ABSTRACT
Sheep infected with Fasciola hepatica for 10 wk acquired a substantial level of resistance to challenge with Schistosoma bovis. The worm burden was reduced by 87.2% (P < 0.01) compared with that of a control group. But when sheep primarily were infected with S. bovis and 6 wk later with F. hepatica, no significant reduction in the S. bovis burden was observed.
Subject(s)
Fascioliasis/veterinary , Schistosomiasis/veterinary , Sheep Diseases/immunology , Analysis of Variance , Animals , Fascioliasis/immunology , Schistosomiasis/immunology , SheepABSTRACT
Crude saline extracts of Trichinella spiralis and T. pseudospiralis infective larvae were studied by Western blot analysis using a monoclonal antibody, named ES/TA2 and produced against T. spiralis larvae. This monoclonal antibody recognized seven major antigenic components in T. spiralis larvae with apparent Mr: 45, 48, 50, 68, 70, 92 and 105 kDa and five in T. pseudospiralis larvae: 38, 50, 70, 72 and 92 kDa. SDS-PAGE of both extracts did not reveal appreciable differences in the range of molecular weights recognized by ES/TA2. These facts show the existence of immunological differences among proteins with apparently identical molecular weights.
