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1.
Nutrients ; 11(5)2019 May 25.
Article in English | MEDLINE | ID: mdl-31130625

ABSTRACT

Low glycemic index (GI) and/or low glycemic load (GL) are associated with decreased risks of type-2 diabetes and cardiovascular disease. It is therefore relevant to consider GI and GL in the early phases of the development of packaged foods and beverages. This paper proposes a model that predicts GI and GL from macronutrient composition, by quantifying both the impact of glycemic carbohydrates and the GI-lowering effects of nutrients such as proteins, fats and fibers. The precision of the model is illustrated using data on 42 breakfast cereals. The predictions of GI (r = 0.90, median residual = 2.0) and GL (r = 0.96, median residual = 0.40 g) compete well with the precision of the underlying in-vivo data (Standard Error SE = 3.5 for GI). This model can guide product development towards lowering GI and GL, before final confirmation by in vivo testing.


Subject(s)
Blood Glucose/metabolism , Diet , Dietary Carbohydrates/blood , Glycemic Index , Glycemic Load , Models, Biological , Nutrients/pharmacology , Adult , Beverages , Breakfast , Cardiovascular Diseases/prevention & control , Diabetes Mellitus, Type 2/prevention & control , Dietary Fats/pharmacology , Dietary Fiber/pharmacology , Dietary Proteins/pharmacology , Edible Grain , Feeding Behavior , Female , Food Handling , Humans , Male , Middle Aged , Nutrients/blood , Reproducibility of Results , Young Adult
2.
Crit Rev Food Sci Nutr ; 59(7): 1058-1070, 2019.
Article in English | MEDLINE | ID: mdl-29190114

ABSTRACT

Dietary guidelines indicate that complex carbohydrates should provide around half of the calories in a balanced diet, while sugars (i.e., simple carbohydrates) should be limited to no more than 5-10% of total energy intake. To achieve this public health goal a collective effort from different entities including governments, food & beverage industries and consumers is required. Some food companies have committed to continually reduce sugars in their products. Different solutions can be used to replace sugars in food products but it is important to ensure that these solutions are more healthful than the sugars they replace. The objectives of this paper are, (1) to identify carbohydrates and carbohydrates sources to promote and those to limit for dietary intake and food product development, based on current knowledge about the impact of carbohydrates on the development of dental caries, obesity and cardio-metabolic disorders (2) to evaluate the impact of food processing on the quality of carbohydrates and (3) to highlight the challenges of developing healthier products due to the limitations and gaps in food regulations, science & technology and consumer education.


Subject(s)
Diet, Cariogenic , Dietary Carbohydrates , Food Handling , Public Health , Cardiovascular Diseases/etiology , Dental Caries/etiology , Diabetes Mellitus, Type 2/etiology , Diet, Cariogenic/adverse effects , Diet, Cariogenic/classification , Dietary Fiber , Energy Intake , Food Industry , Humans , Metabolic Diseases/etiology , Nutrition Policy , Obesity/etiology
3.
Crit Rev Food Sci Nutr ; 57(8): 1562-1568, 2017 May 24.
Article in English | MEDLINE | ID: mdl-25747755

ABSTRACT

Some countries now incorporate recommendations for increased consumption of whole grain (WG) into local dietary guidelines. Cereal and pseudo-cereal grains are good sources of complex carbohydrates, dietary fiber, proteins, phytochemicals, vitamins and minerals. However, research shows that the large majority of consumers are still falling short of WG consumption goals. To address this, we are actively involved in research to help increase the WG content of processed foods without compromising on taste and texture. In order to ensure consumer trust, the advancement of process technologies in incorporating WG to produce tasty food has to go hand in hand with well designed clinical trials that confirm the health benefits resulting from diets rich in WG.


Subject(s)
Food Handling , Whole Grains/chemistry , Consumer Behavior , Consumer Product Safety , Diet, Healthy , Dietary Fiber/administration & dosage , Dietary Fiber/analysis , Dietary Proteins/administration & dosage , Dietary Proteins/analysis , Energy Intake , Health Knowledge, Attitudes, Practice , Humans , Nutrition Policy , Nutritive Value , Phytochemicals/administration & dosage , Phytochemicals/analysis , Taste
4.
Curr Opin Clin Nutr Metab Care ; 19(4): 310-5, 2016 07.
Article in English | MEDLINE | ID: mdl-27168355

ABSTRACT

PURPOSE OF REVIEW: Dietary sugars play a role in noncommunicable diseases and represent a clear target for reduction. In this context, product reformulation can have a positive impact on health. Several technological solutions are available to replace sugar, all with benefits and limitations. The goal of this review is to describe the main sugar replacement alternatives and discuss their impact on health and product physicochemical properties. RECENT FINDINGS: Although high intensity sweeteners and polyols have been used for a long time to replace sucrose and despite no clear evidence of harm, the trend is today to look for alternatives such as sweet enhancers or alternative sugars such as allulose or tagatose, which are both low caloric. To replace the physical properties of sugars, new trends are to substitute widely used maltodextrins by dietary fibres to confer added health benefits. SUMMARY: A wide range of solutions is currently available to replace dietary sugars and compensate for the impact on bulking properties and sweetness profile of food products.


Subject(s)
Food Technology , Non-Nutritive Sweeteners/therapeutic use , Nutritive Sweeteners/therapeutic use , Dietary Fiber/adverse effects , Dietary Fiber/therapeutic use , Food Preferences , Food Technology/trends , Glucose Metabolism Disorders/diet therapy , Glucose Metabolism Disorders/prevention & control , Humans , Non-Nutritive Sweeteners/adverse effects , Nutritive Sweeteners/adverse effects , Overweight/diet therapy , Overweight/prevention & control , Taste
5.
Carbohydr Res ; 339(14): 2371-80, 2004 Oct 04.
Article in English | MEDLINE | ID: mdl-15388352

ABSTRACT

The structure of the extracellular polysaccharide produced by the mesophilic species, Alteromonas infernus, found in deep-sea hydrothermal vents and grown under laboratory conditions, has been investigated using partial depolymerization, methylation analysis, mass spectrometry and NMR spectroscopy. The repeating units of this polysaccharide is a nonasaccharide with the following structure: [carbohydrate: see text].


Subject(s)
Alteromonas/metabolism , Polysaccharides, Bacterial/chemistry , Carbohydrate Sequence , Molecular Sequence Data , Molecular Structure , Polysaccharides, Bacterial/biosynthesis , Polysaccharides, Bacterial/isolation & purification
6.
J Biol Chem ; 279(24): 24923-8, 2004 Jun 11.
Article in English | MEDLINE | ID: mdl-15051719

ABSTRACT

For any given metabolic pathway, isotope redistribution coefficients (a(ij)) that characterize the specific derivation of each hydrogen atom can be defined. By using quantitative deuterium NMR, the redistribution of deuterium at natural abundance in lactic acid produced by the bacterial fermentation of glucose has been determined for each non-labile hydrogen atom of glucose or water and the hydrogen atoms of lactic acid. Distinct differences are observed in the lactic acid isolated from Lactococcus lactis and Leuconostoc mesenteroides that can be interpreted in terms of the different fermentative pathways used. Specifically, the affiliations observed between the H1, H3, and H4 positions of glucose with methyl and hydroxymethylene of lactic acid can give quantitative information on whether the glycolytic or the reductive pentose-phosphate pathway was involved in glucose catabolism.


Subject(s)
Fermentation , Glucose/metabolism , Lactic Acid/metabolism , Lactococcus lactis/metabolism , Leuconostoc/metabolism , Magnetic Resonance Spectroscopy
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