ABSTRACT
INTRODUCTION AND OBJECTIVE: The application of epidemiology to the field of neurology is relatively recent although it has become so relevant that it is currently recognized as a new specialty: Neuroepidemiology. The objective of our study was to study the morbid-mortality of neurological disorders. PATIENTS AND METHODS: We made a retrospective investigation of all the patients admitted to the Hospital Central de Beira, Mozambique, between 1 January 1996 and 30 June 1999. The source of information used was the clinical histories and data of the Statistics Department. The basis used for classification of the disorders was the International Classification of Diseases, Ninth Revision-1CD 9CM (3 digits). RESULTS: We found that neurological disorders were fifth in the classification of morbidity and third in mortality. Trauma, infections and vascular causes--in that order--were the most important factors in the morbidity of neurological diseases. The highest mortality rate was seen with infections, vascular and neoplastic etiologies. In our study we found disorders which several investigators consider to be almost nonexistent in Africa, such as multiple sclerosis, subacute combined degeneration of the cord and myasthenia gravis amongst others. The morbidity and mortality found for neurological diseases are similar, in general, to those described in Africa. CONCLUSION: The importance of neurological disorders in healthcare means that it is essential to have a specialist available for their management.
Subject(s)
Brain Diseases/epidemiology , Neurodegenerative Diseases/epidemiology , Neuromuscular Diseases/epidemiology , Adult , Brain Diseases/rehabilitation , Catchment Area, Health , Female , Hospitalization , Humans , Male , Middle Aged , Mozambique/epidemiology , Neurodegenerative Diseases/rehabilitation , Neuromuscular Diseases/rehabilitation , Patient Admission/statistics & numerical data , Retrospective StudiesABSTRACT
Introducción y objetivo. La aplicación de la epidemiología en el campo de la neurología es relativamente reciente aunque ha logrado tal relevancia que se reconoce en la actualidad como una especialidad nueva: la Neuroepidemiología. El objetivo de nuestro trabajo es estudiar la morbimortalidad de las enfermedades neurológicas. Pacientes y métodos. Se investigó retrospectivamente a todos los pacientes ingresados en el Hospital Central de Beira, Mozambique, desde el 1 de enero de 1996 hasta el 30 de junio de 1999; se empleó como fuente de información las historias clínicas y los datos del Departamento de Estadísticas, y se tomó como base para clasificar las enfermedades la Clasificación Internacional de Enfermedades, novena Revisión-ICD 9 CM (3 dígitos). Resultados. Se encontró que las enfermedades neurológicas ocuparon el quinto lugar en morbilidad y el tercero por tasa de mortalidad. Por orden de importancia fueron el trauma, las infecciones y las vasculares las más relevantes dentro de las enfermedades neurológicas en relación con la morbilidad. Las de mayores tasas de mortalidad fueron las infecciosas, vasculares y neoplasias. En nuestro estudio encontramos enfermedades que varios autores consideran prácticamente ausentes en África como la esclerosis múltiple, la degeneración combinada subaguda de la médula y la miastenia gravis, entre otras. La morbilidad y la mortalidad encontradas para las enfermedades neurológicas son similares, en general, a las descritas para África. Conclusión. La importancia de las enfermedades neurológicas en el cuadro de salud hace indispensable la presencia de un especialista para su mejor manejo (AU)
Subject(s)
Middle Aged , Adult , Male , Female , Humans , Neurodegenerative Diseases , Mozambique , Neuromuscular Diseases , Patient Admission , Retrospective Studies , Hospitalization , Brain Diseases , Catchment Area, HealthABSTRACT
A hemangiopericytoma in a male breast was studied by fine needle aspiration (FNA) biopsy. The FNA smears contained tissue clumps showing knob-like formations of atypical cells, spindle-shaped cells and fragments of capillaries lined by normal endothelial cells. Immunocytochemical study showed a positive reaction for vimentin, but a negative reaction for desmin and keratin. Staining for Factor VIII was positive only in the capillaries and endothelial cells. The cytodiagnosis was "mesenchymal tumor." Histopathologic study of the mastectomy specimen made the final diagnosis of hemangiopericytoma. While FNA cytology and immunocytochemistry cannot make a definitive diagnosis of this rare vascular tumor, they can be decisive in planning the surgical treatment, as in the present case.
Subject(s)
Breast Neoplasms/pathology , Hemangiopericytoma/pathology , Adult , Biopsy, Needle , Breast Neoplasms/blood supply , Breast Neoplasms/diagnosis , Breast Neoplasms/surgery , Chromatin/ultrastructure , Cytodiagnosis , Factor VII/analysis , Hemangiopericytoma/diagnosis , Hemangiopericytoma/surgery , Humans , Immunoenzyme Techniques , Immunohistochemistry , Male , Mastectomy , Vimentin/analysisABSTRACT
Cutaneous metastases of vesical carcinoma are an uncommon finding and generally appear amid multisystemic dissemination. We present a case of appearance of multiple cutaneous metastases in the immediate postoperative period of a patient subjected to radical cystectomy, in which this affection was the only sign of metastatic seeding. We discuss the etiopathogeny and possible evolution of similar cases.
