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Rev. esp. patol. torac ; 31(4): 232-239, dic. 2019. graf, tab
Article in Spanish | IBECS | ID: ibc-187183

ABSTRACT

Objetivo: a pesar del interés creciente en la asociación entre apnea de sueño (AS) y cáncer, apenas existen estudios que investiguen tumores concretos. Nuestro objetivo fue analizar la prevalencia y características clínicas de la AS en mujeres con cáncer de mama (CM). Métodos: estudio piloto transversal. Se incluyen consecutivamente 83 mujeres entre 18 - 65, años diagnosticadas por primera vez de CM. En todos los casos se realizó un cuestionario clínico y una poligrafía respiratoria domiciliaria. La AS se definió como un índice de apneas-hipopneas (IAH) ≥5, y el síndrome de apneas-hipopneas del sueño (SAHS) como la asociación de un IAH ≥5 y excesiva somnolencia diurna (ESD, Epworth >10). Resultados: la media (DE) de edad fue de 48,8 (8,8) años, el índice de masa corporal (IMC) de 27,4 (5,4) y el 50,6% eran postmenopáusicas. La prevalencia de AS fue del 51,8% (43 casos), y la mediana de IAH de 5,1 (RIQ 2 - 9,4). De las 43 pacientes con AS, 32 presentaron un IAH 5 - 14,9 y 11 IAH ≥15. La prevalencia de SAHS fue del 10,8% (9 casos). Comparadas con las mujeres sin AS, aquellas con AS presentaron más ronquido, pero no hubo diferencias en otros síntomas relacionados con el sueño. En el análisis multivariado, la edad y las variables antropométricas, pero no la ESD, se asociaron independientemente a la AS. Conclusión: la prevalencia de AS es elevada en mujeres de mediana edad diagnosticadas de CM, aunque la mayoría no presentan ESD ni otras características diferenciales. La edad y la obesidad fueron predictores de AS en esta población


Objective: Despite growing interest in the association between sleep apnea and cancer, there are hardly any studies that research specific tumors. Our objective was to analyze the prevalence and characteristics of sleep apnea in women with breast cancer. Methods: A transversal pilot study. 83 women between the ages of 18 and 65 diagnosed with breast cancer for the first time were included consecutively. All participants completed a clinical questionnaire and underwent home respiratory polygraphy. Sleep apnea was defined as an apnea-hypopnea index (AHI) ≥5 and sleep apnea-hypopnea syndrome (SAHS) was defined as the association between an AHI ≥5 and excessive daytime sleepiness (EDS, Epworth >10). Results: The average (SD) age was 48.8 (8.8) years old, the body mass index (BMI) was 27.4 (5.4) and 50.6% were postmenopausal. The prevalence of sleep apnea was 51.8% (43 cases) and the average AHI was 5.1 (IQR: 2 - 9.4). Of the 43 patients with sleep apnea, 32 had an AHI between 5 and 14 and 11 had an AHI ≥15. The prevalence of SAHS was 10.8% (9 cases). Compared to women without sleep apnea, those with the disease snored more, but there were no differences in other sleep-related symptoms. In the multivariate analysis, age and anthropometric variables, but not EDS, were independently associated with sleep apnea. Conclusion: The prevalence of sleep apnea is higher in middle-aged women diagnosed with breast cancer, although the majority do not present with EDS or other distinguishing characteristics. Age and obesity were predictors for sleep apnea in this population


Subject(s)
Humans , Female , Adolescent , Young Adult , Adult , Middle Aged , Sleep Apnea Syndromes/epidemiology , Breast Neoplasms/diagnosis , Pilot Projects , Breast Neoplasms/pathology , Cross-Sectional Studies , Surveys and Questionnaires , Anthropometry , Disorders of Excessive Somnolence/epidemiology , Risk Factors
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