ABSTRACT
PURPOSE: To report three cases of adenoviral keratoconjunctivitis in patients who have undergone photorefractive keratectomy and that just developed subepithelial infiltrates. METHODS: Description of patients that developed postoperative adenoviral keratoconjunctivitis after photorefractive keratectomy without influence in the final visual outcome. RESULTS: All patients presented adenoviral keratoconjunctivitis 2-3 months after refractive surgery. They developed multiple pinpoint subepithelial infiltrates in six eyes, without haze development. The final uncorrected visual acuity was better or equal to 20/30. CONCLUSION: Although patients undergoing photorefractive keratectomy might develop severe corneal scarring following ocular infections, such events may follow their natural evolution.
Subject(s)
Adenovirus Infections, Human/etiology , Eye Infections, Viral/etiology , Keratoconjunctivitis, Infectious/etiology , Photorefractive Keratectomy , Postoperative Complications/pathology , Adenovirus Infections, Human/pathology , Adult , Corneal Opacity/virology , Eye Infections, Viral/pathology , Humans , Keratoconjunctivitis, Infectious/pathology , Lasers, Excimer , MaleABSTRACT
Chloroperoxidase from Caldariomyces fumago was able to chlorinate 17 of 20 aromatic hydrocarbons assayed in the presence of hydrogen peroxide and chloride ions. Reaction rates varied from 0.6 min(-1) for naphthalene to 758 min(-1) for 9-methylanthracene. Mono-, di- and tri-chlorinated compounds were obtained from the chloroperoxidase-mediated reaction on aromatic compounds. Dichloroacenaphthene, trichloroacenaphthene, 9,10-dichloroanthracene, chloropyrene, dichloropyrene, dichlorobiphenylene and trichlorobiphenylene were identified by mass spectral analyses as products from acenaphthene, anthracene, pyrene and biophenylene respectively. Polycyclic aromatic hydrocarbons with 5 and 6 aromatic rings were also substrates for the chloroperoxidase reaction. The importance of the microbial chlorination of aromatic pollutants and its potential environmental impact are discussed.
Subject(s)
Chloride Peroxidase/metabolism , Fungi/enzymology , Hydrocarbons, Chlorinated/metabolism , Catalysis , Hydrocarbons, Chlorinated/chemistry , KineticsABSTRACT
Bilateral endogenous endophthalmitis is a rare condition initiated by infection by microbes in the bloodstream, such as those arising from a foci of infective endocarditis. We report a case and discuss the diagnostic aspects and the clinical outcome of a patient with characteristic findings of the disease. The patient was a 49 year old white male who had a metallic aortic valve implanted 7 months previously, and who presented to the hospital with 10 days of fever, cough and dyspnea, then diarrhea and mental confusion. On the second day of hospitalization, he experienced sudden loss of vision in both eyes. A Gram-positive coccobacillus was isolated from the bloodstream, he was treated with fluoroquinolone with disappearance of fever, decreased ocular inflammation, and improvement in his vision to light perception. He later underwent valve replacement surgery but died during the procedure. We review the occurrence of ocular signs and symptoms and their importance in patients with endocarditis.
Subject(s)
Endocarditis, Bacterial/complications , Endocarditis, Bacterial/microbiology , Endophthalmitis/etiology , Gram-Positive Bacteria/isolation & purification , Gram-Positive Bacterial Infections/complications , Gram-Positive Bacterial Infections/microbiology , Blood/microbiology , Culture Media , Endophthalmitis/microbiology , Fatal Outcome , Humans , Male , Middle AgedABSTRACT
A total of 336 couples from 10 villages of three Brazilian Indian tribes was studied in relation to 15 anthropometric characteristics. Correlation coefficients between husband and wife were generally positive, none of the negative ones reaching a probability level of 1% or less. Thirteen correlations attained this level, but none of the traits behaved similarly in the three tribes. Height adjustment taking into consideration the correlation between mates for age did not much alter the correlation coefficients, but a larger influence was observed after allowance for temporal effects. A significant pair of canonical variables was obtained considering sitting height and leg length, but factors related to facial and bone form, extracted through principal-components analysis, yielded correlations insignificantly different from zero.
