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1.
Arch Soc Esp Oftalmol (Engl Ed) ; 97(7): 409-412, 2022 Jul.
Article in English | MEDLINE | ID: mdl-35779897

ABSTRACT

Intravascular papillary endothelial hyperplasia (IPEH) is characterized by proliferation of endothelial cells usually occurring within a long-standing vascular malformation or tumor. IPEH usually affects neck, head and lower extremities, and few orbital and eyelid cases have been reported. We present a unique case, a 48-years-old man with a purple, elevated, multilobular conjunctival lesion of three-weeks duration that underwent an excisional biopsy. Pathological features revealed intravascular papillary endothelial hyperplasia (Masson's tumor).


Subject(s)
Vascular Neoplasms , Conjunctiva/pathology , Endothelial Cells/pathology , Eyelids/pathology , Humans , Hyperplasia/pathology , Male , Middle Aged , Vascular Neoplasms/pathology
2.
Arch. Soc. Esp. Oftalmol ; 97(7): 409-412, jul. 2022. ilus, tab
Article in Spanish | IBECS | ID: ibc-209074

ABSTRACT

La hiperplasia endotelial papilar intravascular (IPEH) se caracteriza por la proliferación de células endoteliales generalmente producida dentro de una malformación vascular previa o un tumor. La IPEH suele afectar cuello, cabeza y extremidades inferiores, se han publicado pocos casos en la órbita ocular y párpados. Presentamos un caso único, un hombre de 48 años con una lesión conjuntival púrpura, elevada y multilobular de tres semanas de duración que se sometió a una biopsia excisional. Las características patológicas revelaron una hiperplasia endotelial papilar intravascular (tumor de Masson) (AU)


Intravascular papillary endothelial hyperplasia (IPEH) is characterized by proliferation of endothelial cells usually occurring within a long-standing vascular malformation or tumor. IPEH usually affects neck, head and lower extremities, and few orbital and eyelid cases have been reported. We present a unique case, a 48-year-old man with a purple, elevated, multilobular conjunctival lesion of three-weeks duration that underwent an excisional biopsy. Pathological features revealed intravascular papillary endothelial hyperplasia (Masson's tumor) (AU)


Subject(s)
Humans , Male , Middle Aged , Vascular Neoplasms/pathology , Endothelial Cells/pathology , Conjunctiva/pathology , Hyperplasia/pathology
3.
Arch Soc Esp Oftalmol ; 91(3): 145-8, 2016 Mar.
Article in English, Spanish | MEDLINE | ID: mdl-26796428

ABSTRACT

CASE REPORT: A 17-year- old male with 2years history of an intraocular mass and progressive visual loss of the left eye. Spontaneous sclera rupture occurred during enucleation. Microscopic evaluation with H-E, PAS and immunohistochemistry (NSE, GAFP, SYN, CD99) revealed a small blue round cell malignant neoplasm with extensive necrosis and apoptosis. The optic nerve, ciliary body, choroid, anterior chamber, and sclera were infiltrated. SYN was positive and CD99 was negative in neoplastic cells, consistent with a poorly differentiated retinoblastoma. DISCUSSION: Retinoblastoma is the most frequent primary intraocular malignant tumour in childhood, but occasionally older patients can be affected. Immunohistochemistry is mandatory in poorly differentiated retinoblastomas.


Subject(s)
Retinal Neoplasms/diagnosis , Retinoblastoma/diagnosis , Adolescent , Eye Enucleation , Humans , Male , Optic Nerve , Orbit , Retinal Neoplasms/surgery , Retinoblastoma/surgery
4.
Arch Soc Esp Oftalmol ; 81(10): 611-3, 2006 Oct.
Article in Spanish | MEDLINE | ID: mdl-17075765

ABSTRACT

CLINICAL CASE: We report a case of a 46-year-old woman who developed a tender, painful mass in the left superior eyelid over a period of about 6 months. This was a frontal mucocele with atypical clinical and histopathologic features. DISCUSSION: Most mucoceles arise from the frontal or ethmoidal sinuses. Frontal mucoceles usually cause outward and downward displacement of the globe, and are often associated with fullness in the supero-nasal and medial canthal region and a palpable mass.


