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Article in German | MEDLINE | ID: mdl-61920

ABSTRACT

In rats of kind of Kruschinskij-Molodkina the number of cells in the stellate ganglion was diminished to 0.5% of the norm after eliminating the sympathetic tonus by means of guanethidine. These animals died of cardiac thrombosis during stress situations. This thrombosis cannot be explained by adrenalin, corticosteroids or thromboplastin spreading in the blood stream. A factor, the nature of which has still to be explained, may be assumed to be responsible for thrombosis to develop during stress situations in animals whose sympathetic tonus has been eliminated by guanethidine.


Subject(s)
Guanethidine/pharmacology , Sympathetic Nervous System/drug effects , Thrombosis/etiology , Adrenergic alpha-Antagonists , Adrenergic beta-Antagonists , Animals , Hearing Loss, Noise-Induced , Rats
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