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Endocrinol Diabetes Nutr (Engl Ed)
; 69(8): 629-645, 2022 Oct.
Article
in English
| MEDLINE
| ID: mdl-36369235
ABSTRACT
The risk of suffering from gonadal germ cell tumors (GCT) is increased in some patients with different sexual development (DSD), mainly in those with Y chromosome material. This risk, however, varies considerably depending on a multitude of factors that make the decision for prophylactic gonadectomy extremely difficult. In order to make informed recommendations on the convenience of this procedure in cases where there is potential for malignancy, this consensus guide evaluates the latest clinical evidence, which is generally low, and updates the existing knowledge in this field.