ABSTRACT
BACKGROUND: An Amerindian genetic background could play an important role in susceptibility to metabolic diseases, which have alarmingly increased in recent decades. Mexico has one of the highest prevalences of metabolic disease worldwide. The purpose of this study was to determine the prevalence of metabolic syndrome and its components in a population with high Amerindian ancestry. METHODS: We performed a descriptive, quantitative, and analytical cross-sectional study of 2596 adult indigenous volunteers from 60 different ethnic groups. Metabolic syndrome and its components were evaluated using the American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement criteria. RESULTS: The overall prevalence of metabolic syndrome in the indigenous Mexican population was 50.3%. Although females had a higher prevalence than males (55.6% vs. 38.2%), the males presented with combinations of metabolic syndrome components that confer a higher risk of cardiovascular disease. The most frequent metabolic syndrome component in both genders was low HDL-cholesterol levels (75.8%). Central obesity was the second most frequent component in females (61%), though it had a low prevalence in males (16.5%). The overall prevalence of elevated blood pressure was 42.7% and was higher in males than females (48.8 vs. 40%). We found no gender differences in the overall prevalence of elevated triglycerides (56.7%) or fasting glucose (27.9%). CONCLUSIONS: We documented that individuals with Amerindian ancestry have a high prevalence of metabolic syndrome. Health policies are needed to control the development of metabolic disorders in a population with high genetic risk.
Subject(s)
Indians, North American/statistics & numerical data , Metabolic Syndrome/epidemiology , Adult , Cross-Sectional Studies , Female , Humans , Male , Metabolic Syndrome/ethnology , Mexico/epidemiology , Middle Aged , Obesity, Abdominal/epidemiology , Obesity, Abdominal/ethnology , Prevalence , Risk FactorsABSTRACT
Objetivo. Determinar los factores asociados a la mortalidad por influenzapA(H1N1) en los pacientes hospitalizados por infección respiratoria agudagrave (IRAG) confirmada por reacción en cadena de la polimerasa (PCR)en el Instituto Mexicano del Seguro Social (IMSS).Material y métodos. En el IMSS en la delegación de Nuevo León entre el1 de junio de 2009 y 9 de marzo de 2010 se realizó un estudio observacionalretrospectivo de casos y controles, utilizando la base de datos del Sistemade Información en Línea para la Vigilancia Epidemiológica de Influenza(SINOLAVE). Se incluyeron 278 pacientes hospitalizados con IRAG (controles)y 50 pacientes con IRAG que fallecieron (casos) debido a la infecciónpor virus influenza pA(H1N1).Resultados. Los factores asociados a la mortalidad en los pacientes hospitalizadospor IRAG debida a influenza pA(H1N1) fueron la edad (OR: 1,03IC95% 1,01-1,05) y la obesidad (OR: 4,44 IC95% 1,85-1,6), utilizando unmodelo de regresión logística.Conclusión. Podemos concluir que en la delegación de Nuevo León delIMSS, la influenza pA(H1N1) afectó principalmente a adultos jóvenes, sinembargo las muertes se presentaron en mayor número en los pacientes alincrementar la edad y en pacientes con alguna comorbilidad.Palabras clave: Influenza pandémica A(H1N1), mortalidad, infección respiratoriaaguda grave, factores de riesgo, razón de probabilidad.
Objective. To determine factors associated with mortality from pAinfluenzA(H1N1) confirmed by polymerase chain reaction (PCR) Inhospitalized patients with severe acute respiratory infection (SARI) in theMexican Social Security Institute (IMSS). Methods. In the IMSS in the Delegation of Nuevo Leon between June 1, 2009 and March9, 2010 a retrospective observational case-control study was conducted using the database ofOnline Information System for Epidemiological Surveillance of Influenza (SINOLAVE). 278inpatients with SARI (controls) and 50 SARI patients who died (cases) due to infection withinfluenza virus pA(H1N1) were included.Results. In the logistic regression model factors associated with mortality in patientshospitalized due to SARI pA influenzA(H1N1) were age (OR: 1.03 95% CI 1.01-1.05) andobesity (OR: 4.44 95 1.85 to 1%, 0.6).Conclusion. We can conclude that the delegation of Nuevo León of the IMSS, pAinfluenzA(H1N1) affects mainly young adults, though the deaths occurred in greater numbersin patients with increasing age and in patients with comorbidities.
Subject(s)
Humans , Male , Female , Middle Aged , Influenza, Human/mortality , Influenza A Virus, H1N1 Subtype , Hospitalization , Respiratory Tract Infections/mortality , Logistic Models , Mexico/epidemiology , Observational Study , Odds Ratio , Pandemics , Retrospective Studies , Risk FactorsABSTRACT
BACKGROUND: A unique, active, timely, low-cost surveillance system for the metropolitan area of Mexico City was established in the mid-1990s. METHODS: The system obtained upper and lower respiratory tract symptoms and eye symptoms from daily interviews for a systematic sample of the general nonhospitalized population living within a 2-km radius of air pollution monitors during 1996-1997. RESULTS: Ozone increments (10 ppb) were associated with upper respiratory symptoms (odds ratio [OR] = 1.003; 95% confidence interval [CI] = 1.002-1.004) and ocular symptoms indicators (OR = 1.005; CI = 1.004-1.007), and with a higher risk of lower respiratory symptoms indicator among nonsmokers (OR = 1.003; CI = 1.002-1.005). Increases in relative humidity reduced the risk of increments of sulfur dioxide on the 3 acute health indicators. Association of PM10 with health indicators varied among the 5 regions. During emergency episodes, symptoms increased sharply when ozone reached 281 ppb, a finding that resulted in a change in the ozone criteria for emergency declaration from 294 to 281 ppb. CONCLUSIONS: This system has been low cost, timely, and useful for local decision making.