Prevalencia de resistencia a insulina en una población de jóvenes adultos. Relación con el estado ponderal / Prevalence of insulin resistance in a young adult population. relationship with weight status

Calcular la prevalencia de la resistencia a la insulina mediante índice HOMA (homeostatic model assessment) e insulinemia basal, y estudiar su asociación con estados de sobrepeso según índice de masa corporal (IMC) y perímetro de cintura (PC) en población adulta joven de un centro de salud. Pacientes y métodos Se estudió una serie de 118 jóvenes de 18 y 19 años, no diabéticos, pertenecientes a un centro de salud de atención primaria, con los que se contactó telefónicamente y en los que se determinaron el IMC, PC, HOMA e insulinemia entre otros parámetros. Resultados Un 9,3% de la muestra presentaba cifras de HOMA ≥ al P90 (HOMA≥ 3,15), 50% en el grupo de obesidad. Un 11% presentaron cifras de insulinemia ≥ al P90 (16,9). Según IMC, presentan sobrepeso un 17,8% (26,5% hombres y 11,6% mujeres) y obesidad un 6,8% (6,1% hombres y 7,2% de mujeres). Las cifras de obesidad según PC fueron de 5,71% si se consideraba cintura a nivel de punto medio y 15,38% si se consideraba a nivel de cresta ilíaca. Existía una correlación significativa del HOMA con aumento de peso, IMC, PC, tensión arterial sistólica, triglicéridos y glucemia, mientras que sólo la había entre insulinemia y aumento de PC y disminución de cifras de fracción de colesterol unido a proteínas de alta densidad (HDL).Conclusión En estaserie de jóvenes adultos, el aumento de IMC y de PC se asocia con aumento de la resistencia a insulina. La frecuencia de HOMA elevado en personas obesas fue del 50% (AU)

Aim To estimate the prevalence of insulin resistance using both the Homeostatic Model Assessment (HOMA) index and basal insulinemia, and to analyze its relationship to overweight, as measured by body mass index (BMI) and waist circumference (WC).Patients and methods A series of 118 non-diabetic young adults aged 18 and 19 years attending a primary care health center were studied. They were contacted by telephone, and their BMI, WC, HOMA and basal insulinemia were measured, among other parameters. Results HOMA values ≥ P90 (HOMA ≥3.15) were found in 9.3% of the sample (50% in the obesity group). Insulinemia ≥ P90 (16,9) was found in 11%. Based on BMI, 17.8% were overweight (26.5% of men, 11.6% of women), and 6.8% were obese (6.1% of men, 7.2% of women). Based on WC, 5.71% were obese when waist was measured at the midpoint and 15.38%, when measured at the iliac crest. HOMA was found to be significantly correlated to weight increase, BMI, WC, systolic blood pressure, triglycerides, and blood glucose, while correlation was only found between insulinemia and increased WC and decreased high lipoprotein cholesterol (HDL) levels. Conclusion In this young adult sample, increased BMI and WC were associated to increased insulin resistance. High HOMA values were found in 9.3% of subjects (AU)

Prevalence of insulin resistance in a young adult population. Relationship with weight status.

AIM: To estimate the prevalence of insulin resistance using both the Homeostatic Model Assessment (HOMA) index and basal insulinemia, and to analyze its relationship to overweight, as measured by body mass index (BMI) and waist circumference (WC). PATIENTS AND METHODS: A series of 118 non-diabetic young adults aged 18 and 19 years attending a primary care health center were studied. They were contacted by telephone, and their BMI, WC, HOMA and basal insulinemia were measured, among other parameters. RESULTS: HOMA values ≥ P90 (HOMA ≥3.15) were found in 9.3% of the sample (50% in the obesity group). Insulinemia ≥ P90 (16,9) was found in 11%. Based on BMI, 17.8% were overweight (26.5% of men, 11.6% of women), and 6.8% were obese (6.1% of men, 7.2% of women). Based on WC, 5.71% were obese when waist was measured at the midpoint and 15.38%, when measured at the iliac crest. HOMA was found to be significantly correlated to weight increase, BMI, WC, systolic blood pressure, triglycerides, and blood glucose, while correlation was only found between insulinemia and increased WC and decreased high lipoprotein cholesterol (HDL) levels. CONCLUSION: In this young adult sample, increased BMI and WC were associated to increased insulin resistance. High HOMA values were found in 9.3% of subjects.