Subject(s)
Anthropometry , Marriage , Body Height , Body Weight , Brazil , Facial Expression , Head/anatomy & histology , Indians, South AmericanABSTRACT
Forneceu-se informaçäo sobre os cariótipos de 552 indivíduos, que foi comparada com dados similares coletados previamente em 1.380 pessoas. Os resultados foram examinados de acordo com o tipo de averiquaçäo, e consideraram-se com mais detalhe os derivados de indicaçöes clínicas. Dois períodos de tempo foram comparados (1965-1979 e 1980-1985), e observaram-se algumas diferenças entre eles nas prevalências de anormalidades dos cromossomos sexuais, bem como de certos tipos de trissomia e rearranjos estruturais autossômicos. Foram descritas em detalhe quatro translocaçöes (1;3, 1;18, 9;11, 5;X) que podem ter condicionado problemas reprodutivos em seus portadores
Subject(s)
Humans , Male , Female , Genetic Counseling , Karyotyping , Sex Chromosome Aberrations/epidemiology , BrazilSubject(s)
Genetics, Population , Marriage , Military Personnel , Adolescent , Adult , Anthropometry , Brazil , Female , Humans , Male , Middle AgedABSTRACT
É feita uma revisäo de 662 casos encaminhados ao Departamento de Genética do Instituto de Biociências da Universidade Federal do Rio Grande do Sul e examinados entre novembro de 1978 e julho de 1982. Cerca de um terço deles foram enviados por pediatras, e um quarto por endocrinologistas. Os diagnósticos provisórios feitos por esses e outros médicos estavam corretos em 86% dos casos para síndrome de Down, mas em apenas 50% para outras doenças genéticas. Três tipos de pacientes ocorreram mais comumente: (a) Aqueles com aberraçöes cromossômicas (24); (b) Com cromossomos normais mas apresentando diversas malformaçöes (21%); e (c) Com doenças gênicas (12%). Uma nova análise dos indivíduos do grupo b indicou dois possíveis fatores etiológicos ambientais (paridade e nível socioeconômico baixo) e um genético (consangüinidade). Dois probandos deste grupo com pertubaçöes no desenvolvimento sexual que, com alta probabilidade, devem ser causadas por genes autossômicos recessivos, foram descritos em detalhe
Subject(s)
Humans , Chromosome Aberrations , Genetic Counseling , Down Syndrome/genetics , BrazilABSTRACT
Analysis of nine characteristics on 1,205 males and 932 females from 12 tribes or groups of tribes indicated a poor relationship between morphology and language, as well as moderate agreement with the variability expected considering geography only. Two samples in the Xingu area studied during an interval of half a century (1897-1947) showed remarkable similarity. The conformity of the Caingang morphology with those of other tribes and the distinctiveness of the Xavante and Tenetehara has been amply confirmed.
Subject(s)
Anthropometry , Indians, South American , Language , Brazil , Female , Humans , MaleABSTRACT
A alta frequencia de beta-talassemia em italianos e a participacao dos mesmos na formacao etnica do Rio Grande do Sul conduziram-nos a determinacao da frequencia desta condicao em uma amostra de 704 caucasoides da populacao de Porto Alegre. Empregando alguns criterios hematologicos para a triagem dos individuos e posterior estudo dos niveis de HbA2 e HbF das suas amostras sanguineas, obtivemos uma frequencia de 1,1% heterozigotos para a betatalassemia, sendo que 62% desses individuos eram de origem italiana e os demais descendentes de sirios, espanhois e libaneses
Subject(s)
Thalassemia , BrazilABSTRACT
Two cases of spontaneous epidural hematoma of the lumbar region are reported. Some considerations are drawn about the values of the early diagnosis before the incidence of neurological sequela. The clinical and radiological findings and the treatment of these hematomas are discussed. Lumbar puncture and myelography are the best method for the diagnosis. Treatment should be surgical, consisting of laminectomy with total excision of the hematoma.
Subject(s)
Hematoma, Epidural, Cranial/diagnosis , Spinal Diseases/diagnosis , Adult , Female , Humans , Male , Middle AgedABSTRACT
Measurements of height, face height, nose height, nose breadth, head length and head breadth from individuals living in 17 villages of six South American Indian tribes were compared using Mahalanobis's morphological distances and their partition into size and shape components. Total D2 values correlate well with estimates of linguistic differentiation, but not with geographic distances between tribes. Three of the six tribes were also studied for blood polymorphisms, and again measures of distances based on these haematological traits did not correlate well with the morphological ones. The shape component was about three times as important as size in contributing to the intertribal variation.