Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 17 de 17
Filter
1.
Tob Control ; 10 Suppl 1: i17-23, 2001.
Article in English | MEDLINE | ID: mdl-11740040

ABSTRACT

OBJECTIVE: To assess beliefs about the tar and nicotine delivery characteristics and health benefits of Light and Ultra Light cigarettes among cigarette smokers. DESIGN: Random digit dialed telephone survey conducted in September 1999. SUBJECTS: Daily smokers (n = 2120) of Regular (46%), Light (39%), and Ultra Light (15%) cigarettes in the USA. The sample was weighted to match the US smoker population on age, sex, and ethnicity. MAIN OUTCOME MEASURES: Beliefs about Light and Ultra Light cigarettes were summarised on three dimensions: Safety (reduced health risk), Delivery (lowered tar and nicotine delivery), and Sensation (less harsh). RESULTS: Most smokers believed Lights and Ultra Lights were less harsh and delivered less tar and nicotine. On average, smokers believed that Lights afforded a 25% reduction in risk, and Ultra Lights a 33% reduction in risk. Light and Ultra Light cigarette smokers evaluated the risks of their own cigarette types more favourably. Light smokers had greater interest in quitting than Ultra Light smokers. Quitting intention was modestly related to beliefs about these cigarettes. Believing that Lights and Ultra Lights delivered less tar and nicotine and that they were less harsh each independently contributed to the belief that these cigarettes were safer. CONCLUSIONS: Many Light and Ultra Light smokers believe that smoking these cigarettes impart a substantial health benefit, due in part to their experience that these cigarettes are less harsh and the belief that these cigarettes deliver less tar.


Subject(s)
Health Knowledge, Attitudes, Practice , Nicotine/analysis , Smoke/analysis , Smoking/psychology , Tars/analysis , Adult , Analysis of Variance , Female , Humans , Interviews as Topic , Male , Risk Factors , Set, Psychology , Nicotiana , Tobacco Use Cessation/psychology
2.
Tob Control ; 10 Suppl 1: i24-32, 2001.
Article in English | MEDLINE | ID: mdl-11740041

ABSTRACT

OBJECTIVE: To test the impact of three health messages focusing on vent holes, sensory effects of Light and Ultra Light cigarettes, or health consequences of smoking, respectively, on beliefs and quitting intentions. DESIGN: In the course of a random digit dialed telephone survey, subjects were randomised to hear one of three messages. To test the effects of the messages, beliefs and quitting intentions were assessed both pre- and post-message. PARTICIPANTS: Daily smokers (n = 2120) of Regular (46%), Light (39%), and Ultra Light (15%) cigarettes in the USA. The sample was weighted to match the US smoker population on age, sex, and ethnicity. MAIN OUTCOME MEASURES: Beliefs were summarised on three dimensions: Safety (reduced health risk), Delivery (lower tar and nicotine delivery), and Sensation (less harsh). Quitting interest was captured by the "quit index", an aggregate measure of quitting interest and intent. RESULTS: The message focusing on smokers' sensory perceptions of Light and Ultra Light cigarettes resulted in the most positive change in beliefs about safety, delivery, and intent to quit, and was particularly effective among those who believed that these cigarettes were less harsh. The effect was most pronounced among young adults, and among smokers of Light and Ultra Light brands who most endorsed their sensory benefits. CONCLUSIONS: Addressing smokers' sensory experience that Light and Ultra Light cigarettes feel less harsh may be a promising strategy for changing their misconceptions about these cigarettes and enhancing their interest in quitting. Media counter-advertising on Lights and Ultra Lights, focusing on sensory aspects of these cigarettes, may be an important part of tobacco control efforts.


Subject(s)
Health Education/methods , Nicotiana , Nicotine/analysis , Smoke/analysis , Tars/analysis , Tobacco Use Cessation/psychology , Adult , Attitude to Health , Communication , Humans , Interviews as Topic
3.
Drug Alcohol Depend ; 64(1): 35-46, 2001 Sep 01.
Article in English | MEDLINE | ID: mdl-11470339

ABSTRACT

The study evaluated the efficacy of the Committed Quitters Program (CQP), a computer-tailored set of printed behavioral support materials offered free to purchasers of NicoDerm CQ patches, as a supplement to the nicotine patch and the standard brief User's Guide (UG) and audiotape. Callers to the CQP enrollment were randomized to either CQP (n=1854) or just the UG (n=1829). Abstinence and use of program materials were assessed by telephone interview at 6 and 12 weeks (the latter falling 2 weeks after patch use was to be discontinued). Considering all respondents, abstinence rates did not differ significantly between the UG and CQP groups. As expected, among those who reported they used their assigned materials (80.1% of the sample) smokers who received CQP demonstrated higher quit rates at both 6 weeks (38.8% v. 30.7%) and 12 weeks (18.2% v. 11.1%), compared to the UG group. Among those who used it, the Committed Quitters Program proved to be an effective behavioral treatment, improving quit rates over nicotine replacement therapy and a brief untailored written guide and audiotape.


