ABSTRACT
Primary malignant tumours of the chest wall are among the rarest cartilaginous tumours. Chondrosarcomas present a difficult clinical problem due to its high resistance to conventional chemotherapy and radiotherapy. Complete surgical resection has been the cornerstone for treatment. It has been associated with better prognosis, survival and less recurrence in contrast to other methods of therapy. Patients with chondrosarcomas generally have a good prognosis when surgical resection is performed. Improvement in outcomes is seen when patients are evaluated in a multidisciplinary care facility. We present the case of a 66-year-old male patient that exhibits a chest wall mass diagnosed as a chondrosarcoma. After chemotherapy failure, our patient was successfully treated with complete surgical excision of the mass. Final tissue biopsy report was remarkable for a p53 gene mutation, which is known to be associated with tumour progression and loss of growth control.
ABSTRACT
We describe a case of an unusual fast growing lung micropapillary-predominant adenocarcinoma in a nonsmoker male patient without pre-existing lung disease. Adenocarcinomas have been described to be slow growing tumors, however our patient presented a fast-growing rate over a period of 21 days. When the patient failed broad spectrum antibiotic coverage, malignancy became part of the differential diagnosis. Once malignancy was detected, prompt identification and treatment was started in order to improve prognosis of the patients.