Subject(s)
Frontal Sinus , Mucocele/diagnosis , Paranasal Sinus Diseases/diagnosis , Female , Humans , Middle Aged
5.
Arch Soc Esp Oftalmol ; 81(6): 315-20, 2006 Jun.
Article in Spanish | MEDLINE | ID: mdl-16804774

ABSTRACT

OBJECTIVE: To assess the main clinical, genetic, histopathological and ultrastructural features of Mexican patients with macular corneal dystrophy, and to compare the results with those previously reported. METHOD: We analyzed six cases where a histopathologic diagnosis of macular corneal dystrophy had been made between 1957 and 2004. RESULTS: Clinically, all corneas showed focal grayish-white stromal opacities with diffuse edges. Histopathologically, intrastromal granules stained strongly positive with Alcian blue and colloidal iron. Transmission electron microscopy showed enlargement of smooth endoplasmic reticulum and the presence of intracytoplasmic vacuoles that corresponded to glycosaminoglycans. Genetic analysis showed novel mutations in the CHST6 gene in 2 of the patients. CONCLUSIONS: Females were more affected than males and the mean age at the time of diagnosis was older than that reported previously, however the clinical, histopathological and ultrastructural features were similar to those of previous reports. As described in other cases in the literature, in some instances a disorder is found in CHST6 gene as a basis for this condition.


Subject(s)
Corneal Dystrophies, Hereditary , Adult , Corneal Dystrophies, Hereditary/diagnosis , Corneal Dystrophies, Hereditary/enzymology , Corneal Dystrophies, Hereditary/genetics , Corneal Dystrophies, Hereditary/pathology , Corneal Dystrophies, Hereditary/ultrastructure , Corneal Stroma/pathology , Female , Humans , Male , Microscopy, Electron, Transmission , Mutation , Sex Factors , Sulfotransferases/genetics
6.
Arch Soc Esp Oftalmol ; 81(4): 217-9, 2006 Apr.
Article in Spanish | MEDLINE | ID: mdl-16688646

ABSTRACT

CASE REPORT: Pigmented conjunctival lesions are a diagnostic challenge for the clinician. A 37-year-old man presented with a pigmented mass involving the conjunctiva of his right eye. Clinically, a diagnosis of malignant melanoma was made and a wide excision of the tumor was performed. The histopathologic diagnosis was seborrheic keratosis. DISCUSSION: Seborrheic keratosis is a benign lesion which occurs on the eyelids and face of middle-aged and elderly individuals. The occurrence of this lesion on the conjunctiva is rare, however there are 2 cases reported in the world literature. Seborrheic keratosis should be considered in the differential diagnosis of conjunctival pigmented lesions.


Subject(s)
Conjunctival Diseases/pathology , Keratosis, Seborrheic/pathology , Adult , Conjunctiva/pathology , Conjunctiva/surgery , Conjunctival Diseases/surgery , Humans , Keratosis, Seborrheic/surgery , Male , Ophthalmologic Surgical Procedures
7.
Arch. Soc. Esp. Oftalmol ; 81(4): 217-220, abr. 2006. ilus
Article in Es | IBECS | ID: ibc-046748

ABSTRACT

Caso clínico: Las lesiones conjuntivales pigmentadasrepresentan un reto diagnóstico para el clínico.Hombre de 37 años de edad quien presentó unamasa conjuntival pigmentada en su ojo derecho.Clínicamente se diagnosticó como melanoma, porlo que se realizó escisión completa del tumor. Eldiagnóstico histopatológico fue de queratosis seborreica.Discusión: La queratosis seborreica es una lesiónbenigna que se presenta en los párpados y en la carade individuos de edad media y adultos mayores. Eldesarrollo de esta lesión en la conjuntiva es pocofrecuente, solo se han informado 2 casos en la literatura.La queratosis seborreica debe ser consideradaen el diagnóstico diferencial de lesiones conjuntivalespigmentadas


Case report: Pigmented conjunctival lesions are a ;;diagnostic challenge for the clinician. A 37-yearold ;;man presented with a pigmented mass involving ;;the conjunctiva of his right eye. Clinically, a diagnosis ;;of malignant melanoma was made and a wide ;;excision of the tumor was performed. The histopathologic ;;diagnosis was seborrheic keratosis. ;;Discussion: Seborrheic keratosis is a benign lesion ;;which occurs on the eyelids and face of middleaged ;;and elderly individuals. The occurrence of this ;;lesion on the conjunctiva is rare, however there are ;;2 cases reported in the world literature. Seborrheic ;;keratosis should be considered in the differential ;;diagnosis of conjunctival pigmented lesions


