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1.
Mem Inst Oswaldo Cruz ; 89 Suppl 2: 13-5, 1994.
Article in English | MEDLINE | ID: mdl-7565122

ABSTRACT

Monoclonal antibodies (mAbs) and human sera from gametocyte carriers were applied in the bio-assay to test for their transmission-blocking capacity. Competition ELISA's have been developed for the detection of natural transmission blocking antibodies. Approximately 55% of the sera blocking in the bio-assay gave positive results in these competition ELISA's.


Subject(s)
Antibodies, Protozoan/immunology , Antigens, Surface/immunology , Enzyme-Linked Immunosorbent Assay/methods , Immune Sera/immunology , Malaria, Falciparum/immunology , Adult , Humans
2.
Mem. Inst. Oswaldo Cruz ; 89(Suppl.2): 13-15, 1994.
Article in English | LILACS | ID: lil-319960

ABSTRACT

Monoclonal antibodies (mAbs) and human sera from gametocyte carriers were applied in the bio-assay to test for their transmission-blocking capacity. Competition ELISA's have been developed for the detection of natural transmission blocking antibodies. Approximately 55 of the sera blocking in the bio-assay gave positive results in these competition ELISA's.


Subject(s)
Humans , Adult , Antibodies, Protozoan/immunology , Antigens, Surface/immunology , Enzyme-Linked Immunosorbent Assay , Immune Sera , Malaria, Falciparum
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