ABSTRACT
Malignant Melanoma (MM) incidence rate is increasing faster than many other cancer at present time. Its epidemiological and clinical behavior varies within countries. We have studied 113 cases of cutaneous melanoma from 1982-1993, that represents until now the largest series of MM studied in Chile. Superficial Spreading Melanoma was the most common type of MM with 37.5% of total cases followed by Nodular Melanoma 31.2%. Acral Melanoma 22.1%, and Lentigo Malignant Melanoma with 7.8%. MM favored females with 60.2% (n = 68) and males constituted 39.8% (n = 45) of all cases. Median age at diagnosis was 54 years. Primary more frequent location for man was thorax (36.4%) and lower extremities for women (28.6%). Hemorrhage, ulceration and rapid growth of a previously pigmented lesion as the primary cause for first medical visit were associated with high level of invasion, generally over 2 mm. thick. Color change and pruritus were associated with lower level of invasion. Patients in stage I (78.3%) had 1.35 mm of median invasive thickness in the primary lesion and patients in stage II (15.7%) had 3.03 mm.
Subject(s)
Melanoma/epidemiology , Adult , Female , Follow-Up Studies , Humans , Male , Melanoma/pathology , Middle Aged , Neoplasm Invasiveness , Neoplasm StagingABSTRACT
A 45 year old male who manipulated tropical fish ponds developed painless nodular plaques in both hands. Biopsy showed mononuclear infiltrate of the dermis with few granulomata. Repeated cultures revealed M. marinum (diagnosis confirmed at the WHO/PAHO Reference Center in Canada). Good initial results were obtained with single agent therapy with ciprofloxacin. The patient suspended therapy after 11 month and a relapse was observed. Definite cure was obtained with oral cotrimoxazole and topic kanamycin.
Subject(s)
Mycobacterium Infections/diagnosis , Skin Diseases, Infectious/diagnosis , Anti-Bacterial Agents , Drug Therapy, Combination/therapeutic use , Humans , Male , Middle Aged , Mycobacterium Infections/drug therapy , Skin Diseases, Infectious/drug therapyABSTRACT
We report 3 patients operated on for gastric cancer who developed skin metastasis proven by biopsy. Within a year of this complication 2 patients had died, confirming the bad prognosis associated to this finding. No estimates of the frequency of this complication are available in Chile.
Subject(s)
Skin Neoplasms/secondary , Stomach Neoplasms , Adult , Aged , Humans , Male , Prognosis , Skin Neoplasms/mortality , Skin Neoplasms/pathology , Stomach Neoplasms/mortalityABSTRACT
1. Se presentan dos casos de miosis estromal endolinfatica, de distinta evolucion.2. Por constituir una entidad patologica poco frecuente se deben conocer sus caracteristicas clinicas y evolutivas, con el objeto de proponer el tratamiento adecuado. 3. Se comentan los aspectos histologicos. 4. Se hace enfasis en la necesidad de un tratamiento con extirpacion completa de la lesion, para evitar la recidiva, que ensombrece el pronostico