Subject(s)
Nicotine/therapeutic use , Smoking Cessation/methods , Administration, Cutaneous , Adult , Behavior Therapy , Combined Modality Therapy , Drug Delivery Systems/methods , Female , Follow-Up Studies , Humans , Interviews as Topic , Logistic Models , Male , Middle Aged , Outcome Assessment, Health Care , Patient Compliance , Time Factors , Treatment Outcome
4.
J Nurs Scholarsh ; 33(1): 27-32, 2001.
Article in English | MEDLINE | ID: mdl-11253577

ABSTRACT

PURPOSE: To examine the relationship between self-reported and electronically monitored adherence to a recommended asthma treatment and to assess the accuracy of the diary data reported by school-age children. DESIGN: A randomized, controlled clinical trial of the effectiveness of an asthma self-management program. The relationship between self-reported and electronically recorded daily peak expiratory flow rate (PEFR) adherence was assessed in a sample of 42 children, ages 7 through 11 years with moderate to severe asthma in one community in West Virginia, USA. Cognitive social learning theory served as the framework for the intervention. METHODS: At-home adherence to PEFR monitoring during the 5-week study was evaluated using the self-report Asthma Diary and an electronic PEFR meter. Recommended twice daily (morning and evening) PEFR monitoring was measured. RESULTS: Self-reported and electronically recorded PEFR adherence were modestly correlated. Self-reported adherence was significantly higher than electronically monitored adherence during Week 5. Accuracy of the self-reported PEFR declined over time, and over half of the children fabricated at least one PEFR value during the final week of the study. CONCLUSIONS: Clinicians often evaluate the efficacy of prescribed treatment for children with chronic conditions based on the children's self-reported diary data. The findings indicate that these children's self-reported adherence behaviors contained errors. Parent education regarding supervision of children's adherence, including validating the accuracy of diary data, is critical for successful self-management in children with chronic conditions.


Subject(s)
Asthma/therapy , Medical Records , Patient Compliance , Peak Expiratory Flow Rate , Self Care , Child , Diagnosis, Computer-Assisted , Female , Humans , Male , Patient Education as Topic , Randomized Controlled Trials as Topic/statistics & numerical data , Reproducibility of Results , Statistics, Nonparametric
5.
Adv Ren Replace Ther ; 7(4 Suppl 1): S11-20, 2000 Oct.
Article in English | MEDLINE | ID: mdl-11053582

ABSTRACT

Dialysis dose has been established as a determinant of morbidity and mortality in chronic hemodialysis patients. To identify remediable barriers to the delivery of adequate hemodialysis, we examined factors that affected adherence to prescribed dialysis dose. End-Stage Renal Disease (ESRD) Network 4 facilities that fell into the lowest quintile in measures of dialysis adequacy were studied. At the time of this study, Network 4 was composed of 178 dialysis facilities in Delaware and Pennsylvania. Those 29 facilities had an average delivered urea reduction ratio (URR) of <0.67 and/or 71% of patients with a URR of 0.65. (The mean URR value of Network 4 was 0. 699 with a compliance ratio of 80%.) Dialysis treatment sheets were reviewed for all patients in the 29 facilities for all treatments during a calendar week. Predialysis and postdialysis blood urea nitrogen (BUN) values from 1 treatment during this week were used to calculate URR and Kt/V. A total of 1,339 patients with a mean age of 61.9 +/- 15.1 years and a mean duration of ESRD of 3.4 +/- 3.3 years were dialyzed in the 29 units. Mean prescribed duration of dialysis (T) was 219 +/- 26 min. with a mean blood flow rate (BFR) of 393 +/- 62 mL/min. Concordance between the prescribed and delivered T (-5 min), BFR (-50 mL/min), and hemodialyzer were assessed, by patient, for each treatment (Tx). Characteristics of a delivered Kt/V < 1.2 were duration <4 hours, BFR < 350 mL/min, patient weight > 100 kg, and delivered BFR 50 mL/min less than prescribed BFR. Multivariate analysis of the relationship between delivered dose of dialysis and patients and treatment characteristics identified black race, male gender, and younger age as demographic factors associated with low delivered dose. Potential remediable barriers identified by this analysis included reduced treatment time (>10%) and use of catheters for angioaccess. These data suggest components of the dialysis process that might be targeted in future quality improvement projects to improve the adequacy of dialysis delivery.


