ABSTRACT
Tularemia is a bacterial zoonosis which is commonly transmitted through tick or insect bites or contact with meat of infected animals. We report the case of a 36-year-old man who developed fever, chills, headaches, and a painful, unilateral, inguinal lymphadenopathy with a red-livid skin discoloration after an insect bite on his abdomen. Ulceroglandular tularemia was diagnosed through polymerase chain reaction (PCR) and serology. Treatment with doxycycline for 21 days resulted in an excellent outcome.
Subject(s)
Insect Bites and Stings , Lymphadenopathy , Tularemia , Adult , Animals , Anti-Bacterial Agents/therapeutic use , Doxycycline/therapeutic use , Francisella tularensis , Humans , Insect Bites and Stings/complications , Lymphadenopathy/etiology , Male , Treatment Outcome , Tularemia/diagnosis , Tularemia/drug therapySubject(s)
Bone Diseases/drug therapy , Histiocytosis, Langerhans-Cell/drug therapy , Skin Diseases/drug therapy , Adrenal Cortex Hormones/therapeutic use , Adult , Aged, 80 and over , Azetidines/therapeutic use , Dermatologic Agents/therapeutic use , Female , Humans , Male , Middle Aged , Off-Label Use , Piperidines/therapeutic use , Thalidomide/therapeutic useABSTRACT
BACKGROUND: Since dermal fillers were introduced in 1981, millions of patients have undergone wrinkle treatment with dermal fillers. Except for autologous fat, all fillers can act as potential foreign bodies, which have the potential ability to induce an immune reaction. Persisting material may induce activation of the immune system and finally granuloma formation. Frequency, histology, and clinical presentation of such foreign body reactions may vary depending on the filler used. CASE REPORT: This case describes a patient who received innumerable filler injections over the last two decades presenting with massive facial granulomas.