ABSTRACT
Los pacientes con mieloma múltiple (MM) no tienen mayor incidencia de pancreatitis aguda ni diferente etiología de ésta que la población general. Sin embargo, pueden presentar pancreatitis aguda, o hiperamilasemia o hiperlipasemia aisladas, por causas que son poco habituales sin la presencia de la enfermedad hematológica. En los pacientes con MM, la afectación hepática aparece en el 30 al 50% de los casos. Fundamentalmente se produce como infiltración difusa de predominio sinusoidal, y la aparición en forma de nódulos es menos frecuente. Se presenta el caso de un paciente que recibió un trasplante de médula ósea por MM y que presentó un cuadro compatible clínica y analíticamente con pancreatitis aguda de etiología no filiada, durante el que se identificó la presencia de múltiples lesiones hepáticas ocupantes de espacio que se diagnosticaron mediante biopsia como recidiva extramedular de mieloma (AU)
Patients with multiple myeloma (MM) do not have a higher incidence of acute pancreatitis or pancreatitis of other etiologies than the general population. However, these patients may develop acute pancreatitis, or hyperamylasemia or isolated hyperlipasemia, due to etiologies that are highly infrequent in the absence of hematological disease. Liver involvement is found in 30 50% of patients with MM and mainly manifests as diffuse sinusoidal infiltration and less frequently in the form of nodules. We report the case of a patient who underwent bone marrow transplantation due to MM who showed clinical and laboratory findings compatible with acute pancreatitis of unknown origin, during which the presence of multiple space-occupying hepatic lesions was identified. Based on the results of biopsy, a diagnosis of extramedullary recurrence of MM was established (AU)
Subject(s)
Humans , Male , Adult , Bone Marrow Transplantation/adverse effects , Pancreatitis, Acute Necrotizing/diagnosis , Liver Neoplasms/pathology , Multiple Myeloma/surgery , RecurrenceABSTRACT
Patients with multiple myeloma (MM) do not have a higher incidence of acute pancreatitis or pancreatitis of other etiologies than the general population. However, these patients may develop acute pancreatitis, or hyperamylasemia or isolated hyperlipasemia, due to etiologies that are highly infrequent in the absence of hematological disease. Liver involvement is found in 30-50% of patients with MM and mainly manifests as diffuse sinusoidal infiltration and less frequently in the form of nodules. We report the case of a patient who underwent bone marrow transplantation due to MM who showed clinical and laboratory findings compatible with acute pancreatitis of unknown origin, during which the presence of multiple space-occupying hepatic lesions was identified. Based on the results of biopsy, a diagnosis of extramedullary recurrence of MM was established.
Subject(s)
Bone Marrow Transplantation , Liver Neoplasms/secondary , Multiple Myeloma/pathology , Multiple Myeloma/secondary , Pancreatitis/etiology , Postoperative Complications/diagnosis , Acute Disease , Adult , Amylases/blood , Humans , Lipase/blood , Liver Neoplasms/diagnostic imaging , Male , Multiple Myeloma/surgery , Pancreatitis/blood , Postoperative Complications/pathology , Tomography, X-Ray Computed , Transplantation, Autologous , UltrasonographyABSTRACT
Inflammatory cloacogenic polyps are infrequent lesions that usually arise in the anorectal zone. The most common clinical presentation is rectal bleeding. Two cases of rectal bleeding related to cloacogenic polyps with different endoscopic appearance are reported. Endoscopists should be familiar with this entity, which should be considered in the differential diagnosis with other polypoid lesions observed in colonoscopy.
Subject(s)
Intestinal Polyps/diagnosis , Rectal Diseases/diagnosis , Adult , Anal Canal , Colonoscopy , Diagnosis, Differential , Female , Gastrointestinal Hemorrhage/etiology , HumansABSTRACT
Los pólipos inflamatorios cloacogénicos son lesiones poco frecuentes, que suelen surgir en la zona anorrectal. La presentación clínica más frecuente es en forma de sangrado rectal. Se presentan 2 casos de pólipos cloacogénicos con distinto aspecto endoscópico y clínica de rectorragia. El endoscopista debe tener en cuenta la existencia de esta entidad y considerarla en el diagnóstico diferencial con otras lesiones polipoideas que se pueden observar en la colonoscopia
Inflammatory cloacogenic polyps are infrequent lesions that usually arise in the anorectal zone. The most common clinical presentation is rectal bleeding. Two cases of rectal bleeding related to cloacogenic polyps with different endoscopic appearance are reported. Endoscopists should be familiar with this entity, which should be considered in the differential diagnosis with other polypoid lesions observed in colonoscopy
