1.
Chem Sci
; 7(5): 3154-3161, 2016 May 01.
Article
in English
| MEDLINE
| ID: mdl-29997807
ABSTRACT
We present an operationally simple approach to 2,2'-bipyridine macrocycles. Our method uses simple starting materials to produce these previously hard to access rotaxane precursors in remarkable yields (typically >65%) across a range of scales (0.1-5 mmol). All of the macrocycles reported are efficiently converted (>90%) to rotaxanes under AT-CuAAC conditions. With the requisite macrocycles finally available in sufficient quantities, we further demonstrate their long term utility through the first gram-scale synthesis of an AT-CuAAC [2]rotaxane and extend this powerful methodology to produce novel Sauvage-type molecular shuttles.
2.
Chem Sci
; 7(6): 3935, 2016 06 01.
Article
in English
| MEDLINE
| ID: mdl-30123466
ABSTRACT
[This corrects the article DOI: 10.1039/C6SC00011H.].