Subject(s)
Male , Adult , Humans , Keratosis, Seborrheic/surgery , Conjunctival Neoplasms/surgery , Diagnosis, Differential , Melanoma/diagnosis , Darier Disease/diagnosis
8.
Arch Soc Esp Oftalmol ; 79(11): 543-8, 2004 Nov.
Article in Spanish | MEDLINE | ID: mdl-15578283

ABSTRACT

PURPOSE: To analyze the clinicopathologic characteristics of uveal melanoma in Mexican patients under thirty years old. METHODS: We reviewed the cases from the Service of Ophthalmic Pathology with histopathologic diagnosis of uveal melanoma from 1957 to March 2002. The data analyzed were: age, gender, affected eye, clinical diagnosis, size, cellular type, mitotic index, lymphocytic infiltrate, vascular pattern, necrosis, vascular and/or intraocular invasion and orbital extension. RESULTS: We reviewed 122 cases diagnosed with uveal melanoma, and 14 patients were younger than 30 years old (11.4%). The mean age was 21.7 years, with female preponderance. Preoperative clinical diagnoses were uveal melanoma in 92.8%, most of the cases originated from choroid. The most frequent cellular type was spindle cells and 3 and 4 Folberg's vascular patterns. CONCLUSIONS: Our results suggest that the clinicians should consider uveal melanoma more frequently as another differential diagnosis in patients under thirty years with an intraocular tumor. The histological characteristics found have been correlated with a better prognosis.


Subject(s)
Melanoma/pathology , Uveal Neoplasms/pathology , Adolescent , Adult , Female , Humans , Male , Mexico
9.
Arch. Soc. Esp. Oftalmol ; 79(11): 543-548, nov. 2004. tab, ilus
Article in Spanish | IBECS | ID: ibc-81643

ABSTRACT

Objetivo: Determinar las características clínicopatológicas del melanoma uveal en pacientes mexicanos menores de treinta años. Métodos: Se revisaron los casos del Servicio de Patología Oftálmica con diagnóstico histopatológico de melanoma uveal de 1957 a marzo de 2002. Se analizaron: edad, sexo, ojo afectado, diagnóstico clínico, tamaño, tipo celular, índice mitótico, infiltrado linfocitario, patrón vascular, necrosis, invasión vascular y/o de estructuras intraoculares así como extensión orbitaria. Resultados: De 122 casos con diagnóstico de melanoma uveal, 14 correspondieron a pacientes menores de 30 años (11,4%). La edad promedio fue de 21,7 años, con predominio en mujeres. El diagnóstico clínico preoperatorio fue melanoma uveal en un 92,85 %, originándose en coroides en la mayoría de los casos. El tipo celular más frecuente fue el de células fusiformes, con predominio de los patrones vasculares 3 y 4 de Folberg. Conclusiones: Nuestros resultados sugieren que los clínicos deben considerar el melanoma uveal como un diagnóstico diferencial más en pacientes menores de 30 años con un tumor intraocular. Las características histológicas observadas se han correlacionado con un mejor pronóstico(AU)


Purpose: To analyze the clinicopathologic characteristics of uveal melanoma in Mexican patients under thirty years old. Methods: We reviewed the cases from the Service of Ophthalmic Pathology with histopathologic diagnosis of uveal melanoma from 1957 to March 2002. The data analyzed were: age, gender, affected eye, clinical diagnosis, size, cellular type, mitotic index, lymphocytic infiltrate, vascular pattern, necrosis, vascular and/or intraocular invasion and orbital extension. Results: We reviewed 122 cases diagnosed with uveal melanoma, and 14 patients were younger than 30 years old (11.4%). The mean age was 21.7 years, with female preponderance. Preoperative clinical diagnoses were uveal melanoma in 92.8%, most of the cases originated from choroid. The most frequent cellular type was spindle cells and 3 and 4 Folberg´s vascular patterns. Conclusions: Our results suggest that the clinicians should consider uveal melanoma more frequently as another differential diagnosis in patients under thirty years with an intraocular tumor. The histological characteristics found have been correlated with a better prognosis(AU)


Subject(s)
Humans , Male , Female , Adolescent , Adult , Melanoma/epidemiology , Uveal Neoplasms/epidemiology , Age and Sex Distribution , Choroid/pathology , Nevus, Spindle Cell/pathology
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