica, sin que la presencia de cardiopatía supusiera una influencia pronóstica negativa inicial ni a corto plazo en nuestro trabajo. Conclusiones: No obtuvimos asociación significativa de la presencia de cardiopatía por si sola con una peor evolución en fase aguda ni a corto plazo de pacientes ingresados con neumonía por SARS-CoV-2.
Subject(s)
Atrial Appendage/surgery , Bacteremia/diagnosis , Postoperative Complications/diagnosis , Prostheses and Implants/microbiology , Staphylococcal Infections/diagnosis , Aged , Anti-Bacterial Agents/therapeutic use , Bacteremia/drug therapy , Echocardiography, Transesophageal/methods , Female , Humans , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Positron Emission Tomography Computed Tomography/methods , Postoperative Complications/drug therapy , Postoperative Complications/microbiology , Staphylococcal Infections/drug therapy , Treatment OutcomeABSTRACT
No disponible
Subject(s)
Humans , Male , Aged , Chondrosarcoma/diagnostic imaging , Pericardial Effusion/complications , Pericardial Effusion/diagnostic imaging , Mitral Valve Prolapse/complications , Prognosis , Mitral Valve Insufficiency/complications , Mitral Valve Insufficiency/diagnostic imaging , Tomography, Emission-Computed/methodsSubject(s)
Humans , Female , Aged , Calcinosis/diagnostic imaging , Atrial Appendage , Heart Diseases/diagnostic imagingSubject(s)
Atrial Appendage , Calcinosis , Heart Diseases , Aged , Calcinosis/diagnostic imaging , Female , Heart Diseases/diagnostic imaging , HumansABSTRACT
No disponible
Subject(s)
Humans , Coronary Vessels/diagnostic imaging , Coronary Vessels/pathology , Electrocardiography/methods , ST Elevation Myocardial Infarction/complications , ST Elevation Myocardial Infarction/diagnostic imaging , Coronary Occlusion/complications , Coronary Occlusion/diagnostic imagingABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Electrocardiography , Coronary Occlusion/diagnosis , Arterial Occlusive Diseases/diagnosisABSTRACT
No disponible
Subject(s)
Humans , Female , Aged, 80 and over , Myxoma/diagnosis , Cardiomegaly/diagnosis , Vascular Calcification/diagnosis , Ultrasonography/methodsABSTRACT
No disponible
Subject(s)
Humans , Female , Flecainide/adverse effects , Electrocardiography , Tachycardia/chemically inducedABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Tachycardia, Supraventricular/diagnosis , Tachycardia, Ventricular/diagnosis , Atrial Fibrillation/etiology , ElectrocardiographyABSTRACT
BACKGROUND: Coronary arterial disease is the main cause of morbidity in western countries and coronary angiography is the most important diagnosis test. Lately, coronary angiotomography has been introduced for studying coronary arteries in a non-invasive way. Our goal was to assess the diagnostic accuracy of coronary angiotomography in the diagnosis of coronary arterial disease. MATERIAL AND METHODS: Cross-sectional study for assessing diagnostic test comparing coronary angiotomography to invasive angiography in patients without previous coronary disease. All the patients underwent both tests consecutively in a blind way. Coronary arteries were studied according to the modified reference model of coronary segmentary analysis of the American Heart Association. Tomography validity indexes (sensitivity, specificity, positive--PPV--and negative--NPV--predictive values and global value) by patient, artery, and segment were calculated. RESULTS: We studied 121 patients (47 females--38.8%--and 74 males--61.2%-). Prevalence of coronary arterial disease was 38%. The most frequent risk factor detected was hypertension. We obtained a 100% sensitivity and NPV studying patients as a whole by patient, a specificity of 92% (95% CI: 86.0-99.0) and a global value of 94% (95% CI: 89.0-99.0). The higher validity by artery was for anterior descending artery with a specificity of 98% (CI95%: 90.0-96.0) and NPV of 97% (IC95%: 96.0-100). The segment with higher validity was distal right coronary artery with 100% specificity and PPV. CONCLUSION: A high diagnostic validity of coronary angiotomography was obtained and it could be considered as another diagnostic test for studying coronary arterial disease.
