[Nephron sparing renal surgery as salvage treatment after failure of radiofrequency thermal ablation in a patient with a single kidney and renal adenocarcinoma]. / Cirugía renal conservadora de nefronas como tratamiento de rescate tras fracaso de la termoablación mediante radiofrecuencia en paciente monorreno con adenocarcinoma renal.

OBJECTIVES: To describe the technique of renal radiofrequency (RF) thermal ablation. Case report of a successful nephron-sparing surgery after failure of the RF thermal ablation of a renal adenocarcinoma in a patient with a single kidney. METHODS: A patient presenting with a renal adenocarcinoma in a single left kidney was treated by RF thermal ablation. The failure of the technique was patent on follow-up after demonstration of a central area of necrosis surrounded by a peripheral contrast enhancing area. Nephron sparing surgery was indicated as salvage procedure. RESULTS: Surgical excision of the tumor with a safety margin, without renal pedicle clamping was undertaken. Fat tissue and hemostatic synthetic material were placed in the surgical bed. Pathology report: renal adenocarcinoma with changes secondary to central necrosis. Twenty-four month postoperative follow-up: fatty renal nodule with small fibrous tracts inside in the area of the tumor. No evidence of contrast enhancing areas. Normal renal function (sCr 0.7 mg/dl, urea 24 mg/dl). CONCLUSIONS: Radiofrequency thermal ablation is a relatively new technique. Its oncological efficacy greatly depends on appropriate case selection. One of its main caveats is achieving an area of tissue ablation enough to completely destroy the tumor. When the technique fails, renal surgery (nephron sparing or not) seems to be the most recommended alternative.

Cirugía renal conservadora de nefronas como tratamiento de rescate tras fracaso de la termoablación mediante radiofrecuencia en paciente monorreno con adenocarcinoma renal / Nephron sparing renal surgery as salvage treatment after failure of radiofrequency thermal ablation in a patient with a single kidney and renal adenocarcinoma

OBJETIVO: Descripción de la técnica de la termoablación renal mediante radiofrecuencia (TARF). Presentación de una cirugía renal conservadora de nefronas como tratamiento exitoso de rescate tras fracaso de la TARF de un adenocarcinoma renal en un paciente monorreno quirúrgico. MÉTODOS: Un adenocarcinoma renal izquierdo parcialmente exofítico en un paciente monoreno es tratado mediante TARF. En el seguimiento de la misma se observa fracaso de dicha técnica al comprobar la existencia de una zona central necrótica rodeada de una zona periférica captadora de contraste. Se decide cirugía renal conservadora como técnica de rescate. RESULTADOS: Extirpación quirúrgica del tumor y tejido renal próximo con margen de seguridad, sin clampaje del pediculo renal. Aposición de tejido graso y material hemostático sintético en el lecho quirúrgico Estudio anatomopatológico: adenocarcinoma renal con cambios secundarios a necrosis en su zona central. Seguimiento postcirugía de 18 meses: nódulo graso renal con pequeños tractos fibrosos en su interior en la zona previamente ocupada por el tumor. Sin evidencia de ninguna zona captante de contraste en el TAC. Función renal normal (Crp 0,7 mg/dl, Urea 24 mg/dl). CONCLUSIONES: La TARF es una técnica relativamente nueva. Su eficacia oncológica depende en gran medida de la selección adecuada de los casos a tratar. Uno de sus principales problemas radica en el hecho de conseguir una zona de ablación tisular suficiente como para destruir totalmente el tumor. En caso de fracaso de la técnica, la cirugía renal (conservadora de nefronas o no) parece la alternativa mas recomendada

OBJECTIVES: To describe the technique of renal radiofrequency (RF) thermal ablation. Case report of a successful nephron-sparing surgery after failure of the RF thermal ablation of a renal adenocarcinoma in a patient with a single kidney. METHODS: A patient presenting with a renal adenocarcinoma in a single left kidney was treated by RF thermal ablation. The failure of the technique was patent on follow-up after demonstration of a central area of necrosis surrounded by a peripheral contrast enhancing area. Nephron sparing surgery was indicated as salvage procedure. RESULTS: Surgical excision of the tumor with a safety margin, without renal pedicle clamping was undertaken. Fat tissue and hemostatic synthetic material were placed in the surgical bed. Pathology report: renal adenocarcinoma with changes secondary to central necrosis. Twenty-four month postoperative follow-up: fatty renal nodule with small fibrous tracts inside in the area of the tumor. No evidence of contrast enhancing areas. Normal renal function (sCr 0.7 mg/dl, urea 24 mg/dl). CONCLUSIONS: Radiofrequency thermal ablation is a relatively new technique. Its oncological efficacy greatly depends on appropriate case selection. One of its main caveats is achieving an area of tissue ablation enough to completely destroy the tumor. When the technique fails, renal surgery (nephron sparing or not) seems to be the most recommended alternative