ABSTRACT
No disponible
Subject(s)
Adult , Humans , Hospitals, General/statistics & numerical data , Tuberculosis, Pulmonary/epidemiology , Prevalence , Spain/epidemiology , Catchment Area, HealthABSTRACT
We present a case of bacteremic pneumonia caused by Nocardia otitidiscaviarum in a corticodependent COPD. Blood and sputum cultures on Mycobacterial media were positives and identification was done using 16S rDNA sequencing. In this article we review the most relevant communications about Nocardia spp infection and study the strain susceptibility using E-test.
Subject(s)
Bacteremia/complications , Immunocompromised Host , Nocardia Infections/complications , Nocardia , Pneumonia, Bacterial/complications , Pulmonary Disease, Chronic Obstructive/complications , Aged , Fatal Outcome , Humans , Male , Nocardia/isolation & purification , Nocardia Infections/diagnosis , Pulmonary Disease, Chronic Obstructive/immunologyABSTRACT
Presentamos un caso de neumonía bacteremica causada por Nocardiaotitidis caviarum en un paciente con bronconeumopatia crónica obstructiva corticodependiente. Los cultivos de sangre y esputo en medios para micobacterias resultaron positivos y la identificación se realizó mediante la secuenciación de 16S rDNA. En el presente artículo se realiza una revisión de conjunto sobre el agente etiológico y se practica el estudio de susceptibilidad de la cepa mediante la técnica de E-Test
We present a case of bacteremic pneumonia caused by Nocardia otitidiscaviarum in a corticodependent COPD. Blood and sputum cultures on Mycobacterial media were positives and identification was done using 16S rDNA sequencing. In this article we review the most relevant comunications about Nocardia spp infection and study the strain susceptibility using E-test
Subject(s)
Aged , Humans , Bacteremia/complications , Immunocompromised Host , Nocardia/isolation & purification , Nocardia Infections/complications , Pneumonia, Bacterial/complications , Pulmonary Disease, Chronic Obstructive/complications , Fatal Outcome , Nocardia Infections/diagnosis , Pulmonary Disease, Chronic Obstructive/immunologyABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Adult , Travel , Spain , South America , Retrospective Studies , Morbidity , Incidence , Hospitals, Urban , Emigration and Immigration , Africa , MalariaSubject(s)
AIDS-Related Opportunistic Infections/microbiology , HIV Infections/microbiology , HIV-1/growth & development , Pericarditis/microbiology , Salmonella Infections/virology , Salmonella/growth & development , Adult , Anti-Bacterial Agents/therapeutic use , HIV Infections/virology , Humans , Male , Ofloxacin/therapeutic use , Pericarditis/virology , Salmonella Infections/microbiology , Sepsis/microbiology , Sepsis/virologySubject(s)
Endocarditis, Bacterial/microbiology , Gram-Negative Bacterial Infections/microbiology , Stenotrophomonas maltophilia/isolation & purification , Aortic Valve Insufficiency/complications , Disease Susceptibility , Drug Resistance, Multiple, Bacterial , Drug Therapy, Combination/therapeutic use , Endocarditis, Bacterial/etiology , Gram-Negative Bacterial Infections/diagnosis , HIV Infections/complications , Humans , Male , Middle Aged , Mitral Valve Insufficiency/complications , Mouth/microbiology , Ofloxacin/therapeutic use , Rheumatic Heart Disease/complications , Risk Factors , Substance Abuse, Intravenous , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic useABSTRACT
No disponible
Subject(s)
Middle Aged , Male , Humans , Risk Factors , HIV Infections , Trimethoprim, Sulfamethoxazole Drug Combination , Substance Abuse, Intravenous , Ofloxacin , Mitral Valve Insufficiency , Mouth , Rheumatic Heart Disease , Drug Resistance, Multiple, Bacterial , Stenotrophomonas maltophilia , Aortic Valve Insufficiency , Disease Susceptibility , Endocarditis, Bacterial , Drug Therapy, Combination , Gram-Negative Bacterial InfectionsSubject(s)
Chickenpox/complications , Pneumonia, Viral/etiology , AIDS-Related Opportunistic Infections/diagnosis , AIDS-Related Opportunistic Infections/drug therapy , Acyclovir/therapeutic use , Adult , Antiviral Agents/therapeutic use , Chickenpox/drug therapy , Chickenpox/epidemiology , Child , Female , HIV Seropositivity/complications , Humans , Male , Pneumonia, Viral/drug therapy , Pneumonia, Viral/epidemiology , Risk Factors , Seasons , Smoking/adverse effectsABSTRACT
OBJECTIVES: Ten patients with AIDS and voiding disorders were assessed to determine the most common type of lower urinary tract dysfunction and its possible usefulness in detecting neurological disease. METHODS: A complete urodynamic evaluation was performed. RESULTS: The most common symptom was urge incontinence and the most common urodynamic finding was detrusor-external sphincter dyssynergia. Of the 5 patients found to have a neurological disorder, only 3 had demonstrable functional disorder of the lower urinary tract (2 patients had detrusor hyperreflexia: one of them had a history of encephalopathy from HIV and the other patient had polyneuritis; the third patient had myelitis and a urodynamically diagnosed sympathetic decentration. CONCLUSIONS: Knowing the functional disorders of patients with AIDS can avoid complications and improve patient quality of life. Furthermore, it can be useful in detecting an existing neurological lesion or one that may develop in the future.
