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1.
AJNR Am J Neuroradiol ; 41(8): 1384-1387, 2020 08.
Article in English | MEDLINE | ID: mdl-32554425

ABSTRACT

Coronavirus disease 2019 (COVID-19) is a viral infection caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), which spreads rapidly from person to person and manifests in most symptomatic patients as a respiratory illness, similar to prior SARS viruses. Neurologic manifestations of COVID-19 are uncommon; those so far reported include encephalopathy, stroke from large-vessel occlusion, and polyneuropathy. We report a unique neurologic complication of COVID-19 in a patient who had extensive cerebral small-vessel ischemic lesions resembling cerebral vasculitis in a characteristic combined imaging pattern of ischemia, hemorrhage, and punctuate postcontrast enhancement. Also, a characteristic lower extremity skin rash was present in our patient. Our observation lends support to the increasingly suspected mechanism of "endotheliitis" associated with this novel coronavirus.


Subject(s)
Betacoronavirus , Coronavirus Infections/complications , Pneumonia, Viral/complications , Vasculitis, Central Nervous System/diagnostic imaging , Aged , COVID-19 , Humans , Magnetic Resonance Imaging , Male , Multimodal Imaging , Pandemics , SARS-CoV-2 , Tomography, X-Ray Computed , Vasculitis, Central Nervous System/etiology
2.
Anim Reprod Sci ; 130(3-4): 141-6, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22326609

ABSTRACT

Often, the welfare of sheep and goats is focussed on flock/herd management and the major issues surrounding parturition and early development of lambs/kids. There is an increased interest in the way we manage domestic species and small ruminants are perceived as having a green and welfare friendly image. The management of reproduction in these species has the potential to affect this perception and the limiting factors for these procedures are discussed. Discussion of genetic modification and manipulation has become a focal point in the critical appraisal of the management of farmed livestock and the importance of the consideration of the mental health and well being of the animal is considered as an important part of this analysis. The diversity of options that are available for this analysis and the application of these options is discussed.


Subject(s)
Animal Welfare , Breeding/methods , Goats/physiology , Reproduction/physiology , Sheep/physiology , Animals , Female , Male , Pregnancy
3.
Rev Mal Respir ; 29(1): 70-3, 2012 Jan.
Article in French | MEDLINE | ID: mdl-22240223

ABSTRACT

INTRODUCTION: Scwhannomas are uncommon neurogenic tumors of the mediastinum. Most of them are located in the posterior mediastinum usually in the paralateral gutters. We report the case of an uncommon localisation of such a tumour appended to the right vagus nerve in the middle mediastinum. CASE REPORT: The patient was 50 years old and complained of thoracic pain, shortness of breath and dysphagia. CT scanning of thorax and abdomen revealed a heterogeneous mass in the middle mediastinum, which was not visible on plain radiography. Further investigation included transoesophageal ultrasound and PET scan. The diagnosis was confirmed by histopathology after mini video-assisted thoracotomy. The schwannoma was entirely removed without any post-surgical complications. CONCLUSION: We report a novel case of schwannoma arising from the vagus nerve and review the diagnostic strategies. PET scanning has poor sensitivity and specificity and does not therefore contribute to confirm the diagnosis which depends on exploring the mediastimun surgically.


Subject(s)
Cranial Nerve Neoplasms/diagnosis , Cranial Nerve Neoplasms/therapy , Neurilemmoma/diagnosis , Neurilemmoma/therapy , Vagus Nerve Diseases/diagnosis , Vagus Nerve Diseases/therapy , Vagus Nerve , Cranial Nerve Neoplasms/pathology , Diagnostic Techniques, Surgical , Humans , Incidental Findings , Male , Middle Aged , Neurilemmoma/pathology , Pancreatitis, Chronic/diagnosis , Pancreatitis, Chronic/diagnostic imaging , Pancreatitis, Chronic/surgery , Radiography, Thoracic , Vagus Nerve/pathology , Vagus Nerve Diseases/pathology
4.
Rev Sci Tech ; 25(1): 233-51, 2006 Apr.
Article in English | MEDLINE | ID: mdl-16796052

