ABSTRACT
La cetoacidosis diabética (CAD) es una complicación de la diabetes mellitus originada por un déficit de insulina que conduce a una hiperglicemia y acidosis derivada del aumento de la oxidación de ácidos grasos hacia cuerpos cetónicos. El objetivo fue caracterizar el comportamiento clínico y epidemiológico de la CAD en la UCI 3 del Hospital General Docente Abel Santamaría Cuadrado , 2010-2012. Se realizó un estudio observacional, descriptivo de corte transversal. Se empleó un universo muestral de 19 diabéticos, los datos fueron procesados en Microsoft Excel y presentados en tablas para su mejor comprensión y análisis. Se encontró un predominio de pacientes diabéticos tipo 1, entre 25 y 34 años de edad. El sexo femenino fue el más afectado. Los principales factores desencadenante de la CDA fueron infección y dosis inadecuada de insulina. La sepsis y el shock fueron identificados como complicaciones frecuentes. Se pudo comprobar que no es infrecuente la CDA en nuestro medio, sobre todo en personas adultas jóvenes. Las complicaciones se presenten habitualmente y pueden llegar a a la muerte. Los indicadores de calidad establecidos mejoraron el pronóstico y la evolución de los pacientes en donde fueron aplicados(AU)
Diabetic ketoacidosis (DKA) is a complication of diabetes mellitus caused by shortage of insulin and leading to hyperglycemia and acidosis resulting from increased oxidation of fatty acids to ketone bodies. The objective was To characterize the clinical and epidemiologic features of DKA in the General Teaching Hospital Abel Santamaría, Intensive Care Unit-3, in the period 2010-2012. An observational, cross-sectional descriptive study was conducted. It was used a sample universe of 19 diabetic patients, and data were processed in Microsoft Excel and presented in tables for better understanding and analysis. It was found a prevalence of type 1 diabetic patients between 25 and 34 years old. Females were the most affected. The main triggering factors for DKA were infection and inadequate insulin dosing. Sepsis and shock were identified as frequent complications. It was found that DKA is not uncommon in our environment, especially in young adults; complications arise and can usually lead to death. Established quality indicators improved prognosis and results for patients in which they were applied(AU)
Subject(s)
Humans , Diabetes Mellitus , Ketosis/complicationsABSTRACT
Precise placement of the electrodes for stimulation of the subthalamic nucleus (STN) in Parkinson's disease (PD) is crucial for the therapeutic benefit. As a result of the mistargeting and misplacement of the electrodes during surgery in 2 patients with PD, we have characterized the neuronal firing in the red nucleus (RN) and observed the effects of stimulation of this nucleus. Although the neuronal firing (mean +/- SD) of the RN (34 +/- 4.4 Hz) resembles that described for the STN (33.1 +/- 16.6 Hz), a higher proportion of cells responded to the movement of the contralateral limbs (70-80%). Stimulation in the area of the RN-induced intolerable side effects without motor improvement. We conclude that the STN and RN have some similar neurophysiological features but can be distinguished intraoperatively. This initial description of the physiological characteristics of the RN in humans will draw attention to the possibility of confusing the RN and STN during intraoperative recording.
