ABSTRACT
The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.
Subject(s)
Epstein-Barr Virus Infections/diagnosis , Gingivitis/virology , Kidney Transplantation , Papillomavirus Infections/diagnosis , Periodontitis/virology , Case-Control Studies , DNA, Viral/genetics , Gingivitis/diagnosis , Herpesvirus 4, Human/genetics , Herpesvirus 4, Human/isolation & purification , Humans , Papillomaviridae/genetics , Papillomaviridae/isolation & purification , Periodontitis/diagnosis , Polymerase Chain ReactionABSTRACT
Currently, genital tract infection by human papillomavirus (HPV) is the most prevalent sexually transmitted virosis in the world. However, there are stillgaps in knowledge regarding the etiology of penile cancer, and the pathogenic processes of HPV in men are not completely understood, especially in cases ofsubclinical infections. This study aimed to determine the prevalence of HPV infection in penile swab samples, derived from a clinically asymptomatic malepopulation. For this purpose, 261 samples were analysed, collected between 2010 and 2013 in different institutions of the city of Rio de Janeiro, includinghospitals , a laboratory of clinical analysis, and a metallurgical company...
Atualmente, a infecção do trato genital pelo papilomavírus humano (HPV) é uma das viroses sexualmente transmissíveis mais prevalentes do mundo. Entretanto, ainda existem lacunas de conhecimento a respeito da citologia do câncer de pênis, e os processos patogênicos do HPV no homem ainda não estão totalmente elucidados, principalmente nos casos de infecções subclínicas. Este estudo teve como objetivo determinar a prevalência da infecção por HPV em amostras de esfregaços de pênis, oriundos de uma população masculina clinicamente assintomática. Para tanto, foram analisadas 261 amostras, coletadas entre 2010 e 2013 em diferentes instituições na cidade do Rio de Janeiro, incluindo hospitais, um laboratório de análises clínicas e, uma empresa metalúrgica...