ABSTRACT

Controlling transboundary diseases requires an inclusive and collaborative international approach. Decisions should be taken (and seen to be taken) on advice from multidisciplinary teams of scientists and representatives from all groups significantly affected by the disease (the 'stakeholders'). Changes in trade and travel mean that, unless a new model is developed for disease prevention, there is a real possibility that transboundary animal diseases will become increasingly difficult to control. The traditional government approach of dealing almost exclusively with the commercial sector of the livestock industry is no longer sufficient, and new ways must be found to include all sectors, including 'grey' husbandry (fragmented, disparate groups whose involvement with animals may range from the legal and responsible to the unsanctioned and/or illegal). The increasing convergence of human and animal health issues makes it imperative to make the best possible use of new tools. The particular challenges confronting veterinary science are: preventing the introduction of disease, rapidly identifying disease and controlling epidemics. This paper focuses on the United Kingdom to investigate the inadequacies of current approaches, identify needs, offer recommendations and propose a new approach to disease control, which emphasises global considerations. The objectives are: better participation across the entire sector, better communication, better science and better decision-making, all of which should lead to better security from disease.


Subject(s)
Animal Diseases/prevention & control , Decision Making , Disease Outbreaks/veterinary , Interdisciplinary Communication , Public Health , Animal Diseases/epidemiology , Animal Identification Systems , Animals , Disaster Planning , Disease Notification , Disease Outbreaks/prevention & control , Geographic Information Systems , Humans , Sentinel Surveillance/veterinary , United Kingdom
5.
Vet Rec ; 154(16): 510; discussion 510-1, 2004 Apr 17.
Article in English | MEDLINE | ID: mdl-15130060
8.
Vet Rec ; 150(22): 700, 2002 Jun 01.
Article in English | MEDLINE | ID: mdl-12074246
9.
Rev Sci Tech ; 21(3): 877-83, 2002 Dec.
Article in English | MEDLINE | ID: mdl-12523722

ABSTRACT

The management of the foot and mouth disease (FMD) epidemic which occurred in the United Kingdom (UK) in 2001 resulted in widespread animal welfare problems. These problems arose firstly because of the large numbers of animals slaughtered to bring the epidemic under control, which meant that the conditions under which animals were slaughtered and the manner in which this was carried out often breached regulations concerning welfare at slaughter. Secondly, the restrictions imposed on movements, especially animal movements, resulted in what appeared to be readily avoidable difficulties with livestock dying from, for example, food shortages and pregnant animals giving birth under unsuitable conditions. This brief review is based on the personal experiences of the authors as well as relevant observations and reports from a variety of sources.


Subject(s)
Animal Welfare , Disease Outbreaks/veterinary , Euthanasia, Animal/methods , Foot-and-Mouth Disease/epidemiology , Foot-and-Mouth Disease/prevention & control , Animals , Communicable Disease Control/methods , Disease Outbreaks/prevention & control , Transportation , United Kingdom/epidemiology
10.
Int J Syst Evol Microbiol ; 50 Pt 2: 525-528, 2000 Mar.
Article in English | MEDLINE | ID: mdl-10758856

ABSTRACT

A rod (0.3-0.4 micron x 3-10 microns) to filamentous (up to 40 microns) non-motile methanogenic bacterium, designated strain FPiT (T = type strain), was isolated from ricefield soil in the Philippines. The strain uses H2 + CO2 or formate for growth and produces CH4. Optimum growth temperature is 40 degrees C; no growth is observed at 15 degrees C or 45 degrees C. Optimum pH for growth is 7; no growth is observed at pH 5.5 or 9.0. Strain FPiT is halotolerant and grows at NaCl concentrations of 0-25 g l-1. The G + C content of its DNA is 31 mol%. Based on 16S rRNA gene sequence analysis, the isolate was identified as a new species of the genus Methanobacterium: Methanobacterium oryzae sp. nov. The type strain is FPiT (= DSM 11106T).


Subject(s)
Methanobacterium/classification , Oryza , Soil Microbiology , Agriculture , Base Composition , DNA, Bacterial/chemistry , DNA, Bacterial/genetics , DNA, Ribosomal/chemistry , DNA, Ribosomal/genetics , Genes, rRNA , Methane/metabolism , Methanobacterium/genetics , Methanobacterium/isolation & purification , Methanobacterium/physiology , Molecular Sequence Data , Philippines , Phylogeny , RNA, Ribosomal, 16S/genetics , Sequence Analysis, DNA , Temperature
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