Subject(s)
Kidney Failure, Chronic/therapy , Renal Dialysis/methods , Renal Dialysis/standards , Adult , Aged , Catheters, Indwelling , Centers for Medicare and Medicaid Services, U.S. , Delaware , Female , Humans , Kidney Failure, Chronic/blood , Male , Middle Aged , Multivariate Analysis , Pennsylvania , Quality Assurance, Health Care , Time Factors , Total Quality Management , United States , Urea/blood
6.
Adv Ren Replace Ther ; 7(4 Suppl 1): S21-30, 2000 Oct.
Article in English | MEDLINE | ID: mdl-11053583

ABSTRACT

Delivery of an inadequate dose of hemodialysis is associated with a significant increase in the relative risk of both hospitalization and death. We hypothesized that noncompliance with the dialysis prescription, defined as failure to achieve the prescribed blood flow, failure to dialyze for the prescribed duration, or failure to use the prescribed dialyzer, was a significant factor in patients not achieving a urea reduction ratio (URR) of > or =0.65. We identified the 29 dialysis facilities in ESRD Network 4 that had the lowest average URR and/or lowest percent of patients with a URR > or =0.65 based on quarterly data reports. Each facility was surveyed by review of all dialysis treatment sheets from a single week by network staff to evaluate for noncompliance with the dialysis prescription. Facility-specific data were reported back to each facility. Each facility was required to develop a facility-specific quality improvement plan after receiving intensive education on the quality improvement process. After 9 months the facilities were resurveyed. Although the compliance with the dialysis prescription decreased from 54.0% to 53.6% (P =.026), the delivered URR increased from 0.679 +/- 0.072 to 0.688 +/- 0.070 (P =.026) with an increase in the percentage of patients with a URR > or = 0.65 from 69.7% to 75% (P =.0096). Kt/V increased from 1.37 +/- 0.26 to 1.41 +/- 0.27 (P =. 0001). Analysis of the process changes instituted by the individual facilities showed an increase in the prescribed dose of dialysis. Thus, although the process goal of improved compliance with the dialysis prescription was not achieved, the outcome goal of an increased delivered dose of dialysis was met through an alternative process change of an augmented dialysis prescription.


Subject(s)
Kidney Failure, Chronic/therapy , Quality Assurance, Health Care , Renal Dialysis/methods , Renal Dialysis/standards , Aged , Centers for Medicare and Medicaid Services, U.S. , Female , Humans , Male , Middle Aged , Prescriptions , Total Quality Management , United States
7.
Arch Intern Med ; 160(11): 1675-81, 2000 Jun 12.
Article in English | MEDLINE | ID: mdl-10847261

ABSTRACT

BACKGROUND: Standard, generic self-help materials have been largely ineffective as behavioral treatments for smoking cessation. In contrast, self-help programs tailored to the needs of specific smokers have shown promise in facilitating quitting. OBJECTIVE: To evaluate the incremental efficacy of the Committed Quitters Program (CQP), a set of computer-tailored materials offered to purchasers of nicotine polacrilex gum, compared with a briefuntailored user's guide and audiotape, both as supplements to nicotine replacement therapy. METHODS: We conducted a randomized, open-label trial with 3 parallel arms. Subjects were smokers who purchased 2- or 4-mg nicotine polacrilex gum and called the CQP toll-free enrollment line. Three thousand six hundred twenty-seven subjects consented to participate in 1 of 3 study arms: (1) those receiving the CQP materials (CQP group, n= 1,217), (2) those receiving CQP materials and an outbound telephone call (CQP + C group, n= 1,207); and (3) those receiving no supplemental intervention beyond the user's guide and audiotape that were prepackaged with the nicotine polacrilex gum (UG group, n= 1,203). Twenty-eight-day continuous abstinence rates were assessed by telephone interviews at 6 weeks and 10-week continuous rates at 12 weeks into treatment. RESULTS: Abstinence rates among respondents at the 6- and 12-week assessments were significantly higher for the CQP (36.2% and 27.6%) and CQP + C (35.5% and 27.3%) groups compared with the UG group (24.7% and 17.7%) at both intervals. The quit rates for the CQP and CQP + C groups were almost identical. CONCLUSIONS: The CQP proved to be an effective behavioral treatment, enhancing quit rates over and above nicotine replacement therapy and a brief untailored written guide and audiotape.


