ABSTRACT
Calcium pantothenate (CAS no. 137-08-6) is the calcium salt of pantothenic acid (vitamin B5). It is used in cosmetics due to its anti-static and hair conditioning properties. A 53-year-old female nurse's aide presented with intermittent facial eruptions (Figure S1). Patch tests were positive to calcium pantothenate, an ingredient of two of her products (a cleansing milk and a facial tonic). To our knowledge, no previous cases of sensitization from calcium pantothenate have been reported except for one case of systemic dermatitis from a nutritional supplement in a dexpanthenol-sensitized patient.
Subject(s)
Cosmetics/adverse effects , Dermatitis, Allergic Contact/etiology , Facial Dermatoses/chemically induced , Pantothenic Acid/adverse effects , Vitamin B Complex/adverse effects , Delayed Diagnosis , Dermatitis, Allergic Contact/diagnosis , Facial Dermatoses/diagnosis , Female , Humans , Middle Aged , Patch TestsSubject(s)
Abdomen, Acute/etiology , Adenocarcinoma of Lung/secondary , Jejunal Neoplasms/secondary , Lung Neoplasms/pathology , Rare Diseases/complications , Adenocarcinoma of Lung/diagnostic imaging , Brain Neoplasms/secondary , Fatal Outcome , Female , Humans , Jejunal Neoplasms/diagnostic imaging , Male , Middle Aged , Tomography, X-Ray ComputedABSTRACT
BACKGROUND: Liver metastases emerge during the course of colorectal cancer (CRC) in 25-50% of patients. A small proportion of patients present intrabiliary growth. The absence of large series means that little is known about intrabiliary metastasis (IBM), its radiological diagnosis, the most suitable surgical techniques, and its prognostic implications. METHODS: A systematic search without limits was performed. The studies selected included patients with a diagnosis of CRC and associated IBM, either synchronous or metachronous. RESULTS: Of 40 studies selected, 30 were case reports and 10 case series. The median time between diagnosis and IBM was 46.7 months (range 0-180). Most CRC metastases are CK7-/CK20+. Surgical treatment performed ranged from endoscopic resection to major hepatic resections combined with pancreatectomies. It seems that patients with IBM have a better survival than patients without this metastasis. CONCLUSION: In a patient with a history of CRC presenting dilatation of the bile duct, IBM should be considered. More studies are needed to determine the most appropriate type of liver resection. It is also necessary to standardize the definition and terminology of this pathology, since the existing definitions may cause confusion and make it difficult to carry out case studies and case series.
Subject(s)
Biliary Tract Neoplasms/secondary , Colorectal Neoplasms/pathology , Biliary Tract Neoplasms/diagnostic imaging , Biliary Tract Neoplasms/surgery , Biomarkers, Tumor/metabolism , Hepatectomy/methods , Humans , Keratins/metabolism , PrognosisABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Amyloidosis/diagnostic imaging , Pancreas/diagnostic imaging , Pancreas/pathology , Magnetic Resonance Imaging , Diagnosis, DifferentialABSTRACT
Toxoplasma gondii es un protozoo intracelular con elevada prevalencia mundial. La primoinfección en inmunocompetentes puede producir linfadenopatía cervical con microgranulomas, sin necrosis ni células gigantes. En inmunodeprimidos y recién nacidos de madres infectadas durante el embarazo puede producir meningoencefalitis necrosante y afectación multivisceral, donde el microorganismo es visualizado fácilmente. Material y método. Se revisaron los hallazgos anatomopatológicos de los casos de toxoplasmosis del Hospital La Paz (1967-2010). Resultados. Se encontraron 78 casos diagnosticados de toxoplasmosis: 32 necropsias (16 toxoplasmosis congénita y 16 adultos con sida) y 46 biopsias (entre ellas 35 linfadenopatías). Conclusiones. Se describen los hallazgos anatomopatológicos de una serie amplia de toxoplasmosis. La linfadenopatía tipo Piringer-Kuchinka y la encefalitis fueron los cuadros más frecuentes(AU)
