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Toxicon ; 92: 129-32, 2014 Dec 15.
Article in English | MEDLINE | ID: mdl-25448387

ABSTRACT

Two experiments, each with 10 pregnant ewes (8 treated and 2 controls) were performed to determine if nursing lambs of lactating ewes become intoxicated when the ewes ingest Ipomoea asarifolia but do not show clinical signs themselves. In the first experiment the sheep grazed I. asarifolia in the field while in the second, sheep were maintained in individual bays consuming dry I. asarifolia at 10% and 20% into their ration. In both experiments the lambs remained confined, consuming only their mother's milk. Four of 8 lambs in the grazing experiment and the 4 nursing lambs from the ewes given 20% I. asarifolia showed signs of I. asarifolia poisoning. These results confirm that the tremorgenic compound of I. asarifolia or its toxic metabolites are eliminated in milk and can intoxicate nursing lambs.


Subject(s)
Ipomoea/chemistry , Maternal-Fetal Exchange/physiology , Milk/chemistry , Plant Poisoning/veterinary , Sheep Diseases/chemically induced , Tremor/veterinary , Animals , Brazil , Female , Ipomoea/toxicity , Pregnancy , Sheep , Tremor/chemically induced
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