Subject(s)
Chewing Gum , Nicotine/analogs & derivatives , Polymethacrylic Acids/therapeutic use , Polyvinyls/therapeutic use , Smoking Cessation/methods , Therapy, Computer-Assisted/methods , Adult , Behavior Therapy/methods , Behavior Therapy/statistics & numerical data , Combined Modality Therapy , Follow-Up Studies , Humans , Interviews as Topic/methods , Middle Aged , Nicotine/therapeutic use , Patient Dropouts , Smoking Cessation/statistics & numerical data , Telephone , Therapy, Computer-Assisted/statistics & numerical data , Time Factors , Tobacco Use Cessation Devices
8.
J Sch Nurs ; 15(1): 16-22, 1999 Feb.
Article in English | MEDLINE | ID: mdl-10347445

ABSTRACT

Geographical relocation, with transfer to a new school, is a life transition experienced by many adolescents. The normal developmental tasks of adolescence may complicate the transition for relocated teens, particularly those with inadequate coping skills. This 2-year study, conducted in an upper-middle-income suburban community in the Northeast, with highly mobile students, compared the effects of relocation on 43 teens with matched non-relocated controls. While statistical significance was found in differences between the relocated and non-relocated groups, the relocated teens were only mildly anxious. There were no significant differences between the groups for depression, hostility, life events, or coping. Implications for schools and school nursing regarding health promotion interventions with relocated adolescents are discussed.


Subject(s)
Adaptation, Psychological , Population Dynamics , Psychology, Adolescent , Schools , Stress, Psychological/psychology , Students/psychology , Adolescent , Case-Control Studies , Female , Happiness , Humans , Life Change Events , Male , New England , Nursing Methodology Research , School Nursing , Stress, Psychological/nursing , Stress, Psychological/prevention & control , Surveys and Questionnaires
9.
Ann Behav Med ; 20(1): 36-8, 1998.
Article in English | MEDLINE | ID: mdl-9755350

ABSTRACT

Self-report is a frequently-used method of assessing compliance with prescribed medications in patients with chronic illnesses. Most researchers agree, however, that self-report misrepresents patient adherence to regimen prescription. In this randomized, controlled study evaluating inhaler medication compliance, diary data was compared to electronic monitoring in 55 adults with asthma. Subjects randomized to the treatment group received a six-week self-management program. An electronic monitor, the MDI Chronolog, was used in this study to assess inhaler use. The MDI Chronolog records the date and time of each inhaled activation. The self-report measure used was a daily asthma diary. Subjects were asked to use their inhaled medications as usual and record the date and time they administered their medication over a one-week period. Moderate correlations (rs = .55, Mdnd = 95.8, Mdnc = 91.6) were found when comparing the number of administrations calculated using the MDI Chronolog to the number of administrations reported in the subject's diary. When the dosing interval was examined, however, the correlation was weaker (rs = .44, Mdndiary = 92.8, Mdnchronolog = 37.5). In each case, self-reported compliance was higher than monitored adherence.


Subject(s)
Anti-Asthmatic Agents/administration & dosage , Asthma/drug therapy , Medical Records/statistics & numerical data , Monitoring, Physiologic/instrumentation , Administration, Inhalation , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Reproducibility of Results
10.
Qual Life Res ; 7(1): 57-65, 1998 Jan.
Article in English | MEDLINE | ID: mdl-9481151

ABSTRACT

The purpose of this report is to examine health-related quality of life (HRQoL) as measured by the Medical Outcomes Study Short Form-36, across patient populations with chronic disorders and to compare quality of life (QoL) in these subjects with normative data on healthy persons. Six studies, within the Center for Research in Chronic Disorders at the University of Pittsburgh School of Nursing, in patients with urinary incontinence, prostate cancer, chronic obstructive pulmonary disease (COPD), acquired immune deficiency syndrome (AIDS), fibromyalgia and hyperlipidaemia provided the data for analysis. The results demonstrated that not only did the prostate cancer and hyperlipidaemia patients have the highest QoL across the chronic disorders, but their QoL was comparable to normative data on healthy persons. Homebound, elderly, incontinent patients had the lowest QoL for physical functioning, whereas patients hospitalized with AIDS had the lowest QoL in general health and social functioning. Patients with COPD had the lowest QoL in role-physical, role-emotional and mental health. Patients with fibromyalgia had the lowest QoL in bodily pain and vitality. Compared to normative data, patients with urinary incontinence, COPD, AIDS and fibromyalgia generally had lower QoL. Prostate cancer and hyperlipidaemia patients had QoL comparable to normative data. Compared to normative data, patients with urinary incontinence, COPD, AIDS and fibromyalgia had more variability for role-emotional. AIDS patients had more variability on physical functioning, bodily pain and social functioning compared to the normative data. These data suggest that patients with various chronic disorders may have QoL that is lower in most domains compared to a healthy population. However, there may be differences in the domains affected as well as the extent of variation across specific chronic disorders.