Subject(s)
Acquired Immunodeficiency Syndrome/physiopathology , HIV-1 , Urethra/physiopathology , Urinary Bladder/physiopathology , Acquired Immunodeficiency Syndrome/complications , Adult , Chronic Disease , Female , Humans , Male , Middle Aged , Prospective Studies , Urination Disorders/etiology , Urination Disorders/physiopathology , UrodynamicsABSTRACT
The aim of the present study is to evaluate the relationship between the alpha tumor necrosis factor (TNF-alpha), interleukin 1 beta (IL-1 beta) and the neurological disease associated to the HIV-1 infection and different neurological manifestations (15 infections of the CNS and 11 AIDS-dementia complexes) and 14 from a control group. The mean value of TNF-alpha in CSF of patients with HIV-1 infection and AIDS-dementia complex was 19.8 +/- 30.6 pg/ml, superior to that of the control group (p < 0.05). The group of patients with HIV-1 and opportunistic CNS infection has a TNF-alpha value of 28.5 +/- 37.8 pg/ml, that is superior to that of the patients with the AIDS-dementia complex (TNF-alpha = 7.9 +/- 9.4 pg ml; p < 0.05). Within the group of patients with a CNS infection, the value of TNF-alpha was greater in those in the acute phase (44.2 +/- 42.4 pg/ml) than in those in the chronic phase (6.8 +/- 7.6 pg/ml; p < 0.05). The TNF-alpha in the CSF is a good marker of infection of the CNS in the HIV-1 infection.
Subject(s)
AIDS Dementia Complex/cerebrospinal fluid , Acquired Immunodeficiency Syndrome/diagnosis , Central Nervous System Diseases/diagnosis , Tumor Necrosis Factor-alpha/cerebrospinal fluid , AIDS Dementia Complex/diagnosis , Acquired Immunodeficiency Syndrome/cerebrospinal fluid , Acquired Immunodeficiency Syndrome/complications , Biomarkers , Central Nervous System Diseases/cerebrospinal fluid , Central Nervous System Diseases/etiology , Data Interpretation, Statistical , Enzyme-Linked Immunosorbent Assay , HIV-1 , Humans , Interleukin-1/bloodABSTRACT
BACKGROUND: The patients with human immunodeficiency virus (HIV) infection have hepatic abnormalities due to infective, neoplastic and toxic disorders. The aim of the present study was to describe the spectrum of liver disease in the HIV infection and to establish the usefulness and indications of hepatic biopsy. METHODS: The hepatic biopsies prospectively carried out in 50 patients infected by HIV with abnormal hepatic biochemical parameters, fever of unknown origin or space occupying lesions were evaluated. RESULTS: Hepatic granulomatosis was found in 37 patients (74%). In 15 (30%) the culture in Löwenstein medium was positive. The strains were typified as Mycobacterium tuberculosis in 14. This finding took place in 8 out of 18 biopsies carried out because of fever of unknown origin (FUO) (44%). The rate of granulomatosis due to mycobacteria was 40%. Other diagnoses were steatosis in 22 patients, chronic active hepatitis in 10, chronic lobular hepatitis in 3, infiltration by Hodgkin's lymphoma in one and metastatic invasion by non-differentiated carcinoma in one. Hepatic biopsy was diagnostic in 8 out of 18 carried out for FUO (44%) and in 24 out of 30 carried out for abnormal hepatic biochemical parameters (80%). CONCLUSIONS: In the evaluated patients with HIV infection, hepatic granulomatosis was the most common finding and was due to mycobacteria in 40%. Hepatic steatosis and chronic active and lobular hepatitis were the most common causes of abnormal hepatic biochemical parameters. Considering the high yield of hepatic biopsy, the authors think that it should be carried out in patients with HIV infection and FUO or unexplained abnormal hepatic biochemical parameters.
Subject(s)
HIV Infections/complications , Liver Diseases/etiology , Liver Diseases/pathology , Adult , Chronic Disease , Female , Fever of Unknown Origin/etiology , Hepatitis/etiology , Humans , Liver Diseases/microbiology , Male , Middle Aged , Mycobacterium Infections/etiology , Prospective StudiesABSTRACT
Herpes type infections in AIDS patients tend to be more severe, generalized and have a torpid evolution. We present here two cases of intravenous drug addicts with a clinical picture of ulcerative lesions with a scar in the perioral and ungual regions with an evolution of several months an which were diagnosed of Herpes Simplex by a histopathological study. They were treated with intravenous Acyclovir achieving a complete remission; one patient developed a pneumocystis carinii pneumonia a month later. We want to highlight the importance of this case as a clinical sign of profound cellular immunity depression as well as the risk of developing more severe conditions.
