ABSTRACT
ELISA kits from different commercial firms were evaluated and compared with monoclonal immunosorbent agglutination test ISAGA for detection anti-T. gondii IgM antibody. The results presented in this study show that both ELISA-IgM tests, as well from Organon, as from Abbott firms promise to be of the same value for the diagnosis of acute acquired and congenital toxoplasmosis.
Subject(s)
Reagent Kits, Diagnostic , Toxoplasmosis, Congenital/diagnosis , Toxoplasmosis/diagnosis , Adult , Antibodies, Anti-Idiotypic/analysis , Antibodies, Monoclonal , Child , Enzyme-Linked Immunosorbent Assay , Female , Humans , Immunoglobulin M/immunology , Pregnancy , Pregnancy Complications, Infectious/diagnosisSubject(s)
Pregnancy Complications, Infectious/diagnosis , Toxoplasmosis, Congenital/diagnosis , Toxoplasmosis, Ocular/diagnosis , Toxoplasmosis/diagnosis , Adult , Animals , Antibodies, Protozoan/analysis , Child , Diagnostic Tests, Routine , False Negative Reactions , Female , Humans , Immunoglobulin G/analysis , Immunoglobulin M/analysis , Immunologic Tests , Infant, Newborn , Poland , Pregnancy , Pregnancy Complications, Infectious/immunology , Toxoplasma/immunology , Toxoplasmosis/immunology , Toxoplasmosis, Congenital/immunology , Toxoplasmosis, Ocular/immunologyABSTRACT
Both humoral and cellular immune response during experimental toxoplasmosis of rabbits were studied in different stages of pregnancy. The application of different schemes of immunization made possible to detect immunological phenomena in particular stage of development depending on foetus evolution. The research conducted so far, has demonstrated no significant protective influence of humoral as well as cellular resistance to foetus infection of mothers acute infection.