Subject(s)
Chronic Disease/psychology , Health Status , Psychometrics , Quality of Life , Surveys and Questionnaires , Aged , Case-Control Studies , Female , Humans , Male , Middle Aged , Reproducibility of Results
11.
Holist Nurs Pract ; 11(2): 60-8, 1997 Jan.
Article in English | MEDLINE | ID: mdl-9035622

ABSTRACT

The article reports a study examining the level of rejection of the suicide victim by the surviving widow and the suicide survivor's experiences of abuse. The 49 female suicide survivors who participated in this study were part of a larger nursing postvention study. Descriptive statistics and the nonparametric Spearman correlation for a two-tailed test (a < 0.05) were used to analyze the data. Results showed that 65.3% of the survivors of suicide had experienced some form of abuse, the most frequent being verbal abuse. Experiences of abuse may affect the bereavement process and coping strategies in surviving the suicide of a spouse.


Subject(s)
Child Abuse/psychology , Nursing Assessment , Suicide, Attempted/psychology , Survivors/psychology , Widowhood/psychology , Adaptation, Psychological , Adult , Child , Female , Humans , Middle Aged , Rejection, Psychology , Statistics, Nonparametric , Surveys and Questionnaires
12.
Comput Nurs ; 14(6): 323-9; quiz 330-2, 1996.
Article in English | MEDLINE | ID: mdl-8972986

ABSTRACT

This article presents an overview of distance mental health screening using Teleform. This technology provides nurses with the ability to have questionnaires administered in one location then processed and scored rapidly at a location some distance away by using a facsimile system and Teleform. The authors examine the process of using Teleform, cite its advantages and disadvantages, discuss its application with rural youth, and suggest implications for school personnel and health-care providers. Technology has facilitated many changes in health-care delivery and increasingly will be instrumental in creating changes. Computer technology can help nursing deliver services swiftly to larger populations.


Subject(s)
Adolescent Health Services/organization & administration , Mass Screening/methods , Mental Health Services/organization & administration , Rural Health Services/organization & administration , School Nursing/organization & administration , Software Validation , Telefacsimile/organization & administration , Adolescent , Humans , Nursing Evaluation Research , Psychiatric Status Rating Scales
14.
Am J Epidemiol ; 139(6): 599-608, 1994 Mar 15.
Article in English | MEDLINE | ID: mdl-8172171

ABSTRACT

This report presents descriptive data on blood lead levels in 530 white women aged 65-87 years and examines the association of blood lead level in this population with specific variables, including age, diet, reproductive and lifestyle factors, and place of residence. Women were recruited from an urban (Baltimore, n = 205) and a rural site (the Monongahela Valley, Pennsylvania, n = 325) during the period 1990-1991. Information on lifestyle, medical history, and demographics was obtained by questionnaire and interview. Blood lead concentrations were measured by atomic absorption spectrophotometry. The mean blood lead level of this cohort (5.3 micrograms/dl) was nearly 60% lower than that reported by a national survey in 1976-1980 for white women aged 65-74 years (12.8 micrograms/dl). Urban women had significantly higher blood lead levels than rural women (p < 0.0001). Urban residence, smoking, alcohol consumption, and years since menopause were positively associated with blood lead level, while body mass index, breast feeding, current estrogen replacement therapy, moderate physical activity, and calcium intake were inversely associated. These data suggest that mean blood lead levels have declined dramatically since 1980. Because it is not known at what level of lead exposure adverse health effects occur, other factors that modify lead levels, metabolism, or susceptibility, such as nutrition and consumption of tobacco and alcohol, become important.


