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3.
Med Princ Pract ; 26(3): 286-288, 2017.
Article in English | MEDLINE | ID: mdl-28226323

ABSTRACT

OBJECTIVE: To report on 2 patients with alcoholic cirrhosis who were treated with transjugular intrahepatic portosystemic shunt (TIPS) placement. CLINICAL PRESENTATION AND INTERVENTION: The 2 patients had a history of alcoholic cirrhosis, and TIPS surgery was performed on them. In both cases, 4 months after TIPS placement, proteinuria was observed along with histological alterations characteristic of immune complex membranoproliferative glomerulonephritis (MPGN). CONCLUSION: The TIPS in one patient was successful without immediate complications, while the other patient was referred for a combined liver-kidney transplant. In both cases, immune complex MPGN might have developed after TIPS placement probably due to a reduced immune complex clearance.


Subject(s)
Glomerulonephritis, Membranoproliferative/etiology , Immune Complex Diseases/etiology , Liver Cirrhosis, Alcoholic/surgery , Portasystemic Shunt, Transjugular Intrahepatic/adverse effects , Antigen-Antibody Complex/immunology , Female , Glomerulonephritis, Membranoproliferative/immunology , Humans , Immune Complex Diseases/immunology , Male , Middle Aged
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