ABSTRACT
The use of implants for oral rehabilitation of edentulous spaces has recently been on the increase, which has also led to an increase in complications such as peri-implant inflammation or peri-implantitis. Chronic inflammation is a risk factor for developing oral squamous cell carcinoma (OSCC).Objectives: To review the literature of cases that associate implant placement with the development of oral cancer. Study design: We present two clinical cases and a systematic review of literature published on the relationship between oral cancer and implants. Results: We found 13 articles published between the years 1996 and 2009, referencing 18 cases in which the osseointegrated implants are associated with oral squamous cell carcinoma. Of those, 6 articles were excluded because they did not meet the inclusion criteria. Of the 18 cases reported, only 7 cases did not present a previous history of oral cancer or cancer in other parts of the body. Conclusions: Based on the review of these cases, a clear cause-effect relationship cannot be established, although it can be deduced that there is a possibility that implant treatment may constitute an irritant and/or inflammatory cofactor which contributes to the formation and/or development of OSCC (AU)
Subject(s)
Humans , Mouth Neoplasms/epidemiology , Dental Implants/adverse effects , Neoplasms, Squamous Cell/epidemiology , Inflammation/physiopathology , Risk FactorsABSTRACT
UNLABELLED: The use of implants for oral rehabilitation of edentulous spaces has recently been on the increase, which has also led to an increase in complications such as peri-implant inflammation or peri-implantitis. Chronic inflammation is a risk factor for developing oral squamous cell carcinoma (OSCC). OBJECTIVES: To review the literature of cases that associate implant placement with the development of oral cancer. STUDY DESIGN: We present two clinical cases and a systematic review of literature published on the relationship between oral cancer and implants. RESULTS: We found 13 articles published between the years 1996 and 2009, referencing 18 cases in which the osseointegrated implants are associated with oral squamous cell carcinoma. Of those, 6 articles were excluded because they did not meet the inclusion criteria. Of the 18 cases reported, only 7 cases did not present a previous history of oral cancer or cancer in other parts of the body. CONCLUSIONS: Based on the review of these cases, a clear cause-effect relationship cannot be established, although it can be deduced that there is a possibility that implant treatment may constitute an irritant and/or inflammatory cofactor which contributes to the formation and/or development of OSCC.
Subject(s)
Carcinoma, Squamous Cell/etiology , Dental Implants/adverse effects , Mouth Neoplasms/etiology , Adult , Aged , Humans , MaleABSTRACT
PURPOSE: To identify the risk of complications (eg, implant loss, infection, peri-implantitis, and mucositis) in a group of patients treated with osseointegrated implants and to assess the effect of smoking on this risk. MATERIALS AND METHODS: A retrospective cohort study of patients treated in the Unit of Implantology, University of Barcelona Faculty of Dentistry was performed. All patients had already undergone prosthetic treatment, and the minimal follow-up time after implant surgery was 6 months. RESULTS: A total of 295 patients fulfilled the inclusion criteria; 56.9% were women and 43.1% were men. They received a total of 1,033 implants. There were 209 complications (32 cases of implant loss, 2 cases of infection, 70 cases of peri-implantitis, and 105 cases of mucositis). The smoking habit was associated with an increased risk of complications (P = .008). CONCLUSION: Smokers had an increased risk of complications, including infection, implant loss, mucositis, and peri-implantitis, compared with nonsmoking patients.