Subject(s)
Lead Poisoning/blood , Lead Poisoning/epidemiology , Life Style , Population Surveillance , Age Factors , Aged , Aged, 80 and over , Baltimore/epidemiology , Body Mass Index , Calcium, Dietary , Cross-Sectional Studies , Exercise , Female , Humans , Lead Poisoning/etiology , Menopause , Multivariate Analysis , Nutrition Surveys , Pennsylvania/epidemiology , Residence Characteristics , Rural Population , Socioeconomic Factors , Urban Population , White People
15.
Health Psychol ; 12(5): 410-5, 1993 Sep.
Article in English | MEDLINE | ID: mdl-8223366

ABSTRACT

Diet, alcohol intake, and leisure-time physical activity were compared cross-sectionally in middle-aged female smokers, ex-smokers, and never smokers and were reassessed approximately 3 years later. At initial contact, there were no group differences in total caloric intake and very few differences in nutrient intake, but alcohol intake of current smokers and ex-smokers was at least 50% greater than that of never smokers, and current smokers reported less physical activity than did ex-smokers and never smokers. Prospective findings were similar: Compared with continuing smokers, ex-smokers did not change their dietary and alcohol intake but significantly increased physical activity. Thus, some adverse behaviors associated with smoking (e.g., alcohol intake) may be due to self-selection to history of smoking, whereas other behaviors (e.g., reduced physical activity) may be more directly related to smoking itself.


Subject(s)
Alcohol Drinking , Diet , Leisure Activities , Smoking , Women , Age Factors , Attitude to Health , Body Mass Index , Cross-Sectional Studies , Energy Intake , Female , Humans , Middle Aged
16.
Ann Epidemiol ; 3(4): 351-7, 1993 Jul.
Article in English | MEDLINE | ID: mdl-8275210

ABSTRACT

The association of physical activity to plasma lipid and lipoprotein levels was examined cross-sectionally in 634 elderly, postmenopausal women whose mean age was 70.7 years. Leisure-time physical activity in kilocalories per week was assessed by the Paffenbarger Questionnaire, a composite index of sports/recreation, stair climbing, and walking. Subjects were categorized by tertile of kilocalories per week from total physical activity, number of flights of stairs climbed, and number of blocks walked. After adjustment for age, body mass index, education, and oral estrogen use, no significant differences were noted in total cholesterol, high-density-lipoprotein cholesterol (HDL-C), HDL2-C, HDL3-C, low-density-lipoprotein cholesterol (LDL-C), or triglycerides across tertile of total activity or number blocks walked. Total cholesterol was significantly different across tertile of number of flights of stairs climbed (P < 0.05), and only a borderline association was noted with LDL-C (P < 0.08). The study suggests that leisure-time physical activity, as measured by the Paffenbarger Questionnaire, is not associated with a favorable lipid profile in elderly, postmenopausal women. Failure to find an association may reflect the relatively small number of women who engaged in moderate- or high-intensity activity.


Subject(s)
Exercise , Lipids/blood , Lipoproteins/blood , Aged , Body Constitution , Female , Humans , Prospective Studies
17.
J Rheumatol ; 20(7): 1170-5, 1993 Jul.
Article in English | MEDLINE | ID: mdl-8371212

ABSTRACT

OBJECTIVE: To examine the relationship of endogenous sex hormones to the severity of radiographic hand osteoarthritis (ROA) in 229 white women, mean age 74 years. METHODS: Hand ROA was graded according to the Kellgren-Lawrence scale and according to individual features of OA: osteophytes, joint space narrowing, subchondral sclerosis, lateral deformity and joint collapse. Two measures of hand ROA were considered: the worst joint score assigned to any one of 10 hand joints and the sum of the scores for the 10 joints. RESULTS: Comparison of the age and obesity adjusted sex hormone concentrations by the worst Kellgren-Lawrence score or the worst score of the individual features of OA revealed little difference. There were no trends in the sex hormone concentrations with increasing severity of hand ROA. CONCLUSIONS: Our results do not support an association between endogenous hormone levels and severity of hand ROA.


Subject(s)
Androgens/blood , Estrogens/blood , Osteoarthritis/blood , Severity of Illness Index , Aged , Aged, 80 and over , Aging/blood , Aging/physiology , Cohort Studies , Female , Hand/diagnostic imaging , Humans , Menopause/physiology , Obesity/complications , Obesity/physiopathology , Osteoarthritis/complications , Osteoarthritis/epidemiology , Prospective Studies , Radiography , Radioimmunoassay , Risk Factors
SELECTION OF CITATIONS
SEARCH DETAIL
...